LOCUS       sequence-142712-         938 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Study the role of aberrant expression of TKTL1 in HNSCC 
            tumorigenesis.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 938)
  AUTHORS   Sun W, Liu Y, Glazer CA, Shao C, Bhan S, Demokan S, Zhao M, Rudek 
            MA, Ha PK, Califano JA
  TITLE     TKTL1 is activated by promoter hypomethylation and contributes to 
            head and neck squamous cell carcinoma carcinogenesis through 
            increased aerobic glycolysis and HIF1alpha stabilization.
  JOURNAL   Clin Cancer Res. 2010 Feb 1;16(3):857-66. doi: 
            10.1158/1078-0432.CCR-09-2604. Epub 2010 Jan 26.
  PUBMED    20103683
REFERENCE   2  (bases 1 to 938)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/1078-0432.CCR-09-2604"; journalName: "Clin Cancer Res"; 
            date: "2010-02-1- 1"; volume: "16"; issue: "3"; pages: "857-66"
COMMENT     Sequence Label: TKTL1
FEATURES             Location/Qualifiers
     source          1..938
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 tatagaatag ggccctctag attagttcag caacatgcat ttcacggcca ctatgatatg
       61 tctggcacta attccataca tatccagcaa ttcctcggac ttcccactct ggggcactcc
      121 cgacactgcc agcgaatgaa cctgaatgtc aggatccatg gagacggctg cgcagacagc
      181 ttccccgatg ccaccttgcg ggtagtgatc ctccactgta atgatccggc cctctgtggc
      241 ttttgcactg gagacgatgg tggcgacatc cagaggttta atggtaaaca ggtcgatgac
      301 acggataaaa atatcttgtt tcgaaagctc atcagcagct gctaaggctt catacacagt
      361 aattccagct ccaataactg tgaccttgtc actgacacag tggcggagga ccttggcctg
      421 tccgatctca aagcgttctt gtggggtgta aataaccata gtttctggtc gggtggtccg
      481 aatgaagcac atccccttgg cattggctgc cagagcaaca gcatgctccg tggagacggc
      541 atcagttggg tagaagatcg tgcacttggg aatggttcgg aacatggcta tatcctccag
      601 ggccatctgg gaagcaccat cgtcaccaac agatacccca cagtgggaac caataatgtt
      661 gatgttgctc tcagcgaggc ctcctatccg gatgtgatca aatgctcgag tcagaaaggc
      721 agcaaaggtg ctagcaaaag caatggtccg tccacgggag gcacagccca gagccacgct
      781 caccatgttt tgttcagcca taaagcactc gatgaagcgc tcagggtact ccttgttgaa
      841 tatctcagag aaagtagagt acctggtgtc accatccagc acaacgactc tgttgttcgc
      901 gtagcccagc ttagccagag ccagaccgca tgctttcc
//
