LOCUS       sequence-165962-         987 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  luciferase reporter for mutant TERT promoter.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 987)
  AUTHORS   Bell RJ, Rube HT, Kreig A, Mancini A, Fouse SD, Nagarajan RP, Choi 
            S, Hong C, He D, Pekmezci M, Wiencke JK, Wrensch MR, Chang SM, Walsh
            KM, Myong S, Song JS, Costello JF
  TITLE     Cancer. The transcription factor GABP selectively binds and 
            activates the mutant TERT promoter in cancer.
  JOURNAL   Science. 2015 May 29;348(6238):1036-9. doi: 10.1126/science.aab0015.
            Epub 2015 May 14.
  PUBMED    25977370
REFERENCE   2  (bases 1 to 987)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1126/science.aab0015"; journalName: "Science"; date: 
            "2015-05-29- 29"; volume: "348"; issue: "6238"; pages: "1036-9"
COMMENT     Sequence Label: pGL4.0-TERT G228A
FEATURES             Location/Qualifiers
     source          1..987
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      266..275
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 gtgccagaac atttctctgg cctaactggc cggtacctga gctcgctagc ctcgagtcct
       61 gccccttcac cttccagctc cgcctcctcc gcgcggaccc cgccccgtcc cgacccctcc
      121 cgggtccccg gcccagcccc ttccgggccc tcccagcccc tccccttcct ttccgcggcc
      181 ccgccctctc ctcgcggcgc gagtttcagg cagcgctgga tctggcctcg gcggccaagc
      241 ttggcaatcc ggtactgttg gtaaagccac catggaagat gccaaaaaca ttaagaaggg
      301 cccagcgcca ttctacccac tcgaagacgg gaccgccggc gagcagctgc acaaagccat
      361 gaagcgctac gccctggtgc ccggcaccat cgcctttacc gacgcacata tcgaggtgga
      421 cattacctac gccgagtact tcgagatgag cgttcggctg gcagaagcta tgaagcgcta
      481 tgggctgaat acaaaccatc ggatcgtggt gtgcagcgag aatagcttgc agttcttcat
      541 gcccgtgttg ggtgccctgt tcatcggtgt ggctgtggcc ccagctaacg acatctacaa
      601 cgagcgcgag ctgctgaaca gcatgggcat cagccagccc accgtcgtat tcgtgagcaa
      661 gaaagggctg caaaagatcc tcaacgtgca aaagaagcta ccgatcatac aaaagatcat
      721 catcatggat agcaagaccg actaccaggg cttccaaagc atgtacacct tcgtgacttc
      781 ccatttgcca cccggcttca acgagtacga cttcgtgccc gagagcttcg accgggacaa
      841 aaccatcgcc ctgatcatga acagtagtgg cagtaccgga ttgcccaagg gcgtagccct
      901 accgcaccgc accgcttgtg tccgattcag tcatgcccgc gaccccatct tcggcaacca
      961 gatcatcccc gacaccgcta tcctcag
//
