LOCUS       sequence-120882-         976 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  4-hydroxytamoxifen inducible ER:ras fusion protein.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 976)
  AUTHORS   Young AR, Narita M, Ferreira M, Kirschner K, Sadaie M, Darot JF, 
            Tavare S, Arakawa S, Shimizu S, Watt FM, Narita M
  TITLE     Autophagy mediates the mitotic senescence transition.
  JOURNAL   Genes Dev. 2009 Apr 1;23(7):798-803. doi: 10.1101/gad.519709. Epub 
            2009 Mar 11.
  PUBMED    19279323
REFERENCE   2  (bases 1 to 976)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1101/gad.519709"; journalName: "Genes Dev"; date: "2009-04-1- 
            1"; volume: "23"; issue: "7"; pages: "798-803"
COMMENT     Sequence Label: pLNCX2 ER:ras
FEATURES             Location/Qualifiers
     source          1..976
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             complement(join(71..604,605..607,608..640))
                     /codon_start=1
                     /product="human oncoprotein generated by the G12V mutation 
                     in the small GTPase H-Ras"
                     /label=H-Ras (G12V)
                     /translation="MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVV
                     IDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVK
                     DSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI
                     RQHKLRKLNPPDESGPGCMSCKCVLS"
ORIGIN
        1 tcgatgttag gccattaagg cctgtcgaca agcggccgcc tcggccaaac aagcttgata
       61 tcgaattgcg tcaggagagc acacacttgc agctcatgca gccggggcca ctctcatcag
      121 gagggttcag cttccgcagc ttgtgctgcc ggatctcacg caccaacgtg tagaaggcat
      181 cctccactcc ctgccgggtc ttggccgagg tctcgatgta ggggatgccg tagcttcggg
      241 cgaggtcctg agcctgccga gattccacag tgcgtgcagc caggtcacac ttgttcccca
      301 ccagcaccat gggcacgtca tccgagtcct tcacccgttt gatctgctcc ctgtactggt
      361 ggatgtcctc aaaagacttg gtgttgttga tggcaaacac acacaggaag ccctccccgg
      421 tgcgcatgta ctggtcccgc atggcgctgt actcctcctg gccggcggta tccaggatgt
      481 ccaacaggca cgtctcccca tcaatgacca cctgcttccg gtaggaatcc tctatagtgg
      541 ggtcgtattc gtccacaaaa tggttctgga tcagctggat ggtcagcgca ctcttgccca
      601 caccgacggc gcccaccacc accagcttat attccgtcat ggaattcagg cctccacgtg
      661 ggatatcgtt ggggaagccc tctgcttccg ggggtatgta gtaggtttgt aaggaatgtg
      721 ctgaagtgga gctggtggtg gccagctggg tctggctggg ctcctctggg ggcactccca
      781 tgcgactggc tggggcatga aggcggtggg catccaacat ctccaggagc aggtcataga
      841 ggggtaccac gttcttgcat ttcatgttgt agagatgctc catgcgtttg ttactcatat
      901 gccggatatg ggaaagaatg agaaggagct gagctaggcg gcgatgctgc tgctgcagag
      961 tcaggccagc tttggc
//
