LOCUS       sequence-120860-        1732 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  4-hydroxytamoxifen inducible ER:ras fusion protein.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1732)
  AUTHORS   Young AR, Narita M, Ferreira M, Kirschner K, Sadaie M, Darot JF, 
            Tavare S, Arakawa S, Shimizu S, Watt FM, Narita M
  TITLE     Autophagy mediates the mitotic senescence transition.
  JOURNAL   Genes Dev. 2009 Apr 1;23(7):798-803. doi: 10.1101/gad.519709. Epub 
            2009 Mar 11.
  PUBMED    19279323
REFERENCE   2  (bases 1 to 1732)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1101/gad.519709"; journalName: "Genes Dev"; date: "2009-04-1- 
            1"; volume: "23"; issue: "7"; pages: "798-803"
COMMENT     Sequence Label: pLNCX2 ER:ras
FEATURES             Location/Qualifiers
     source          1..1732
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             join(1079..1111,1112..1114,1115..1648)
                     /codon_start=1
                     /product="human oncoprotein generated by the G12V mutation 
                     in the small GTPase H-Ras"
                     /label=H-Ras (G12V)
                     /translation="MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVV
                     IDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVK
                     DSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI
                     RQHKLRKLNPPDESGPGCMSCKCVLS"
ORIGIN
        1 gtcngatcgc ctggagacgc catccacgct gttttgacct ccatagaaga caccgggacc
       61 gatccagcct ccgcggcccc aagcttgttg atccaccatg cgaaatgaaa tgggtgcttc
      121 aggagacatg agggctgcca acctttggcc aagccctctt gtgattaagc acactaagaa
      181 gaatagccct gccttgtcct tgacagctga ccagatggtc agtgccttgt tggatgctga
      241 accgcccatg atctattctg aatatgatcc ttctagaccc ttcagtgaag cctcaatgat
      301 gggcttattg accaacctag cagataggga gctggttcat atgatcaact gggcaaagag
      361 agtgccaggc tttggggact tgaatctcca tgatcaggtc caccttctcg agtgtgcctg
      421 gctggagatt ctgatgattg gtctcgtctg gcgctccatg gaacacccgg ggaagctcct
      481 gtttgctcct aacttgctcc tggacaggaa tcaaggtaaa tgtgtggaag gcatggtgga
      541 gatctttgac atgttgcttg ctacgtcaag tcggttccgc atgatgaacc tgcagggtga
      601 agagtttgtg tgcctcaaat ccatcatttt gcttaattcc ggagtgtaca cgtttctgtc
      661 cagcaccttg aagtctctgg aagagaagga ccacatccac cgtgtcctgg acaagatcac
      721 agacactttg atccacctga tggccaaagc tggcctgact ctgcagcagc agcatcgccg
      781 cctagctcag ctccttctca ttctttccca tatccggcat atgagtaaca aacgcatgga
      841 gcatctctac aacatgaaat gcaagaacgt ggtacccctc tatgacctgc tcctggagat
      901 gttggatgcc caccgccttc atgccccagc cagtcgcatg ggagtgcccc cagaggagcc
      961 cagccagacc cagctggcca ccaccagctc cacttcagca cattccttac aaacctacta
     1021 catacccccg gaagcagagg gcttccccaa cgatatccca cgtggaggcc tgaattccat
     1081 gacggaatat aagctggtgg tggtgggcgc cgtcggtgtg ggcaagagtg cgctgaccat
     1141 ccagctgatc cagaaccatt ttgtggacga atacgacccc actatagagg attcctaccg
     1201 gaagcaggtg gtcattgatg gggagacgtg cctgttggac atcctggata ccgccggcca
     1261 ggaggagtac agcgccatgc gggaccagta catgcgcacc ggggagggct tcctgtgtgt
     1321 gtttgccatc aacaacacca agtcttttga ggacatccac cagtacaggg agcagatcaa
     1381 acgggtgaag gactcggatg acgtgcccat ggtgctggtg gggaacaagt gtgacctggc
     1441 tgcacgcact gtggaatctc ggcaggctca ggacctcgcc cgaagctacg gcatccccta
     1501 catcgagacc tcggccaaga cccggcaggg agtggaggat gccttctaca cgttggtgcg
     1561 tgagatccgg cagcacaagc tgcggaagct gaaccctcct gatgagagtg gccccggctg
     1621 catgagctgc aagtgtgtgc tctcctgacg caattcgata tcaagcttga attcccgcgg
     1681 gcggccaaca tcgataaaat aaaagattat nnnctgtata ggtcntangc nc
//
