LOCUS       sequence-141161-         856 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Progerin mutant where Serine 22 is mutated to aspartic acid and 
            where there is a substitution of cysteine in CaaX-motif by a serine.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 856)
  AUTHORS   Moiseeva O, Lopes-Paciencia S, Huot G, Lessard F, Ferbeyre G
  TITLE     Permanent farnesylation of lamin A mutants linked to progeria 
            impairs its phosphorylation at serine 22 during interphase.
  JOURNAL   Aging (Albany NY). 2016 Feb;8(2):366-81.
  PUBMED    26922519
REFERENCE   2  (bases 1 to 856)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Aging 
            (Albany NY)."; date: "2016-02"; volume: "8(2)"; pages: "366-81"
COMMENT     Sequence Label: Progerin-S22D-CS-pLPC
FEATURES             Location/Qualifiers
     source          1..856
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 aatcttttat tttatcggcc ctctagatgc atgctcgagt tacatgatgc tgctgttctg
       61 ggggctctgg gctcctgagc cgctggcaga tgccttgtcg gcaggctgcc cgcaggtccc
      121 gcacagcacg gtgcgcgagc gcaggttgta ctcagcgggg tcccccgagc tgctgcagtg
      181 ggagccgtgg tggtgatgga gcaggtcatc tccatcctca tcctcgtcgt cctcaaccac
      241 agtcactgag cgcaccagct tgcgcatggc cacttcttcc ccagtggagt tgatgagagc
      301 cgtacgcagg ctgttcccgc agccccaggt gttctgtgcc ttccacacca ggtcggtagg
      361 ggggctgtgg gtggccccag ctcctgcagc ccagatcgtc accacctgcc cagccttcag
      421 ggtgaacttt ggtgggaacc ggtaagtcag caagggatca tctccattct ggcgcttgat
      481 ctgccaattg cccatggact ggtcctcatt ggacttgttg cgcagccgga caaacttgcc
      541 ctcctcatcc acctcctcca cggccacgcg cccgctagtg cgtgcgtgct gtgagaagct
      601 gctgcggctc tcagtggact ccagtttgcg ctttttggtg acgctgcccc caccctgtgt
      661 ctgggatgag tgagaggaag cacggccacg gctgcgctgc gaggtagggc tgggggacag
      721 gcgtagcctc tcctcctcgc cctccaagag cttgcggtag gcgtggatct ccatgtccag
      781 ggccagcttg atgtccagaa gctcctggta ctcgtccagc tgctgctgca tccttgcccg
      841 catctcggcc atctcc
//
