LOCUS       sequence-163755-         787 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  lentiviral expression of human POLQ K121M mutant (a mutation in the 
            conserved ATP-binding site of the Walker A motif in the 
            helicase-like domain).
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Yousefzadeh MJ, Wyatt DW, Takata K, Mu Y, Hensley SC, Tomida J, 
            Bylund GO, Doublie S, Johansson E, Ramsden DA, McBride KM, Wood RD
  TITLE     Mechanism of suppression of chromosomal instability by DNA 
            polymerase POLQ.
  JOURNAL   PLoS Genet. 2014 Oct 2;10(10):e1004654. doi: 
            10.1371/journal.pgen.1004654. eCollection 2014 Oct.
  PUBMED    25275444
REFERENCE   2  (bases 1 to 787)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "PLoS 
            Genet."; date: "2014-10-2"; volume: "10(10):e1004654. doi"; pages: "
            10.1371/journal.pgen.1004654. eCollection 2014 Oct"
COMMENT     Sequence Label: pCDH-EF1-FHC-POLQ-K121M
FEATURES             Location/Qualifiers
     source          1..787
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     LTR             9..277
                     /label=5' LTR (truncated)
                     /note="truncated 5' long terminal repeat (LTR) from human 
                     T-cell leukemia virus (HTLV) type 1"
ORIGIN
        1 agcttcgagg ggctcgcatc tctccttcac gcgcccgccg ccctacctga ggccgccatc
       61 cacgccggtt gagtcgcgtt cttgcgcctc ccgcctgtgg tgcctcctga actgcgtccg
      121 ccgtctaggt aagtttaaag ctcaggtcga gaccgggcct ttgtccggcg ctcccttgga
      181 gcctacctag actcagccgg ctctccacgc tttgcctgac cctgcttgct caactctacg
      241 tctttgtttc gttttctgtt ctgcgccgtt acagatccaa gctgtgaccg gcgcctactc
      301 tagagctagc gaattcgaat ttaaatcgga tcctagcacc atgaatcttc tgcgtcggag
      361 tgggaaacgg cggcgttcag aatcaggctc agattcgttc tcgggaagcg gcggtgacag
      421 cagtgccagc ccccagttcc tctccgggtc cgtgctgagc ccgccgcccg gccttggtcg
      481 ctgcctgaag gccgcagctg caggagaatg caagcctaca gttcctgact acgaaataga
      541 caagctacta ttggcaaact ggggacttcc taaagcagtt ctggaaaaat accacagttt
      601 tggtgtaaaa aagatgtttg aatggcaggc agagtgcctt ttgcttggac aagtcctgga
      661 aggaaagaat ttagtttatt cagctcctac aagtgctggg atgactcttg tggcagaatt
      721 acttattttg aagcgggttt tggaaatgcg gaagaaagct ttgtttattc ttccctttgt
      781 ttctgtg
//
