LOCUS       sequence-119780-         656 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expression of P. falciparum dihydropteroate synthase.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 656)
  AUTHORS   Stratton CF, Namanja-Magliano HA, Cameron SA, Schramm VL
  TITLE     Binding Isotope Effects for para-Aminobenzoic Acid with 
            Dihydropteroate Synthase from Staphylococcus aureus and Plasmodium 
            falciparum.
  JOURNAL   ACS Chem Biol. 2015 Oct 16;10(10):2182-6. doi: 
            10.1021/acschembio.5b00490. Epub 2015 Aug 27.
  PUBMED    26288086
REFERENCE   2  (bases 1 to 656)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acschembio.5b00490"; journalName: "ACS Chem Biol"; date: 
            "2015-10-16- 16"; volume: "10"; issue: "10"; pages: "2182-6"
COMMENT     Sequence Label: P. falciparum  DHPS
FEATURES             Location/Qualifiers
     source          1..656
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    12..28
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     protein_bind    42..61
                     /label=lac operator (symmetric)
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG). The 
                     symmetric lac operator was optimized for tight binding of 
                     lac repressor."
ORIGIN
        1 atttatttgc tttgtgagcg gataacaatt ataatatgtg gaattgtgag cgctcacaat
       61 tccacaacgg tttccctcta gaaataattt tgtttaactt ttaggaggta aaacatatgg
      121 agactattca agaactgatt ctgagcgaag agaacaaaac gaatattgcg gtgctgaatt
      181 tgggcacgaa tgaccgccgt aacgcggttc tgatcctgga aacggccctg cacctggtgg
      241 agaagtacct gggtaagatt atcaacacca gctacctgta tgagactgtc ccggagtata
      301 ttgtcttgga caagaaagag agctgtgaaa agatcaataa agactgccgc atctacgatg
      361 tcaactatat caatgagctg atgcaaaatc tggaagaaag caagtatgaa gagaataaag
      421 agctgattga taagtgcgaa gaatacgaaa cctttctgaa gaatggcaag gttgataata
      481 gcatcctgaa agaggtcaac gtcgagaact acttgctgga gtgcaataac atcatcgtca
      541 aaaacgatga aatcatgaaa aacaacctga gcaagtacaa agacaaatac tatacgtctt
      601 acttttacaa tctgaccgtc gtggtgaaaa ccttcgttaa tgatccgctg agcatg
//
