LOCUS       sequence-145650-         487 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  vector encoding both shRNA against CDK4(2) and shRNA against 
            CDK6(2).
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Acevedo M, Vernier M, Mignacca L, Lessard F, Huot G, Moiseeva O, 
            Bourdeau V, Ferbeyre G
  TITLE     A CDK4/6-Dependent Epigenetic Mechanism Protects Cancer Cells from 
            PML-induced Senescence.
  JOURNAL   Cancer Res. 2016 Jun 1;76(11):3252-64. doi: 
            10.1158/0008-5472.CAN-15-2347. Epub 2016 Mar 29.
  PUBMED    27206849
REFERENCE   2  (bases 1 to 487)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/0008-5472.CAN-15-2347"; journalName: "Cancer Res"; date: 
            "2016-06-1- 1"; volume: "76"; issue: "11"; pages: "3252-64"
COMMENT     Sequence Label: shCDK4/6(2)
FEATURES             Location/Qualifiers
     source          1..487
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     ncRNA           147..161
                     /label=miR-30a loop
                     /note="loop from the the 71-nt precursor of the human 
                     miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
     ncRNA           189..315
                     /label=3' miR-30a
                     /note="sequence downstream of the 71-nt precursor of the 
                     human miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
     ncRNA           352..473
                     /label=5' miR-30a
                     /note="sequence upstream of the 71-nt precursor of the 
                     human miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
ORIGIN
        1 aatgaggctt cagtacttta cagaatcgtt gcctgcacat cttggaaaca cttgctggga
       61 ttacttcttc aggttaaccc aacagaaggc tcgagaaggt atattgctgt tgacagtgag
      121 cgagcactta cacccgtggt tgtttagtga agccacagat gtaaacaacc acgggtgtaa
      181 gtgcctgcct actgcctcgg aattcaaggg gctactttag gagcaattat cttgtttact
      241 aaaactgaat accttgctat ctctttgata catttttaca aagctgaatt aaaatggtat
      301 aaattaaatc acttttttgg atctctcgac tagggataac agggtaattg tttgaatgag
      361 gcttcagtac tttacagaat cgttgcctgc acatcttgga aacacttgct gggattactt
      421 cttcaggtta acccaacaga aggctcgaga aggtatattg ctgttgacag tgagcgtccg
      481 agtagtg
//
