LOCUS       sequence-132862-        1061 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  activating MTOR mutation.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Grabiner BC, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, Jordan
            A, Beck AH, Sabatini DM
  TITLE     A diverse array of cancer-associated MTOR mutations are 
            hyperactivating and can predict rapamycin sensitivity.
  JOURNAL   Cancer Discov. 2014 May;4(5):554-63. doi: 
            10.1158/2159-8290.CD-13-0929. Epub 2014 Mar 14.
  PUBMED    24631838
REFERENCE   2  (bases 1 to 1061)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/2159-8290.CD-13-0929"; journalName: "Cancer Discov"; date: 
            "2014-05"; volume: "4"; issue: "5"; pages: "554-63"
COMMENT     Sequence Label: pcDNA3-FLAG-MTOR-F1888L
FEATURES             Location/Qualifiers
     source          1..1061
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 gagagagctg ccaagtgccg agcatatgcc aaagcactac actacaaaga actggagttc
       61 cagaaaggcc ccacccctgc cattctagaa tctctcatca gcattaataa taagctacag
      121 cagccggagg cagcggccgg agtgttagaa tatgccatga aacactttgg agagctggag
      181 atccaggcta cctggtatga gaaactgcac gagtgggagg atgcccttgt ggcctatgac
      241 aagaaaatgg acaccaacaa ggacgaccca gagctgatgc tgggccgcat gcgctgcctc
      301 gaggccttgg gggaatgggg tcaactccac cagcagtgct gtgaaaagtg gaccctggtt
      361 aatgatgaga cccaagccaa gatggcccgg atggctgctg cagctgcatg gggtttaggt
      421 cagtgggaca gcatggaaga atacacctgt atgatccctc gggacaccca tgatggggca
      481 ttttatagag ctgtgctggc actgcatcag gacctcttct ccttggcaca acagtgcatt
      541 gacaaggcca gggacctgct ggatgctgaa ttaactgcaa tggcaggaga gagttacagt
      601 cgggcatatg gggccatggt ttcttgccac atgctgtccg agctggagga ggttatccag
      661 tacaaacttg tccccgagcg acgagagatc atccgccaga tctggtggga gagactgcag
      721 ggctgccagc gtatcgtaga ggactggcag aaaatcctta tggtgcggtc ccttgtggtc
      781 agccctcatg aagacatgag aacctggctc aagtatgcaa gcctgtgcgg caagagtggc
      841 aggctggctc ttgctcataa aactttagtg ttgctcctgg gagttgatcc gtctcggcaa
      901 cttgaccatc ctctgccaac agttcaccct caggtgacct atgcctacat gaaaaacatg
      961 tggaagagtg cccgcaagat cgatgccttc cagcacatgc agcattttgt ccagaccatg
     1021 cagcaacagg cccagcatgc catcgctact gaggaccagc a
//
