LOCUS       sequence-133088-        1091 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  activating MTOR mutation.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Grabiner BC, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, Jordan
            A, Beck AH, Sabatini DM
  TITLE     A diverse array of cancer-associated MTOR mutations are 
            hyperactivating and can predict rapamycin sensitivity.
  JOURNAL   Cancer Discov. 2014 May;4(5):554-63. doi: 
            10.1158/2159-8290.CD-13-0929. Epub 2014 Mar 14.
  PUBMED    24631838
REFERENCE   2  (bases 1 to 1091)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/2159-8290.CD-13-0929"; journalName: "Cancer Discov"; date: 
            "2014-05"; volume: "4"; issue: "5"; pages: "554-63"
COMMENT     Sequence Label: pcDNA3-FLAG-MTOR-L1460P
FEATURES             Location/Qualifiers
     source          1..1091
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 tgagagagct gccaagtgcc gagcatatgc caaagcacta cactacaaag aactggagtt
       61 ccagaaaggc cccacccctg ccattctaga atctctcatc agcattaata ataagctaca
      121 gcagccggag gcagcggccg gagtgttaga atatgccatg aaacactttg gagagctgga
      181 gatccaggct acctggtatg agaaactgca cgagtgggag gatgcccctg tggcctatga
      241 caagaaaatg gacaccaaca aggacgaccc agagctgatg ctgggccgca tgcgctgcct
      301 cgaggccttg ggggaatggg gtcaactcca ccagcagtgc tgtgaaaagt ggaccctggt
      361 taatgatgag acccaagcca agatggcccg gatggctgct gcagctgcat ggggtttagg
      421 tcagtgggac agcatggaag aatacacctg tatgatccct cgggacaccc atgatggggc
      481 attttataga gctgtgctgg cactgcatca ggacctcttc tccttggcac aacagtgcat
      541 tgacaaggcc agggacctgc tggatgctga attaactgca atggcaggag agagttacag
      601 tcgggcatat ggggccatgg tttcttgcca catgctgtcc gagctggagg aggttatcca
      661 gtacaaactt gtccccgagc gacgagagat catccgccag atctggtggg agagactgca
      721 gggctgccag cgtatcgtag aggactggca gaaaatcctt atggtgcggt cccttgtggt
      781 cagccctcat gaagacatga gaacctggct caagtatgca agcctgtgcg gcaagagtgg
      841 caggctggct cttgctcata aaactttagt gttgctcctg ggagttgatc cgtctcggca
      901 acttgaccat cctctgccaa cagttcaccc tcaggtgacc tatgcctaca tgaaaaacat
      961 gtggaagagt gcccgcaaga tcgatgcctt ccagcacatg cagcattttg tccagaccat
     1021 gcagcaacag gcccagcatg ccatcgctac tgaggaccag cagcataagc aggaactgca
     1081 caagctcatg g
//
