LOCUS       sequence-158981-         848 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Plasmid for constitutive or doxy-inducible expression of mutant 
            human Ku70 unable to bind DNA and resistant to siRNA. Confers 
            resistance to puro. Use T-REx cells for doxycycline-inducible 
            expression..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Lamaa A, Le Bras M, Skuli N, Britton S, Frit P, Calsou P, Prats H, 
            Cammas A, Millevoi S
  TITLE     A novel cytoprotective function for the DNA repair protein Ku in 
            regulating p53 mRNA translation and function.
  JOURNAL   EMBO Rep. 2016 Apr;17(4):508-18. doi: 10.15252/embr.201541181. Epub 
            2016 Mar 10.
  PUBMED    26964895
REFERENCE   2  (bases 1 to 848)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.15252/embr.201541181"; journalName: "EMBO Rep"; date: "2016-04";
            volume: "17"; issue: "4"; pages: "508-18"
COMMENT     Sequence Label: pICE-HA-Ku70-siR-Mut6E
FEATURES             Location/Qualifiers
     source          1..848
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 gagacaagga agcgagcact cagcaggtta aagctgaagc tcaacaaaga tatagtgatc
       61 tctgtgggca tttataatct ggtccagaag gctctcgaac ctcctccaat agagctctat
      121 cgggaaacaa atgaaccagt gaaaaccaag gagcggacct ttaatacaag tacaggcggt
      181 ttgcttctgc ctagcgatac caagaggtct cagatctatg ggagtcgtca gattatactg
      241 gaggaagagg aaacagaaga gctagaacgg tttgatgatc caggtttgat gctcatgggt
      301 ttcaagccgt tggtactgct gaagaaacac cattacctga ggccctccct gttcgtgtac
      361 ccagaggagt cgctggtgat tgggagctca accctgttca gtgctctgct catcaagtgt
      421 ctggagaagg aggttgcagc attgtgcaga tacacacccg agaggaacat ccctccttat
      481 tttgtggctt tggtgccaca ggaagaagag ttggatgacc agaaaattca ggtgactcct
      541 ccaggcttcc agctggtctt tttacccttt gctgatgata aaaggaagat gccctttact
      601 gaaaaaatca tggcaactcc agagcaggtg ggcaagatga aggctatcgt tgagaagctt
      661 cgcttcacat acagaagtga cagctttgag aaccccgtgc tgcagcagca cttcaggaac
      721 ctggaggcct tggccttgga tttgatggag ccggaacaag cagtggacct gacattgccc
      781 aaggttgaag caatgaataa aagactgggc tccttggtgg atgagtttaa ggagcttgtt
      841 tacccacc
//
