LOCUS       sequence-145930-         872 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Overexpression of FLT3 Y591F/Y919F mutant in mammalian cells.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 872)
  AUTHORS   Kazi JU, Sun J, Phung B, Zadjali F, Flores-Morales A, Ronnstrand L
  TITLE     Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3
            signal transduction through direct binding to phosphorylated 
            tyrosines 591 and 919 of Flt3.
  JOURNAL   J Biol Chem. 2012 Oct 19;287(43):36509-17. doi: 
            10.1074/jbc.M112.376111. Epub 2012 Sep 5.
  PUBMED    22952242
REFERENCE   2  (bases 1 to 872)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1074/jbc.M112.376111"; journalName: "J Biol Chem"; date: 
            "2012-10-19- 19"; volume: "287"; issue: "43"; pages: "36509-17"
COMMENT     Sequence Label: pcDNA3-Flt3-Y591F/Y919F
FEATURES             Location/Qualifiers
     source          1..872
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     28..47
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        28..46
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
ORIGIN
        1 acccactgct tactggctta tcgaaattaa tacgactcac tatagggaga cccaagcttg
       61 gtaccgagct cggatccatg ccggcgttgg cgcgcgacgg cggccagctg ccgctgctcg
      121 ttgttttttc tgcaatgata tttgggacta ttacaaatca agatctgcct gtgatcaagt
      181 gtgttttaat caatcataag aacaatgatt catcagtggg gaagtcatca tcatatccca
      241 tggtatcaga atccccggaa gacctcgggt gtgcgttgag accccagagc tcagggacag
      301 tgtacgaagc tgccgctgtg gaagtggatg tatctgcttc catcacactg caagtgctgg
      361 tcgatgcccc agggaacatt tcctgtctct gggtctttaa gcacagctcc ctgaattgcc
      421 agccacattt tgatttacaa aacagaggag ttgtttccat ggtcattttg aaaatgacag
      481 aaacccaagc tggagaatac ctacttttta ttcagagtga agctaccaat tacacaatat
      541 tgtttacagt gagtataaga aataccctgc tttacacatt aagaagacct tactttagaa
      601 aaatggaaaa ccaggacgcc ctggtctgca tatctgagag cgttccagag ccgatcgtgg
      661 aatgggtgct ttgcgattca cagggggaaa gctgtaaaga agaaagtcca gctgttgtta
      721 aaaaggagga aaaagtgctt catgaattat ttgggatgga cataaggtgc tgtgccagaa
      781 atgaactggg cagggaatgc accaggctgt tcacaataga tctaaatcaa actcctcaga
      841 ccacattgcc acaattattt cttaaagtag gg
//
