LOCUS       sequence-11258-e        3372 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3372)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 3372)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-JAK3
FEATURES             Location/Qualifiers
     source          1..3372
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcacctc caagtgaaga gacgcccctg atccctcagc gttcatgcag cctcttgtcc
       61 acggaggctg gtgccctgca tgtgctgctg cccgctcggg gccccgggcc cccccagcgc
      121 ctatctttct cctttgggga ccacttggct gaggacctgt gcgtgcaggc tgccaaggcc
      181 agcggcatcc tgcctgtgta ccactccctc tttgctctgg ccacggagga cctgtcctgc
      241 tggttccccc cgagccacat cttctccgtg gaggatgcca gcacccaagt cctgctgtac
      301 aggattcgct tttacttccc caattggttt gggctggaga agtgccaccg cttcgggcta
      361 cgcaaggatt tggccagtgc tatccttgac ctgccagtcc tggagcacct ctttgcccag
      421 caccgcagtg acctggtgag tgggcgcctc cccgtgggcc tcagtctcaa ggagcagggt
      481 gagtgtctca gcctggccgt gttggacctg gcccggatgg cgcgagagca ggcccagcgg
      541 ccgggagagc tgctgaagac tgtcagctac aaggcctgcc tacccccaag cctgcgcgac
      601 ctgatccagg gcctgagctt cgtgacgcgg aggcgtattc ggaggacggt gcgcagagcc
      661 ctgcgccgcg tggccgcctg ccaggcagac cggcactcgc tcatggccaa gtacatcatg
      721 gacctggagc ggctggatcc agccggggcc gccgagacct tccacgtggg cctccctggg
      781 gcccttggtg gccacgacgg gctggggctg ctccgcgtgg ctggtgacgg cggcatcgcc
      841 tggacccagg gagaacagga ggtcctccag cccttctgcg actttccaga aatcgtagac
      901 attagcatca agcaggcccc gcgcgttggc ccggccggag agcaccgcct ggtcactgtt
      961 accaggacag acaaccagat tttagaggcc gagttcccag ggctgcccga ggctctgtcg
     1021 ttcgtggcgc tcgtggacgg ctacttccgg ctgaccacgg actcccagca cttcttctgc
     1081 aaggaggtgg caccgccgag gctgctggag gaagtggccg agcagtgcca cggccccatc
     1141 actctggact ttgccatcaa caagctcaag actgggggct cacgtcctgg ctcctatgtt
     1201 ctccgccgca gcccccagga ctttgacagc ttcctcctca ctgtctgtgt ccagaacccc
     1261 cttggtcctg attataaggg ctgcctcatc cggcgcagcc ccacaggaac cttccttctg
     1321 gttggcctca gccgacccca cagcagtctt cgagagctcc tggcaacctg ctgggatggg
     1381 gggctgcacg tagatggggt ggcagtgacc ctcacttcct gctgtatccc cagacccaaa
     1441 gaaaagtcca acctgatcgt ggtccagaga ggtcacagcc cacccacatc atccttggtt
     1501 cagccccaat cccaatacca gctgagtcag atgacatttc acaagatccc tgctgacagc
     1561 ctggagtggc atgagaacct gggccatggg tccttcacca agatttaccg gggctgtcgc
     1621 catgaggtgg tggatgggga ggcccgaaag acagaggtgc tgctgaaggt catggatgcc
     1681 aagcacaaga actgcatgga gtcattcctg gaagcagcga gcttgatgag ccaagtgtcg
     1741 taccggcatc tcgtgctgct ccacggcgtg tgcatggctg gagacagcac catggtgcag
     1801 gaatttgtac acctgggggc catagacatg tatctgcgaa aacgtggcca cctggtgcca
     1861 gccagctgga agctgcaggt ggtcaaacag ctggcctacg ccctcaacta tctggaggac
     1921 aaaggcctgc cccatggcaa tgtctctgcc cggaaggtgc tcctggctcg ggagggggct
     1981 gatgggagcc cgcccttcat caagctgagt gaccctgggg tcagccccgc tgtgttaagc
     2041 ctggagatgc tcaccgacag gatcccctgg gtggcccccg agtgtctccg ggaggcgcag
     2101 acacttagct tggaagctga caagtggggc ttcggcgcca cggtctggga agtgtttagt
     2161 ggcgtcacca tgcccatcag tgccctggat cctgctaaga aactccaatt ttatgaggac
     2221 cggcagcagc tgccggcccc caagtggaca gagctggccc tgctgattca acagtgcatg
     2281 gcctatgagc cggtccagag gccctccttc cgagccgtca ttcgtgacct caatagcctc
     2341 atctcttcag actatgagct cctctcagac cccacacctg gtgccctggc acctcgtgat
     2401 gggctgtgga atggtgccca gctctatgcc tgccaagacc ccacgatctt cgaggagaga
     2461 cacctcaagt acatctcaca gctgggcaag ggcaactttg gcagcgtgga gctgtgccgc
     2521 tatgacccgc taggcgacaa tacaggtgcc ctggtggccg tgaaacagct gcagcacagc
     2581 gggccagacc agcagaggga ctttcagcgg gagattcaga tcctcaaagc actgcacagt
     2641 gatttcattg tcaagtatcg tggtgtcagc tatggcccgg gccgccagag cctgcggctg
     2701 gtcatggagt acctgcccag cggctgcttg cgcgacttcc tgcagcggca ccgcgcgcgc
     2761 ctcgatgcca gccgcctcct tctctattcc tcgcagatct gcaagggcat ggagtacctg
     2821 ggctcccgcc gctgcgtgca ccgcgacctg gccgcccgaa acatcctcgt ggagagcgag
     2881 gcacacgtca agatcgctga cttcggccta gctaagctgc tgccgcttga caaagactac
     2941 tacgtggtcc gcgagccagg ccagagcccc attttctggt atgcccccga atccctctcg
     3001 gacaacatct tctctcgcca gtcagacgtc tggagcttcg gggtcgtcct gtacgagctc
     3061 ttcacctact gcgacaaaag ctgcagcccc tcggccgagt tcctgcggat gatgggatgt
     3121 gagcgggatg tccccgccct ctgccgcctc ttggaactgc tggaggaggg ccagaggctg
     3181 ccggcgcctc ctgcctgccc tgctgaggtt cacgagctca tgaagctgtg ctgggcccct
     3241 agcccacagg accggccatc attcagcgcc ctgggccccc agctggacat gctgtggagc
     3301 ggaagccggg ggtgtgagac tcatgccttc actgctcacc cagagggcaa acaccactcc
     3361 ctgtcctttt ca
//
