LOCUS       sequence-132863-         792 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  encodes the lamin A mutant with a 50 amino acids deletion 
            responsible for the Hutchinson-Gilford Progeria Syndrome.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Moiseeva O, Lessard F, Acevedo-Aquino M, Vernier M, Tsantrizos YS, 
            Ferbeyre G
  TITLE     Mutant lamin A links prophase to a p53 independent senescence 
            program.
  JOURNAL   Cell Cycle. 2015 Aug 3;14(15):2408-21. doi: 
            10.1080/15384101.2015.1053671. Epub 2015 Jun 1.
  PUBMED    26029982
REFERENCE   2  (bases 1 to 792)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1080/15384101.2015.1053671"; journalName: "Cell Cycle"; date: 
            "2015-08-3- 3"; volume: "14"; issue: "15"; pages: "2408-21"
COMMENT     Sequence Label: pLPC-Progerin
FEATURES             Location/Qualifiers
     source          1..792
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     3..22
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        3..21
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
ORIGIN
        1 attaatacga ctcactatag ggagacccaa gcttggtacc gagctcggat ccaccatgga
       61 gaccccgtcc cagcggcgcg ccacccgcag cggggcgcag gccagctcca ctccgctgtc
      121 gcccacccgc atcacccggc tgcaggagaa ggaggacctg caggagctca atgatcgctt
      181 ggcggtctac atcgaccgtg tgcgctcgct ggaaacggag aacgcagggc tgcgccttcg
      241 catcaccgag tctgaagagg tggtcagccg cgaggtgtcc ggcatcaagg ccgcctacga
      301 ggccgagctc ggggatgccc gcaagaccct tgactcagta gccaaggagc gcgcccgcct
      361 gcagctggag ctgagcaaag tgcgtgagga gtttaaggag ctgaaagcgc gcaataccaa
      421 gaaggagggt gacctgatag ctgctcaggc tcggctgaag gacctggagg ctctgctgaa
      481 ctccaaggag gccgcactga gcactgctct cagtgagaag cgcacgctgg agggcgagct
      541 gcatgatctg cggggccagg tggccaagct tgaggcagcc ctaggtgagg ccaagaagca
      601 acttcaggat gagatgctgc ggcgggtgga tgctgagaac aggctgcaga ccatgaagga
      661 ggaactggac ttccagaaga acatctacag tgaggagctg cgtgagacca agcgccgtca
      721 tgagacccga ctggtggaga ttgacaatgg gaagcagcgt gagtttgaga gccggctggc
      781 ggatgcgctg ca
//
