LOCUS       sequence-132938-        1071 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  activating MTOR mutation.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1071)
  AUTHORS   Grabiner BC, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, Jordan
            A, Beck AH, Sabatini DM
  TITLE     A diverse array of cancer-associated MTOR mutations are 
            hyperactivating and can predict rapamycin sensitivity.
  JOURNAL   Cancer Discov. 2014 May;4(5):554-63. doi: 
            10.1158/2159-8290.CD-13-0929. Epub 2014 Mar 14.
  PUBMED    24631838
REFERENCE   2  (bases 1 to 1071)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/2159-8290.CD-13-0929"; journalName: "Cancer Discov"; date: 
            "2014-05"; volume: "4"; issue: "5"; pages: "554-63"
COMMENT     Sequence Label: pcDNA3-FLAG-MTOR-V2006I
FEATURES             Location/Qualifiers
     source          1..1071
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     52..68
                     /label=SK primer
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     52..68
                     /label=pBluescriptSK
                     /note="For pBluescript vector"
ORIGIN
        1 ttaggtgaca ctatagaata gggccctcta gatgcatgct cgagcggccg ctctagaact
       61 agtggatccc ccatttaaca aagtcaaact ttctcaccat ggtttcagtt tagtggaagc
      121 atttactaaa gtacaaaagc ctcagaaaaa acgtgatggg cacatctggg cctccagtta
      181 ccagaaaggg caccagccaa tatagcactg gcagaggttt tcatgggatg tcgcttgttt
      241 gatgagcagc tcaacttgcg ttggaacatc caaagtgtca tcatgagaga agtcccgacc
      301 agtgagctta tctcgaaccc tgttaataat ctggatagct ttcttattta gggcctctgg
      361 tttcaccaaa ccgtctccaa tgaaagaatg aatagattct ggcactgtgg tccccgtttt
      421 cttatgggct ggctctccaa gttccacacc gtccaaaatt tcgactgact ggccagcaga
      481 gtaggaatcc gtcctcgttc gggatcgctt gttgcctttg gtatttgtgt ccatcagcct
      541 ccagttcagc aaggggtcat agacaaaggc ttccagcacg gccatgacac tgtccttgtg
      601 ctctcgcagc acctccatca ctgtgtggca tgtgattctg tagttgccat ccaggcctgt
      661 aacctccata gcattggtca acattcttgt tagtctaaat ggaatcttct ctggaaactt
      721 ctctcgggtc atagcaacct caaagcagtc cccaaagtca atgtgcagga tcttcccact
      781 cagacggtcc agcatcaggt tggatgggtg tctatctccc aggcctaaaa tatacccaac
      841 cattgacatg accgctaaag aacgggtata attggttctt cggtcaaacc acacctcgga
      901 gctggggctt ttcagccaca gcagcttggc caggtcgtcc ccagctgtat tattgacggc
      961 atgctcaaac acctccacct tctgcatcag agtcaagtgg tcatagtccg gagccatccg
     1021 caacatgatg cgatgctcga tgttgagaag gatcttcttc ttctccctgt a
//
