LOCUS       sequence-158940-        1005 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses a codon-optimized ORF of human SF3B1 ( K700E mutant).
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Kesarwani AK, Ramirez O, Gupta AK, Yang X, Murthy T, Minella AC, 
            Pillai MM
  TITLE     Cancer-associated SF3B1 mutants recognize otherwise inaccessible 
            cryptic 3' splice sites within RNA secondary structures.
  JOURNAL   Oncogene. 2016 Aug 15. doi: 10.1038/onc.2016.279.
  PUBMED    27524419
REFERENCE   2  (bases 1 to 1005)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Oncogene. 
            2016 Aug 15. doi: 10.1038/onc.2016.279."
COMMENT     Sequence Label: pCDNA3.1-FLAG-hSF3B1-K700E
FEATURES             Location/Qualifiers
     source          1..1005
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 tttaaacggg ccctctagac tcgagcggcc gccactgtgc tggatatctg cagaattctc
       61 acaggatgta gtccagttcg tatcggatgt aagtattttt gtcgtcattg tagattctgg
      121 ggtaatgggc aatcagtgcg tcctgtgagc cgatgtagat actgttgtag attttccagt
      181 agacatcccg cacttttcgg gctgggtgaa acaggccctg gagacaatac tggagcatcc
      241 tgcaaggtcc aatggccact ctcaggccct ccagtgctcc catgacagcc tggatcacat
      301 gaggagaggt ttcaaagacg ttgggccaca cgtaattcag caggtggttc agggagtcct
      361 cgcatccgaa cccatacacg cccaggctca tatgctggac cacagctgag gcagtctgtc
      421 ggtgcaccag gtcgcgatcc atcagggcgt cctccagcag aggtgtcact gcgtagatgt
      481 aatctttccc catttcgccg atgtactcaa acaggaagct cagtgacttc aggaccccat
      541 tctgcacgtt cagttcgggc accctatact cattcatcag agcaggcagg actgtgaagg
      601 gggaacaggt ctcggccacg atggcgatgg cgactgtggt gcacacgcgg ttctgcctct
      661 cctggacttt cagattgttc agcagggtgg ccagcacgtc atgtggtcca atggcctttg
      721 cgatgtaccc aaaagtattc actgtggccc ttctaattgc tttcttgtga gccttcagca
      781 gttccagcag ctcgaaacag atgcgcatcc actcccgggc gctcacgtac tctgctcctc
      841 tgtctgcaat ccggccgacc agatcgatgc aattttcctg caccttctca tggcggtttt
      901 tcagaatggg ggtcagcctt ggcagcaggt ccttgatggg tggagtcatt ttgtgcatcc
      961 caatgacgtt cacgatagcc ttcagggccc ccaggatgga gccca
//
