LOCUS       sequence-14326-e        1636 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Yamagishi M, Okamoto H
  TITLE     Competition for ligands between FGFR1 and FGFR4 regulates Xenopus 
            neural development.
  JOURNAL   Int J Dev Biol. 2010  . 54(1):93-104.
  PUBMED    20013652
REFERENCE   2  (bases 1 to 1636)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Int J Dev 
            Biol. 2010  . 54(1):93-104."
COMMENT     Sequence Label: iXFGFR4r
FEATURES             Location/Qualifiers
     source          1..1636
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      11..20
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     CDS             17..58
                     /codon_start=1
                     /product="N-myristoylation signal from Src kinase (Pellman 
                     et al., 1985; Kaplan et al., 1988)"
                     /label=myr
                     /translation="MGSSKSKPKDPSQR"
     CDS             1316..1594
                     /codon_start=1
                     /product="T2098L mutant of FKBP-rapamycin binding domain of
                     human FRAP"
                     /label=FRB*
                     /note="binds synthetic ligands such as AP21967"
                     /translation="ILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTL
                     KETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLLQAWDLYYHVFRRISK"
     CDS             1601..1627
                     /codon_start=1
                     /product="HA (human influenza hemagglutinin) epitope tag"
                     /label=HA
                     /translation="YPYDVPDYA"
ORIGIN
        1 atcgattgcc gccaccatgg ggagtagcaa gagcaagcct aaggacccca gccagcgcgt
       61 cgagatgcag acaccgcaca gcaagcagac tctgcaacca ccagctgttc ataaactggc
      121 caagttcccc ctcatacggc agttctcttt ggagtccagc tcatctggga agtccagtgc
      181 tccactgatt cgcataactc gtctctcctc aagctgtgcc cccatgctgc ctggtgtcat
      241 ggaggttgag ttaccactgg acgctaaatg ggagttccct agagacaggc ttgttctggg
      301 aaagccgctt ggagagggct gctttggcca agtggtaaga gcagagggat atggaattga
      361 gaaagaccgg cctgagaaac cagttaccgt tgcagttaag atgctcaaag ataatggcac
      421 tgacaaggac ttatcagatc tgatctctga aatggagttg atgaaggtca ttggaaaaca
      481 caaaaatata ataaacttgc tcggcgtcag cactcaagag gggccattat ttgttatagt
      541 tgaatatgct tctaagggga atctgcgtga gtttctacgt gccaggcgcc ctcccacacc
      601 ggaagatgcc tttgatatca ccaaggttcc agatgaactt ttgtccttta aggacctagt
      661 gtcttgtgct tatcaggttg cccgtggcat ggagtacctt gaatctaaga ggtgcataca
      721 ccgggatctg gcagccagaa atgttcttgt ggcagaagat aatgtcatga agattgcaga
      781 ttttggcttg gcacgagggg ttcacgatat tgactattac aagaaaacta gtaatggtcg
      841 actgcctgtt aaatggatgg ctccagaagc tttatttgac agagtttaca cccaccaaag
      901 tgacatttgg tcatttggag tgttgacatg ggagatcttt actcttggag ggtctccata
      961 tcctggaatt ccagtagaag aactatttaa actcttacgg gaaggacatc gaatggacaa
     1021 accatccaac tgtactcatg aattgtacat gttgatgagg gagtgctggc atgcagttcc
     1081 atctcagaga ccaacattta aacagctggt tgaacaactg gataggatcc tcacagctgt
     1141 ttctgaagag tatctggact tatctatgcc atttgaacag tattctccct cctgtgaaga
     1201 ttcttcaagc acatgctctt catccgatga ctctgttttt gcccacgatc cagtgccatc
     1261 ctctccctgt gtctttaatt accacaatgt tcacactcac cttgggactc tcgacatcct
     1321 ctggcatgag atgtggcatg aaggcctgga agaggcatct cgtttgtact ttggggaaag
     1381 gaacgtgaaa ggcatgtttg aggtgctgga gcccttgcat gctatgatgg aacggggccc
     1441 ccagactctg aaggaaacat cctttaatca ggcctatggt cgagatttaa tggaggccca
     1501 agagtggtgc aggaagtaca tgaaatcagg gaatgtcaag gacctcctcc aagcctggga
     1561 cctctattat catgtgttcc gacgaatctc aaagactagt tatccgtacg acgtaccaga
     1621 ctacgcataa gaattc
//
