LOCUS       sequence-11245-e        2952 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2952)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-EPHB1
FEATURES             Location/Qualifiers
     source          1..2952
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggccctgg attatctact actgctcctc ctggcatccg cagtggctgc gatggaagaa
       61 acgttaatgg acaccagaac ggctactgca gagctgggct ggacggccaa tcctgcgtcc
      121 gggtgggaag aagtcagtgg ctacgatgaa aacctgaaca ccatccgcac ctaccaggtg
      181 tgcaatgtct tcgagcccaa ccagaacaat tggctgctca ccaccttcat caaccggcgg
      241 ggggcccatc gcatctacac agagatgcgc ttcactgtga gagactgcag cagcctccct
      301 aatgtcccag gatcctgcaa ggagaccttc aacttgtatt actatgagac tgactctgtc
      361 attgccacca agaagtcagc cttctggtct gaggccccct acctcaaagt agacaccatt
      421 gctgcagatg agagcttctc ccaggtggac tttgggggaa ggctgatgaa ggtaaacaca
      481 gaagtcagga gctttgggcc tcttactcgg aatggttttt acctcgcttt tcaggattat
      541 ggagcctgta tgtctcttct ttctgtccgt gtcttcttca aaaagtgtcc cagcattgtg
      601 caaaattttg cagtgtttcc agagactatg acaggggcag agagcacatc tctggtgatt
      661 gctcggggca catgcatccc caacgcagag gaagtggacg tgcccatcaa actctactgc
      721 aacggggatg gggaatggat ggtgcctatt gggcgatgca cctgcaagcc tggctatgag
      781 cctgagaaca gcgtggcatg caaggcttgc cctgcaggga cattcaaggc cagccaggaa
      841 gctgaaggct gctcccactg cccctccaac agccgctccc ctgcagaggc gtctcccatc
      901 tgcacctgtc ggaccggtta ttaccgagcg gactttgacc ctccagaagt ggcatgcact
      961 agcgtcccat caggtccccg caatgttatc tccatcgtca atgagacgtc catcattctg
     1021 gagtggcacc ctccaaggga gacaggtggg cgggatgatg tgacctacaa catcatctgc
     1081 aaaaagtgcc gggcagaccg ccggagctgc tcccgctgtg acgacaatgt ggagtttgtg
     1141 cccaggcagc tgggcctgac ggagtgccgc gtctccatca gcagcctgtg ggcccacacc
     1201 ccctacacct ttgacatcca ggccatcaat ggagtctcca gcaagagtcc cttcccccca
     1261 cagcacgtct ctgtcaacat caccacaaac caagccgccc cctccaccgt tcccatcatg
     1321 caccaagtca gtgccactat gaggagcatc accttgtcat ggccacagcc ggagcagccc
     1381 aatggcatca tcctggacta tgagatccgg tactatgaga aggaacacaa tgagttcaac
     1441 tcctccatgg ccaggagtca gaccaacaca gcaaggattg atgggctgcg gcctggcatg
     1501 gtatatgtgg tacaggtgcg tgcccgcact gttgctggct acggcaagtt cagtggcaag
     1561 atgtgcttcc agactctgac tgacgatgat tacaagtcag agctgaggga gcagctgccc
     1621 ctgattgctg gctcggcagc ggccggggtc gtgttcgttg tgtccttggt ggccatctct
     1681 atcgtctgta gcaggaaacg ggcttatagc aaagaggctg tgtacagcga taagctccag
     1741 cattacagca caggccgagg ctccccaggg atgaagatct acattgaccc cttcacttac
     1801 gaggatccca acgaagctgt ccgggagttt gccaaggaga ttgatgtatc ttttgtgaaa
     1861 attgaagagg tcatcggagc aggggagttt ggagaagtgt acaaggggcg tttgaaactg
     1921 ccaggcaaga gggaaatcta cgtggccatc aagaccctga aggcagggta ctcggagaag
     1981 cagcgtcggg actttctgag tgaggcgagc atcatgggcc agttcgacca tcctaacatc
     2041 attcgcctgg agggtgtggt caccaagagt cggcctgtca tgatcatcac agagttcatg
     2101 gagaatggtg cattggattc tttcctcagg caaaatgacg ggcagttcac cgtgatccag
     2161 cttgtgggta tgctcagggg catcgctgct ggcatgaagt acctggctga gatgaattat
     2221 gtgcatcggg acctggctgc taggaacatt ctggtcaaca gtaacctggt gtgcaaggtg
     2281 tccgactttg gcctctcccg ctacctccag gatgacacct cagatcccac ctacaccagc
     2341 tccttgggag ggaagatccc tgtgagatgg acagctccag aggccatcgc ctaccgcaag
     2401 ttcacttcag ccagcgacgt ttggagctat gggatcgtca tgtgggaagt catgtcattt
     2461 ggagagagac cctattggga tatgtccaac caagatgtca tcaatgccat cgagcaggac
     2521 taccggctgc ccccacccat ggactgtcca gctgctctac accagctcat gctggactgt
     2581 tggcagaagg accggaacag ccggccccgg tttgcggaga ttgtcaacac cctagataag
     2641 atgatccgga acccggcaag tctcaagact gtggcaacca tcaccgccgt gccttcccag
     2701 cccctgctcg accgctccat cccagacttc acggccttta ccaccgtgga tgactggctc
     2761 agcgccatca aaatggtcca gtacagggac agcttcctca ctgctggctt cacctccctc
     2821 cagctggtca cccagatgac atcagaagac ctcctgagaa taggcatcac cttggcaggc
     2881 catcagaaga agatcctgaa cagcattcat tctatgaggg tccagataag tcagtcacca
     2941 acggcaatgg ca
//
