LOCUS       sequence-165939-        1013 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  luciferase reporter for TERT promoter.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1013)
  AUTHORS   Bell RJ, Rube HT, Kreig A, Mancini A, Fouse SD, Nagarajan RP, Choi 
            S, Hong C, He D, Pekmezci M, Wiencke JK, Wrensch MR, Chang SM, Walsh
            KM, Myong S, Song JS, Costello JF
  TITLE     Cancer. The transcription factor GABP selectively binds and 
            activates the mutant TERT promoter in cancer.
  JOURNAL   Science. 2015 May 29;348(6238):1036-9. doi: 10.1126/science.aab0015.
            Epub 2015 May 14.
  PUBMED    25977370
REFERENCE   2  (bases 1 to 1013)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1126/science.aab0015"; journalName: "Science"; date: 
            "2015-05-29- 29"; volume: "348"; issue: "6238"; pages: "1036-9"
COMMENT     Sequence Label: pGL4.0-TERT WT
FEATURES             Location/Qualifiers
     source          1..1013
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      261..270
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 agaacatttc tctggcctaa ctggccggta cctgagctcg ctagcctcga gtcctgcccc
       61 ttcaccttcc agctccgcct cctccgcgcg gaccccgccc cgtcccgacc cctcccgggt
      121 ccccggccca gccccctccg ggccctccca gcccctcccc ttcctttccg cggccccgcc
      181 ctctcctcgc ggcgcgagtt tcaggcagcg ctggatctgg cctcggcggc caagcttggc
      241 aatccggtac tgttggtaaa gccaccatgg aagatgccaa aaacattaag aagggcccag
      301 cgccattcta cccactcgaa gacgggaccg ccggcgagca gctgcacaaa gccatgaagc
      361 gctacgccct ggtgcccggc accatcgcct ttaccgacgc acatatcgag gtggacatta
      421 cctacgccga gtacttcgag atgagcgttc ggctggcaga agctatgaag cgctatgggc
      481 tgaatacaaa ccatcggatc gtggtgtgca gcgagaatag cttgcagttc ttcatgcccg
      541 tgttgggtgc cctgttcatc ggtgtggctg tggccccagc taacgacatc tacaacgagc
      601 gcgagctgct gaacagcatg ggcatcagcc agcccaccgt cgtattcgtg agcaagaaag
      661 ggctgcaaaa gatcctcaac gtgcaaaaga agctaccgat catacaaaag atcatcatca
      721 tggatagcaa gaccgactac cagggcttcc aaagcatgta caccttcgtg acttcccatt
      781 tgccacccgg cttcaacgag tacgacttcg tgcccgagag cttcgaccgg gacaaaacca
      841 tcgccctgat catgaacagt agtggcagta ccggattgcc caagggcgta gccctaccgc
      901 accgcaccgc ttgtgtccga ttcagtcatg cccgcgaccc catcttcggc aaccagatca
      961 tccccgacac cgctatcctc agcgtggtgc catttcacca cggcttcggc atg
//
