LOCUS       sequence-132982-        1002 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  activating MTOR mutation.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Grabiner BC, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, Jordan
            A, Beck AH, Sabatini DM
  TITLE     A diverse array of cancer-associated MTOR mutations are 
            hyperactivating and can predict rapamycin sensitivity.
  JOURNAL   Cancer Discov. 2014 May;4(5):554-63. doi: 
            10.1158/2159-8290.CD-13-0929. Epub 2014 Mar 14.
  PUBMED    24631838
REFERENCE   2  (bases 1 to 1002)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/2159-8290.CD-13-0929"; journalName: "Cancer Discov"; date: 
            "2014-05"; volume: "4"; issue: "5"; pages: "554-63"
COMMENT     Sequence Label: pcDNA3-FLAG-MTOR-R2505P
FEATURES             Location/Qualifiers
     source          1..1002
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     41..57
                     /label=SK primer
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     41..57
                     /label=pBluescriptSK
                     /note="For pBluescript vector"
ORIGIN
        1 tatagaatag ggccctctag atgcatgctc gagcggccgc tctagaacta gtggatcccc
       61 catttaacaa agtcaaactt tctcaccatg gtttcagttt agtggaagca tttactaaag
      121 tacaaaagcc tcagaaaaaa cgtgatgggc acatctgggc ctccagttac cagaaagggc
      181 accagccaat atagcactgg cagaggtttt catgggatgt cgcttgtttg atgagcagct
      241 caacttgcgt tggaacatcc aaagtgtcat catgagagaa gtcccgacca gtgagcttat
      301 ctggaaccct gttaataatc tggatagctt tcttatttag ggcctctggt ttcaccaaac
      361 cgtctccaat gaaagaatga atagattctg gcactgtggt ccccgttttc ttatgggctg
      421 gctctccaag ttccacaccg tccaaaattt cgactgactg gccagcagag taggaatccg
      481 tcctcgttcg ggatcgcttg ttgcctttgg tatttgtgtc catcagcctc cagttcagca
      541 aggggtcata gacaaaggct tccagcacgg ccatgacact gtccttgtgc tctcgcagca
      601 cctccatcac tgtgtggcat gtgattctgt agttgccatc caggcctgta acctccatag
      661 cattggtcaa cattcttgtt agtctaaatg gaatcttctc tggaaacttc tctcgggtca
      721 tagcaacctc aaagcagtcc ccaaagtcaa tgtgcaggat cttcccactc agacggtcca
      781 gcatcaggtt ggatgggtgt ctatctccca ggcctaaaat atacccaacc attgacatga
      841 ccgctaaaga acgggtataa ttggttcttc ggtcaaacca cacctcggag ctggggcttt
      901 tcagccacag cagcttggcc aggtcgtccc cagctgtatt attgacggca tgctcaaaca
      961 cctccacctt ctgcatcaga gtcaagtggt catagtccgg aa
//
