LOCUS       sequence-132869-        1061 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  activating MTOR mutation.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Grabiner BC, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, Jordan
            A, Beck AH, Sabatini DM
  TITLE     A diverse array of cancer-associated MTOR mutations are 
            hyperactivating and can predict rapamycin sensitivity.
  JOURNAL   Cancer Discov. 2014 May;4(5):554-63. doi: 
            10.1158/2159-8290.CD-13-0929. Epub 2014 Mar 14.
  PUBMED    24631838
REFERENCE   2  (bases 1 to 1061)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/2159-8290.CD-13-0929"; journalName: "Cancer Discov"; date: 
            "2014-05"; volume: "4"; issue: "5"; pages: "554-63"
COMMENT     Sequence Label: pcDNA3-FLAG-MTOR-T1977R
FEATURES             Location/Qualifiers
     source          1..1061
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     42..58
                     /label=SK primer
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     42..58
                     /label=pBluescriptSK
                     /note="For pBluescript vector"
ORIGIN
        1 ctatagaata gggccctcta gatgcatgct cgagcggccg ctctagaact agtggatccc
       61 ccatttaaca aagtcaaact ttctcaccat ggtttcagtt tagtggaagc atttactaaa
      121 gtacaaaagc ctcagaaaaa acgtgatggg cacatctggg cctccagtta ccagaaaggg
      181 caccagccaa tatagcactg gcagaggttt tcatgggatg tcgcttgttt gatgagcagc
      241 tcaacttgcg ttggaacatc caaagtgtca tcatgagaga agtcccgacc agtgagctta
      301 tctcgaaccc tgttaataat ctggatagct ttcttattta gggcctctgg tttcaccaaa
      361 ccgtctccaa tgaaagaatg aatagattct ggcactgtgg tccccgtttt cttatgggct
      421 ggctctccaa gttccacacc gtccaaaatt tcgactgact ggccagcaga gtaggaatcc
      481 gtcctcgttc gggatcgctt gttgcctttg gtatttgtgt ccatcagcct ccagttcagc
      541 aaggggtcat agacaaaggc ttccagcacg gccatgacac tgtccttgtg ctctcgcagc
      601 acctccatca ctgtgtggca tgtgattctg tagttgccat ccaggcctgt aacctccata
      661 gcattggtca acattcttgt tagtctaaat ggaatcttct ctggaaactt ctctcgggtc
      721 atagcaacct caaagcagtc cccaaagtca atgtgcagga tcttcccact cagacggtcc
      781 agcatcaggt tggatgggtg tctatctccc aggcctaaaa tatacccaac cattgacatg
      841 accgctaaag aacgggtata attggttctt cggtcaaacc acacctcgga gctggggctt
      901 ttcagccaca gcagcttggc caggtcgtcc ccagctgtat tattgacggc atgctcaaac
      961 acctccacct tctgcatcag agtcaagtgg tcatagtccg gagccatccg caacatgatg
     1021 cgatgctcga tgttgagaag gatcttcttc ttctccctgt a
//
