LOCUS       sequence-147076-         395 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  vector encoding both shRNA against CDK4(1) and shRNA against 
            CDK6(1).
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Acevedo M, Vernier M, Mignacca L, Lessard F, Huot G, Moiseeva O, 
            Bourdeau V, Ferbeyre G
  TITLE     A CDK4/6-Dependent Epigenetic Mechanism Protects Cancer Cells from 
            PML-induced Senescence.
  JOURNAL   Cancer Res. 2016 Jun 1;76(11):3252-64. doi: 
            10.1158/0008-5472.CAN-15-2347. Epub 2016 Mar 29.
  PUBMED    27206849
REFERENCE   2  (bases 1 to 395)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/0008-5472.CAN-15-2347"; journalName: "Cancer Res"; date: 
            "2016-06-1- 1"; volume: "76"; issue: "11"; pages: "3252-64"
COMMENT     Sequence Label: shCDK4/6(1)
FEATURES             Location/Qualifiers
     source          1..395
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     ncRNA           complement(10..136)
                     /label=3' miR-30a
                     /note="sequence downstream of the 71-nt precursor of the 
                     human miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
     ncRNA           complement(164..178)
                     /label=miR-30a loop
                     /note="loop from the the 71-nt precursor of the human 
                     miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
     ncRNA           complement(206..327)
                     /label=5' miR-30a
                     /note="sequence upstream of the 71-nt precursor of the 
                     human miR-30a microRNA (Zeng et al., 2002)"
                     /ncRNA_class="miRNA"
ORIGIN
        1 gaattgaaaa aagtgattta atttatacca ttttaattca gctttgtaaa aatgtatcaa
       61 agagatagca aggtattcag ttttagtaaa caagataatt gctcctaaag tagccccttg
      121 aattccgagg cagtaggcat ctgagaatgg ctacctctcg atacatctgt ggcttcacta
      181 tcgagaggta gccattctca ggcgctcact gtcaacagca atataccttc tcgagccttc
      241 tgttgggtta acctgaagaa gtaatcccag caagtgtttc caagatgtgc aggcaacgat
      301 tctgtaaagt actgaagcct cattcaaaca attaccctgt tatccctagt cgagagatcc
      361 aaaaaagtga tttaatttat accattttaa ttcac
//
