LOCUS       sequence-131106-         746 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  encodes the lamin A mutant with a 50 amino acids deletion 
            responsible for the Hutchinson-Gilford Progeria Syndrome.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Moiseeva O, Lessard F, Acevedo-Aquino M, Vernier M, Tsantrizos YS, 
            Ferbeyre G
  TITLE     Mutant lamin A links prophase to a p53 independent senescence 
            program.
  JOURNAL   Cell Cycle. 2015 Aug 3;14(15):2408-21. doi: 
            10.1080/15384101.2015.1053671. Epub 2015 Jun 1.
  PUBMED    26029982
REFERENCE   2  (bases 1 to 746)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1080/15384101.2015.1053671"; journalName: "Cell Cycle"; date: 
            "2015-08-3- 3"; volume: "14"; issue: "15"; pages: "2408-21"
COMMENT     Sequence Label: pLPC-Progerin
FEATURES             Location/Qualifiers
     source          1..746
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     34..50
                     /label=pBluescriptKS
                     /note="For pBluescript vector"
     primer_bind     35..51
                     /label=KS primer
                     /note="common sequencing primer, one of multiple similar 
                     variants"
ORIGIN
        1 atcttttatt ttatcggccc tctagatgca tgctcgaggt cgacggtatc gataagcttg
       61 atatcgaatt cttacatgat gctgcagttc tgggggctct gggctcctga gccgctggca
      121 gatgccttgt cggcaggctg cccgcaggtc ccgcacagca cggtgcgcga gcgcaggttg
      181 tactcagcgg ggtcccccga gctgctgcag tgggagccgt ggtggtgatg gagcaggtca
      241 tctccatcct catcctcgtc gtcctcaacc acagtcactg agcgcaccag cttgcgcatg
      301 gccacttctt ccccagtgga gttgatgaga gccgtacgca ggctgttccc gcagccccag
      361 gtgttctgtg ccttccacac caggtcggta ggggggctgt gggtggcccc agctcctgca
      421 gcccagatcg tcaccacctg cccagccttc agggtgaact ttggtgggaa ccggtaagtc
      481 agcaagggat catctccatt ctggcgcttg atctgccaat tgcccatgga ctggtcctca
      541 ttggacttgt tgcgcagccg gacaaacttg ccctcctcat ccacctcctc cacggccacg
      601 cgcccgctag tgcgtgcgtg ctgtgagaag ctgctgcggc tctcagtgga ctccagtttg
      661 cgctttttgg tgacgctgcc cccaccctgt gtctgggatg agtgagagga agcacggcca
      721 cggctgcgct gcgaggtagg gctggg
//
