LOCUS       sequence-133093-         995 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  activating MTOR mutation.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Grabiner BC, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, Jordan
            A, Beck AH, Sabatini DM
  TITLE     A diverse array of cancer-associated MTOR mutations are 
            hyperactivating and can predict rapamycin sensitivity.
  JOURNAL   Cancer Discov. 2014 May;4(5):554-63. doi: 
            10.1158/2159-8290.CD-13-0929. Epub 2014 Mar 14.
  PUBMED    24631838
REFERENCE   2  (bases 1 to 995)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/2159-8290.CD-13-0929"; journalName: "Cancer Discov"; date: 
            "2014-05"; volume: "4"; issue: "5"; pages: "554-63"
COMMENT     Sequence Label: pcDNA3-FLAG-MTOR-E1799K
FEATURES             Location/Qualifiers
     source          1..995
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 gagcacgacc gcagctggta caaggcctgg catgcgtggg cagtgatgaa cttcaaagct
       61 gtgctacact acaaacatca gaaccaagcc cgcgatgaga agaagaaact gcgtcatgcc
      121 agcggggcca acatcaccaa cgccaccact gccgccacca cggccgccac tgccaccacc
      181 actgccagca ccgagggcag caacagtgag agcgaggccg agagcaccga gaacagcccc
      241 accccatcgc cgctgcagaa gaaggtcact gaggatctgt ccaaaaccct cctgatgtac
      301 acggtgcctg ccgtccaggg cttcttccgt tccatctcct tgtcacgagg caacaacctc
      361 caggatacac tcagagttct caccttatgg tttgattatg gtcactggcc agatgtcaat
      421 gaggccttag tggagggggt gaaagccatc cagattgata cctggctaca ggttatacct
      481 cagctcattg caagaattga tacgcccaga cccttggtgg gacgtctcat tcaccagctt
      541 ctcacagaca ttggtcggta ccacccccag gccctcatct acccactgac agtggcttct
      601 aagtctacca cgacagcccg gcacaatgca gccaacaaga ttctgaagaa catgtgtgag
      661 cacagcaaca ccctggtcca gcaggccatg atggtgagcg aggagctgat ccgagtggcc
      721 atcctctggc atgagatgtg gcatgaaggc ctggaagagg catctcgttt gtactttggg
      781 gaaaggaacg tgaaaggcat gtttgaggtg ctggagccct tgcatgctat gatggaacgg
      841 ggcccccaga ctctgaagga aacatccttt aatcaggcct atggtcgaga tttaatggag
      901 gcccaagagt ggtgcaggaa gtacatgaaa tcagggaatg tcaaggacct cacccaagcc
      961 tgggacctct attatcatgt gttccgacga atctc
//
