LOCUS       sequence-141092-         716 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Progerin mutant where Serine 22 is mutated to aspartic acid and 
            where there is a substitution of cysteine in CaaX-motif by a serine.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 716)
  AUTHORS   Moiseeva O, Lopes-Paciencia S, Huot G, Lessard F, Ferbeyre G
  TITLE     Permanent farnesylation of lamin A mutants linked to progeria 
            impairs its phosphorylation at serine 22 during interphase.
  JOURNAL   Aging (Albany NY). 2016 Feb;8(2):366-81.
  PUBMED    26922519
REFERENCE   2  (bases 1 to 716)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Aging 
            (Albany NY)."; date: "2016-02"; volume: "8(2)"; pages: "366-81"
COMMENT     Sequence Label: Progerin-S22D-CS-pLPC
FEATURES             Location/Qualifiers
     source          1..716
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 gcagcggggc gcaggccagc tccactccgc tggaccccac ccgcatcacc cggctgcagg
       61 agaaggagga cctgcaggag ctcaatgatc gcttggcggt ctacatcgac cgtgtgcgct
      121 cgctggaaac ggagaacgca gggctgcgcc ttcgcatcac cgagtctgaa gaggtggtca
      181 gccgcgaggt gtccggcatc aaggccgcct acgaggccga gctcggggat gcccgcaaga
      241 cccttgactc agtagccaag gagcgcgccc gcctgcagct ggagctgagc aaagtgcgtg
      301 aggagtttaa ggagctgaaa gcgcgcaata ccaagaagga gggtgacctg atagctgctc
      361 aggctcggct gaaggacctg gaggctctgc tgaactccaa ggaggccgca ctgagcactg
      421 ctctcagtga gaagcgcacg ctggagggcg agctgcatga tctgcggggc caggtggcca
      481 agcttgaggc agccctaggt gaggccaaga agcaacttca ggatgagatg ctgcggcggg
      541 tggatgctga gaacaggctg cagaccatga aggaggaact ggacttccag aagaacatct
      601 acagtgagga gctgcgtgag accaagcgcc gtcatgagac ccgactggtg gagattgaca
      661 atgggaagca gcgtgagttt gagagccggc tggcggatgc gctgcaggaa ctgcgg
//
