LOCUS       sequence-131587-         820 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  encodes a Progerin mutant with serine 22 mutated to an alanine and 
            with a substitution of cysteine in CaaX-motif by a serine.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 820)
  AUTHORS   Moiseeva O, Lessard F, Acevedo-Aquino M, Vernier M, Tsantrizos YS, 
            Ferbeyre G
  TITLE     Mutant lamin A links prophase to a p53 independent senescence 
            program.
  JOURNAL   Cell Cycle. 2015 Aug 3;14(15):2408-21. doi: 
            10.1080/15384101.2015.1053671. Epub 2015 Jun 1.
  PUBMED    26029982
REFERENCE   2  (bases 1 to 820)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1080/15384101.2015.1053671"; journalName: "Cell Cycle"; date: 
            "2015-08-3- 3"; volume: "14"; issue: "15"; pages: "2408-21"
COMMENT     Sequence Label: pLPC-S22AProgerin-CS
FEATURES             Location/Qualifiers
     source          1..820
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     21..40
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        21..39
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
ORIGIN
        1 gcttactggc ttatcgaaat taatacgact cactataggg agacccaagc ttggtaccga
       61 gctcggatcc accatggaga ccccgtccca gcggcgcgcc acccgcagcg gggcgcaggc
      121 cagctccact ccgctggcac ccacccgcat cacccggctg caggagaagg aggacctgca
      181 ggagctcaat gatcgcttgg cggtctacat cgaccgtgtg cgctcgctgg aaacggagaa
      241 cgcagggctg cgccttcgca tcaccgagtc tgaagaggtg gtcagccgcg aggtgtccgg
      301 catcaaggcc gcctacgagg ccgagctcgg ggatgcccgc aagacccttg actcagtagc
      361 caaggagcgc gcccgcctgc agctggagct gagcaaagtg cgtgaggagt ttaaggagct
      421 gaaagcgcgc aataccaaga aggagggtga cctgatagct gctcaggctc ggctgaagga
      481 cctggaggct ctgctgaact ccaaggaggc cgcactgagc actgctctca gtgagaagcg
      541 cacgctggag ggcgagctgc atgatctgcg gggccaggtg gccaagcttg aggcagccct
      601 aggtgaggcc aagaagcaac ttcaggatga gatgctgcgg cgggtggatg ctgagaacag
      661 gctgcagacc atgaaggagg aactggactt ccagaagaac atctacagtg aggagctgcg
      721 tgagaccaag cgccgtcatg agacccgact ggtggagatt gacaatggga agcagcgtga
      781 gtttgagagc cggctggcgg atgcgctgca ggaactgcgg
//
