LOCUS       sequence-11253-e        1629 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1629)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1629)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-YES1
FEATURES             Location/Qualifiers
     source          1..1629
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgggctgca ttaaaagtaa agaaaacaaa agtccagcca ttaaatacag acctgaaaat
       61 actccagagc ctgtcagtac aagtgtgagc cattatggag cagaacccac tacagtgtca
      121 ccatgtccgt catcttcagc aaagggaaca gcagttaatt tcagcagtct ttccatgaca
      181 ccatttggag gatcctcagg ggtaacgcct tttggaggtg catcttcctc attttcagtg
      241 gtgccaagtt catatcctgc tggtttaaca ggtggtgtta ctatatttgt ggccttatat
      301 gattatgaag ctagaactac agaagacctt tcatttaaga agggtgaaag atttcaaata
      361 attaacaata cggaaggaga ttggtgggaa gcaagatcaa tcgctacagg aaagaatggt
      421 tatatcccga gcaattatgt agcgcctgca gattccattc aggcagaaga atggtatttt
      481 ggcaaaatgg ggagaaaaga tgctgaaaga ttacttttga atcctggaaa tcaacgaggt
      541 attttcttag taagagagag tgaaacaact aaaggtgctt attccctttc tattcgtgat
      601 tgggatgaga taaggggtga caatgtgaaa cactacaaaa ttaggaaact tgacaatggt
      661 ggatactata tcacaaccag agcacaattt gatactctgc agaaattggt gaaacactac
      721 acagaacatg ctgatggttt atgccacaag ttgacaactg tgtgtccaac tgtgaaacct
      781 cagactcaag gtctagcaaa agatgcttgg gaaatccctc gagaatcttt gcgactagag
      841 gttaaactag gacaaggatg tttcggcgaa gtgtggatgg gaacatggaa tggaaccacg
      901 aaagtagcaa tcaaaacact aaaaccaggt acaatgatgc cagaagcttt ccttcaagaa
      961 gctcagataa tgaaaaaatt aagacatgat aaacttgttc cactatatgc tgttgtttct
     1021 gaagaaccaa tttacattgt cactgaattt atgtcaaaag gaagcttatt agatttcctt
     1081 aaggaaggag atggaaagta tttgaagctt ccacagctgg ttgatatggc tgctcagatt
     1141 gctgatggta tggcatatat tgaaagaatg aactatattc accgagatct tcgggctgct
     1201 aatattcttg taggagaaaa tcttgtgtgc aaaatagcag actttggttt agcaaggtta
     1261 attgaagaca atgaatacac agcaagacaa ggtgcaaaat ttccaatcaa atggacagct
     1321 cctgaagctg cactgtatgg tcggtttaca ataaagtctg atgtctggtc atttggaatt
     1381 ctgcaaacag aactagtaac aaagggccga gtgccatatc caggtatggt gaaccgtgaa
     1441 gtactagaac aagtggagcg aggatacagg atgccgtgcc ctcagggctg tccagaatcc
     1501 ctccatgaat tgatgaatct gtgttggaag aaggaccctg atgaaagacc aacatttgaa
     1561 tatattcagt ccttcttgga agactacttc actgctacag agccacagta ccagccagga
     1621 gaaaattta
//
