LOCUS       sequence-11244-e        2928 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2928)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2928)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-EPHA1
FEATURES             Location/Qualifiers
     source          1..2928
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggagcggc gctggcccct ggggctaggg ctggtgctgc tgctctgcgc cccgctgccc
       61 ccgggggcgc gcgccaagga agttactctg atggacacaa gcaaggcaca gggagagctg
      121 ggctggctgc tggatccccc aaaagatggg tggagtgaac agcaacagat actgaatggg
      181 acacccctgt acatgtacca ggactgccca atgcaaggac gcagagacac tgaccactgg
      241 cttcgctcca attggatcta ccgcggggag gaggcttccc gcgtccacgt ggagctgcag
      301 ttcaccgtgc gggactgcaa gagtttccct gggggagccg ggcctctggg ctgcaaggag
      361 accttcaacc ttctgtacat ggagagtgac caggatgtgg gcattcagct ccgacggccc
      421 ttgttccaga aggtaaccac ggtggctgca gaccagagct tcaccattcg agaccttgtg
      481 tctggctccg tgaagctgaa tgtggagcgc tgctctctgg gccgcctgac ccgccgtggc
      541 ctctacctcg ctttccacaa cccgggtgcc tgtgtggccc tggtgtctgt ccgggtcttc
      601 taccagcgct gtcctgagac cctgaatggc ttggcccaat tcccagacac tctgcctggc
      661 cccgctgggt tggtggaagt ggcggggacc tgcttgcccc acgcgcgggc cagccccagg
      721 ccctcaggtg caccccgcat gcactgcagc cctgatggcg agtggctggt gcctgtagga
      781 cggtgccact gtgagcctgg ctatgaggaa ggtggcagtg gcgaagcatg tgttgcctgc
      841 cctagcggct cctaccggat ggacatggac acaccccatt gtctcacgtg cccccagcag
      901 agcactgctg agtctgaggg ggccaccatc tgtacctgtg agagcggcca ttacagagct
      961 cccggggagg gcccccaggt ggcatgcaca ggtcccccct cggccccccg aaacctgagc
     1021 ttctctgcct cagggactca gctctccctg cgttgggaac ccccagcaga tacgggggga
     1081 cgccaggatg tcagatacag tgtgaggtgt tcccagtgtc agggcacagc acaggacggg
     1141 gggccctgcc agccctgtgg ggtgggcgtg cacttctcgc cgggggcccg ggggctcacc
     1201 acacctgcag tgcatgtcaa tggccttgaa ccttatgcca actacacctt taatgtggaa
     1261 gcccaaaatg gagtgtcagg gctgggcagc tctggccatg ccagcacctc agtcagcatc
     1321 agcatggggc atgcagagtc actgtcaggc ctgtctctga gactggtgaa gaaagaaccg
     1381 aggcaactag agctgacctg ggcggggtcc cggccccgaa gccctggggc gaacctgacc
     1441 tatgagctgc acgtgctgaa ccaggatgaa gaacggtacc agatggttct agaacccagg
     1501 gtcttgctga cagagctgca gcctgacacc acatacatcg tcagagtccg aatgctgacc
     1561 ccactgggtc ctggcccttt ctcccctgat catgagtttc ggaccagccc accagtgtcc
     1621 aggggcctga ctggaggaga gattgtagcc gtcatctttg ggctgctgct tggtgcagcc
     1681 ttgctgcttg ggattctcgt tttccggtcc aggagagccc agcggcagag gcagcagagg
     1741 cagcgtgacc gcgccaccga tgtggatcga gaggacaagc tgtggctgaa gccttatgtg
     1801 gacctccagg catacgagga ccctgcacag ggagccctgg actttacccg ggagcttgat
     1861 ccagcgtggc tgatggtgga cactgtcata ggagaaggag agtttgggga agtgtatcga
     1921 gggaccctga ggctccccag ccaggactgc aagactgtgg ccattaagac cttaaaagac
     1981 acatccccag gtggccagtg gtggaacttc cttcgagagg caactatcat gggccagttt
     2041 agccacccgc atattctgca tctggaaggc gtcgtcacaa agcgaaagcc gatcatgatc
     2101 atcacagaat ttatggagaa tggagccctg gatgccttcc tgagggagcg ggaggaccag
     2161 ctggtccctg ggcagctagt ggccatgctg cagggcatag catctggcat gaactacctc
     2221 agtaatcaca attatgtcca ccgggacctg gctgccagaa acatcttggt gaatcaaaac
     2281 ctgtgctgca aggtgtctga ctttggcctg actcgcctcc tggatgactt tgatggcaca
     2341 tacgaaaccc agggaggaaa gatccctatc cgttggacag cccctgaagc cattgcccat
     2401 cggatcttca ccacagccag cgatgtgtgg agctttggga ttgtgatgtg ggaggtgctg
     2461 agctttgggg acaagcctta tggggagatg agcaatcagg aggttatgaa gagcattgag
     2521 gatgggtacc ggttgccccc tcctgtggac tgccctgccc ctctgtatga gctcatgaag
     2581 aactgctggg catatgaccg tgcccgccgg ccacacttcc agaagcttca ggcacatctg
     2641 gagcaactgc ttgccaaccc ccactccctg cggaccattg ccaactttga ccccaggatg
     2701 actcttcgcc tgcccagcct gagtggctca gatgggatcc catatcgaac cgtctctgag
     2761 tggctcgagt ccatacgcat gaaacgctac atcctgcact tccactcggc tgggctggac
     2821 accatggagt gtgtgctgga gctgaccgct gaggacctga cgcagatggg aatcacactg
     2881 cccgggcacc agaagcgcat tctttgcagt attcagggat tcaaggac
//
