LOCUS       sequence-142711-         994 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Study the role of aberrant expression of TKTL1 in HNSCC 
            tumorigenesis.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Sun W, Liu Y, Glazer CA, Shao C, Bhan S, Demokan S, Zhao M, Rudek 
            MA, Ha PK, Califano JA
  TITLE     TKTL1 is activated by promoter hypomethylation and contributes to 
            head and neck squamous cell carcinoma carcinogenesis through 
            increased aerobic glycolysis and HIF1alpha stabilization.
  JOURNAL   Clin Cancer Res. 2010 Feb 1;16(3):857-66. doi: 
            10.1158/1078-0432.CCR-09-2604. Epub 2010 Jan 26.
  PUBMED    20103683
REFERENCE   2  (bases 1 to 994)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/1078-0432.CCR-09-2604"; journalName: "Clin Cancer Res"; 
            date: "2010-02-1- 1"; volume: "16"; issue: "3"; pages: "857-66"
COMMENT     Sequence Label: TKTL1
FEATURES             Location/Qualifiers
     source          1..994
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     47..66
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        47..65
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
ORIGIN
        1 ctctctggct aactagagaa cccactgctt actggcttat cgaaattaat acgactcact
       61 atagggagac ccaagcttat ggcggatgct gaggcgaggg ctgagttccc ggaggaggcc
      121 agacctgaca ggggcacctt gcaggtgttt caagatatgg ccagccgctt gcgaatccat
      181 tccatcaggg ccacatgctc cacgagctcc ggccacccta catcatgtag cagttcttct
      241 gagatcatgt ctgtgctgtt cttctacatc atgaggtaca agcagtcaga tccagagaat
      301 ccggacaacg accgatttgt cctcgcaaag agactgtcgt ttgtggatgt ggcaacagga
      361 tggctcggac aaggactggg agttgcatgt ggaatggcat atactggcaa gtacttcgac
      421 agggccagct accgggtgtt ctgcctcatg agtgatggcg agtcctcaga aggctctgtc
      481 tgggaggcaa tggcctttgc ttcctactac agtctggaca atcttgtggc aacctttgat
      541 gtgaaccgcc tgggacacag tggtgcattg cccgccgagc actgcataaa catctatcag
      601 aggcgctgcg aagcctttgg gtggaacact tatgtggtgg acggccggga cgtggaggca
      661 ctgtgccagg tattctggca ggcttctcag gtgaagcaca agcccactgc tgtggtggcc
      721 aagaccttca agggccgggg caccccaagt attgaggatg cagaaagttg gcatgcaaag
      781 ccaatgccga gagaaagagc agatgccatt atcaaattaa ttgagagcca gatacagacc
      841 agcaggaatc ttgacccaca gccccccatt gaggactcac ctgaagtcaa catcacagat
      901 gtaaggatga cctctccacc tgattacaga gttggtgaca agatagctac tcggaaagca
      961 tgcggtctgg ctctggctaa gctgggccta cccg
//
