LOCUS       sequence-133066-         825 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  encodes a Progerin mutant where serine 22 is mutated to an alanine.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 825)
  AUTHORS   Moiseeva O, Lessard F, Acevedo-Aquino M, Vernier M, Tsantrizos YS, 
            Ferbeyre G
  TITLE     Mutant lamin A links prophase to a p53 independent senescence 
            program.
  JOURNAL   Cell Cycle. 2015 Aug 3;14(15):2408-21. doi: 
            10.1080/15384101.2015.1053671. Epub 2015 Jun 1.
  PUBMED    26029982
REFERENCE   2  (bases 1 to 825)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1080/15384101.2015.1053671"; journalName: "Cell Cycle"; date: 
            "2015-08-3- 3"; volume: "14"; issue: "15"; pages: "2408-21"
COMMENT     Sequence Label: pLPC-S22A-Progerin
FEATURES             Location/Qualifiers
     source          1..825
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     26..45
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        26..44
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
ORIGIN
        1 ccactgctta ctggcttatc gaaattaata cgactcacta tagggagacc caagcttggt
       61 accgagctcg gatccaccat ggagaccccg tcccagcggc gcgccacccg cagcggggcg
      121 caggccagct ccactccgct ggcacccacc cgcatcaccc ggctgcagga gaaggaggac
      181 ctgcaggagc tcaatgatcg cttggcggtc tacatcgacc gtgtgcgctc gctggaaacg
      241 gagaacgcag ggctgcgcct tcgcatcacc gagtctgaag aggtggtcag ccgcgaggtg
      301 tccggcatca aggccgccta cgaggccgag ctcggggatg cccgcaagac ccttgactca
      361 gtagccaagg agcgcgcccg cctgcagctg gagctgagca aagtgcgtga ggagtttaag
      421 gagctgaaag cgcgcaatac caagaaggag ggtgacctga tagctgctca ggctcggctg
      481 aaggacctgg aggctctgct gaactccaag gaggccgcac tgagcactgc tctcagtgag
      541 aagcgcacgc tggagggcga gctgcatgat ctgcggggcc aggtggccaa gcttgaggca
      601 gccctaggtg aggccaagaa gcaacttcag gatgagatgc tgcggcgggt ggatgctgag
      661 aacaggctgc agaccatgaa ggaggaactg gacttccaga agaacatcta cagtgaggag
      721 ctgcgtgaga ccaagcgccg tcatgagacc cgactggtgg agattgacaa tgggaagcag
      781 cgtgagtttg agagccggct ggcggatgcg ctgcaggaac tgcgg
//
