LOCUS       sequence-174452-       14125 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Disturb the expression of miR167 in rice.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 14125)
  AUTHORS   Yan J, Gu Y, Jia X, Kang W, Pan S, Tang X, Chen X, Tang G
  TITLE     Effective small RNA destruction by the expression of a short tandem 
            target mimic in Arabidopsis.
  JOURNAL   Plant Cell. 2012 Feb;24(2):415-27. doi: 10.1105/tpc.111.094144. Epub
            2012 Feb 17.
  PUBMED    22345490
REFERENCE   2  (bases 1 to 14125)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1105/tpc.111.094144"; journalName: "Plant Cell"; date: 
            "2012-02"; volume: "24"; issue: "2"; pages: "415-27"
COMMENT     Sequence Label: Osa-pCAMBIA-1301-STTM167
FEATURES             Location/Qualifiers
     source          1..14125
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    191..212
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     promoter        join(227..232,233..250,251..257)
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    265..281
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     primer_bind     270..292
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     primer_bind     289..305
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     289..305
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     primer_bind     504..523
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        504..522
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
     promoter        930..1275
                     /label=CaMV 35S promoter
                     /note="strong constitutive promoter from cauliflower mosaic
                     virus"
     polyA_signal    1454..1630
                     /label=CaMV poly(A) signal
                     /note="cauliflower mosaic virus polyadenylation signal"
     promoter        complement(2192..2210)
                     /label=SP6 promoter
                     /note="promoter for bacteriophage SP6 RNA polymerase"
     primer_bind     complement(2193..2210)
                     /label=SP6
                     /note="SP6 promoter, forward primer"
     CDS             complement(2281..2940)
                     /codon_start=1
                     /gene="cat"
                     /product="chloramphenicol acetyltransferase"
                     /label=CmR
                     /note="confers resistance to chloramphenicol"
                     /translation="MEKEITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAFL
                     KTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETFSS
                     LWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNVANM
                     DNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQGGA"
     primer_bind     2855..2874
                     /label=CAT-R
                     /note="Chloramphenicol resistance gene, reverse primer"
     promoter        complement(join(2977..2982,2983..2999,3000..3005))
                     /label=tet promoter
                     /note="E. coli promoter for tetracycline efflux protein 
                     gene"
     promoter        3340..3386
                     /label=minimal CaMV 35S promoter
                     /note="minimal 35S promoter from cauliflower mosaic virus"
     CDS             join(3405..3419,3610..5427)
                     /codon_start=1
                     /product="beta-glucuronidase"
                     /label=GUS
                     /note="This version of the gusA gene has a 5' extension 
                     with a catalase intron to ensure expression in plants but 
                     not bacteria."
                     /translation="MVDLRNRRLVRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWES
                     ALQESRAIAVPGSFNDQFADADIRNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGK
                     VWVNNQEVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGK
                     KKQSYFHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSV
                     ELRDADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRS
                     VAVKGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYP
                     YAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQA
                     IKELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCD
                     AHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVDT
                     LAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGNKK
                     GIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ"
     intron          3420..3609
                     /label=cat1 intron
                     /note="castor bean catalase intron, modified"
     CDS             5434..5451
                     /codon_start=1
                     /product="6xHis affinity tag"
                     /label=6xHis
                     /translation="HHHHHH"
     terminator      5486..5738
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     misc_feature    5760..5784
                     /label=RB T-DNA repeat
                     /note="right border repeat from nopaline C58 T-DNA"
     CDS             7085..7714
                     /codon_start=1
                     /product="stability protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 StaA
                     /translation="MKVIAVLNQKGGSGKTTIATHLARALQLAGADVLLVDSDPQGSAR
                     DWAAVREDQPLTVVGIDRPTIDRDVKAIGRRDFVVIDGAPQAADLAVSAIKAADFVLIP
                     VQPSPYDIWATADLVELVKQRIEVTDGRLQAAFVVSRAIKGTRIGGEVAEALAGYELPI
                     LESRITQRVSYPGTAAAGTTVLESEPEGDAAREVQALAAEIKSKLI"
     CDS             8143..9216
                     /codon_start=1
                     /product="replication protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 RepA
                     /translation="MSGRKPSGPVQIGAALGDDLVEKLKAAQAAQRQRIEAEARPGESW
                     QAAADRIRKESRQPPAAGAPSIRKPPKGDEQPDFFVPMLYDVGTRDSRSIMDVAVFRLS
                     KRDRRAGEVIRYELPDGHVEVSAGPAGMASVWDYDLVLMAVSHLTESMNRYREGKGDKP
                     GRVFRPHVADVLKFCRRADGGKQKDDLVETCIRLNTTHVAMQRTKKAKNGRLVTVSEGE
                     ALISRYKIVKSETGRPEYIEIELADWMYREITEGKNPDVLTVHPDYFLIDPGIGRFLYR
                     LARRAAGKAEARWLFKTIYERSGSAGEFKKFCFTVRKLIGSNDLPEYDLKEEAGQAGPI
                     LVMRYRNLIEGEASAGS"
     rep_origin      9282..9476
                     /label=pVS1 oriV
                     /note="origin of replication for the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
     primer_bind     complement(9712..9734)
                     /label=pGEX 3'
                     /note="pGEX vectors, reverse primer"
     misc_feature    9820..9960
                     /label=bom
                     /note="basis of mobility region from pBR322"
     primer_bind     9875..9894
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
     primer_bind     complement(9975..9992)
                     /label=L4440
                     /note="L4440 vector, forward primer"
     rep_origin      complement(10146..10734)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     CDS             complement(10821..11615)
                     /codon_start=1
                     /gene="aphA-3"
                     /product="aminoglycoside phosphotransferase"
                     /label=KanR
                     /note="confers resistance to kanamycin"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKM
                     TDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEYED
                     EQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWEEDT
                     PFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIA
                     FCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     misc_feature    12040..12064
                     /label=LB T-DNA repeat
                     /note="left border repeat from nopaline C58 T-DNA"
     polyA_signal    12142..12316
                     /label=CaMV poly(A) signal
                     /note="cauliflower mosaic virus polyadenylation signal"
     CDS             complement(12357..13382)
                     /codon_start=1
                     /product="hygromycin B phosphotransferase"
                     /label=HygR
                     /note="confers resistance to hygromycin"
                     /translation="MKKPELTATSVEKFLIEKFDSVSDLMQLSEGEESRAFSFDVGGRG
                     YVLRVNSCADGFYKDRYVYRHFASAALPIPEVLDIGEFSESLTYCISRRSQGVTLQDLP
                     ETELPAVLQPVAEAMDAIAAADLSQTSGFGPFGPQGIGQYTTWRDFICAIADPHVYHWQ
                     TVMDDTVSASVAQALDELMLWAEDCPEVRHLVHADFGSNNVLTDNGRITAVIDWSEAMF
                     GDSQYEVANIFFWRPWLACMEQQTRYFERRHPELAGSPRLRAYMLRIGLDQLYQSLVDG
                     NFDDAAWAQGRCDAIVRSGAGTVGRTQIARRSAAVWTDGCVEVLADSGNRRPSTRPRAK
                     K"
     promoter        complement(13449..14125)
                     /label=CaMV 35S promoter (enhanced)
                     /note="cauliflower mosaic virus 35S promoter with a 
                     duplicated enhancer region"
ORIGIN
        1 atagcccttt ggtcttctga gactgtatct ttgatattct tggagtagac gagagtgtcg
       61 tgctccacca tgttggcaag ctgctctagc caatacgcaa accgcctctc cccgcgcgtt
      121 ggccgattca ttaatgcagc tggcacgaca ggtttcccga ctggaaagcg ggcagtgagc
      181 gcaacgcaat taatgtgagt tagctcactc attaggcacc ccaggcttta cactttatgc
      241 ttccggctcg tatgttgtgt ggaattgtga gcggataaca atttcacaca ggaaacagct
      301 atgacatgat tacgaattcg agctcggtac ccggggatcc tctagctaga ttaattaagt
      361 ttgcaagcag cagattacgc gcagaaaaaa aggatctcaa ggagatcctt tggatcacaa
      421 aaaaaagccc gctcattagg cgggttaaat tcccgggtac tgcagccgat tcattaatgc
      481 aggttaacct ggcttatcga aattaatacg actcactata gggagaccgg tagatctgat
      541 ccctactcca aaaatgtcaa agatacagtc tcagaagacc aaagggctat tgagactttt
      601 caacaaaggg taatttcggg aaacctcctc ggattccatt gcccagctat ctgtcacttc
      661 atcgaaagga cagtggaaaa ggaaggtggc tcctacaaat gccatcattg cgataaagga
      721 aaggctatca ttcaagatgc ctctgccgac agtggtccca aagatggacc cccacccacg
      781 aggagcatcg tgggaaaaga agacgttcca accacgtctt caaagcaagt ggattgatgt
      841 gacatctcca ctgacgtaag ggatgacgca caatcccgcc cctactccaa aaatgtcaaa
      901 gatactgtct cagaagacca aagggctatt gagacttttc aacaaagggt aatttcggga
      961 aacctcctcg gattccattg cccagctacc tgtcacctca tcgaaaggac agtagaaaag
     1021 gaaggtggct cctacaaatg ccatcatcgc gataaaggaa aggctatcat tcaagatgcc
     1081 tctgccgaca gtggtcccaa agatggaccc ccacccacga ggagcatcgt ggaaaaagaa
     1141 gacgttccaa ccacgtcttc aaagcaagtg gattgatgtg acatctccac tgacataagg
     1201 gatgacgcac aaccccacta tccttcgcaa gacccttcct ctatataagg aagttcattt
     1261 catttggaga ggacagccca agcttggtac ctagatcatg ctctaggcag cttcagttgt
     1321 tgttgttatg gtctaattta aatatggtct aaagaagaag aatcagatca tgctctaggc
     1381 agcttcagga tccactagtg aattcggtac gctgaaatca ccagtctctc tctacaaatc
     1441 tatctctctc tattttctcc ataaataatg tgtgagtagt ttcccgataa gggaaattag
     1501 ggttcttata gggtttcgct catgtgttga gcatataaga gacccttagt atgtatttgt
     1561 atttgtaaaa tacttctatc aataaaattt ctaattccta aaaccaaaat ccagtactaa
     1621 aatccagatc tcctaaagtc cctatagatc tttgtcgtga atataaacca gacacgagac
     1681 gactagacct ggagcccaga cgccgttcga agctagaagt accgcttagg caggaggccg
     1741 ttagggaaaa gatgctaagg cagggttggt tacgttgact cccccgtagg tttggtttaa
     1801 atatgatgaa gtggacggaa ggaaggagga agacaaggaa ggataaggtt gcaggccctg
     1861 tgcaaggtaa gaagatggaa atttgataga ggtacgctac tatacttata ctatacgcta
     1921 agggaatgat tgtatttata ccctataccc cctaataacc ccttatcaat ttaagaaata
     1981 atccgcataa gcccccgctt aaaaattggt atcagagcca tgaataggtc tatgaccaaa
     2041 actcaagagg ataaaacctc accaaaatac gaaagagtcc ttaactctaa agataaaaga
     2101 tctttcaaga tcaaaactag ttccctcaca ccggtgacgg ggatcgcatg cgacctctag
     2161 accatcacat tggagcttca gctgctcgag ttctatagtg tcacctaaat cgtatgtgta
     2221 tgatacataa ggttatgtat taattgtagc cgcgttctaa cgtcgacagg cctgtaccaa
     2281 ttacgccccg ccctgccact catcgcagta ctgttgtaat tcattaagca ttctgccgac
     2341 atggaagcca tcacaaacgg catgatgaac ctgaatcgcc agcggcatca gcaccttgtc
     2401 gccttgcgta taatatttgc ccatggtgaa aacgggggcg aagaagttgt ccatattggc
     2461 cacgtttaaa tcaaaactgg tgaaactcac ccagggattg gctgagacga aaaacatatt
     2521 ctcaataaac cctttaggga aataggccag gttttcaccg taacacgcca catcttgcga
     2581 atatatgtgt agaaactgcc ggaaatcgtc gtggtattca ctccagagcg atgaaaacgt
     2641 ttcagtttgc tcatggaaaa cggtgtaaca agggtgaaca ctatcccata ttaccagctc
     2701 accgtctttc attgccatac ggaactccgg atgagcattc atcaggcggg caagaatgtg
     2761 aataaaggcc ggataaaact tgtgcttatt tttctttacg gtctttaaaa aggccgtaat
     2821 atccagctga acggtctggt tataggtaca ttgagcaact gactgaaatg cctcaaaatg
     2881 ttctttacga tgccattggg atatatcaac ggtggtatat ccagtgattt ctttctccat
     2941 tttagcttcc ttagctcctg aaaatctcga taactcatta aaacttatcg atgataagct
     3001 gtcaaacatg agaatttagc ccgcctaatg agcgggcttt ttgctgtgat ccgcgttgct
     3061 ggcgtttttc cataggctcc gcccccctga cgagcatcac aaaaatcgac gctcaagtca
     3121 gaggtggcga aacccgacag gactataaag ataccaggcg tttcccccct ggaagctccc
     3181 tcgtgcgctc tcctgttccg accctgccgc ttaccggata cctgtccgcc tttcttaatt
     3241 aactgcaggc atgcaagctt ccttttgtct cccttttgtc tcccttttgt ctcccttttg
     3301 tctccctttt gtctcccttt tgtctccctt ttgtctctcg caagaccctt cctctatata
     3361 aggaagttca tttcatttgg agagaacacg ggggactctt gaccatggta gatctgaggg
     3421 taaatttcta gtttttctcc ttcattttct tggttaggac ccttttctct ttttattttt
     3481 ttgagctttg atctttcttt aaactgatct attttttaat tgattggtta tggtgtaaat
     3541 attacatagc tttaactgat aatctgatta ctttatttcg tgtgtctatg atgatgatga
     3601 tagttacaga accgacgact cgtccgtcct gtagaaaccc caacccgtga aatcaaaaaa
     3661 ctcgacggcc tgtgggcatt cagtctggat cgcgaaaact gtggaattga tcagcgttgg
     3721 tgggaaagcg cgttacaaga aagccgggca attgctgtgc caggcagttt taacgatcag
     3781 ttcgccgatg cagatattcg taattatgcg ggcaacgtct ggtatcagcg cgaagtcttt
     3841 ataccgaaag gttgggcagg ccagcgtatc gtgctgcgtt tcgatgcggt cactcattac
     3901 ggcaaagtgt gggtcaataa tcaggaagtg atggagcatc agggcggcta tacgccattt
     3961 gaagccgatg tcacgccgta tgttattgcc gggaaaagtg tacgtatcac cgtttgtgtg
     4021 aacaacgaac tgaactggca gactatcccg ccgggaatgg tgattaccga cgaaaacggc
     4081 aagaaaaagc agtcttactt ccatgatttc tttaactatg ccggaatcca tcgcagcgta
     4141 atgctctaca ccacgccgaa cacctgggtg gacgatatca ccgtggtgac gcatgtcgcg
     4201 caagactgta accacgcgtc tgttgactgg caggtggtgg ccaatggtga tgtcagcgtt
     4261 gaactgcgtg atgcggatca acaggtggtt gcaactggac aaggcactag cgggactttg
     4321 caagtggtga atccgcacct ctggcaaccg ggtgaaggtt atctctatga actgtgcgtc
     4381 acagccaaaa gccagacaga gtgtgatatc tacccgcttc gcgtcggcat ccggtcagtg
     4441 gcagtgaagg gcgaacagtt cctgattaac cacaaaccgt tctactttac tggctttggt
     4501 cgtcatgaag atgcggactt gcgtggcaaa ggattcgata acgtgctgat ggtgcacgac
     4561 cacgcattaa tggactggat tggggccaac tcctaccgta cctcgcatta cccttacgct
     4621 gaagagatgc tcgactgggc agatgaacat ggcatcgtgg tgattgatga aactgctgct
     4681 gtcggcttta acctctcttt aggcattggt ttcgaagcgg gcaacaagcc gaaagaactg
     4741 tacagcgaag aggcagtcaa cggggaaact cagcaagcgc acttacaggc gattaaagag
     4801 ctgatagcgc gtgacaaaaa ccacccaagc gtggtgatgt ggagtattgc caacgaaccg
     4861 gatacccgtc cgcaaggtgc acgggaatat ttcgcgccac tggcggaagc aacgcgtaaa
     4921 ctcgacccga cgcgtccgat cacctgcgtc aatgtaatgt tctgcgacgc tcacaccgat
     4981 accatcagcg atctctttga tgtgctgtgc ctgaaccgtt attacggatg gtatgtccaa
     5041 agcggcgatt tggaaacggc agagaaggta ctggaaaaag aacttctggc ctggcaggag
     5101 aaactgcatc agccgattat catcaccgaa tacggcgtgg atacgttagc cgggctgcac
     5161 tcaatgtaca ccgacatgtg gagtgaagag tatcagtgtg catggctgga tatgtatcac
     5221 cgcgtctttg atcgcgtcag cgccgtcgtc ggtgaacagg tatggaattt cgccgatttt
     5281 gcgacctcgc aaggcatatt gcgcgttggc ggtaacaaga aagggatctt cactcgcgac
     5341 cgcaaaccga agtcggcggc ttttctgctg caaaaacgct ggactggcat gaacttcggt
     5401 gaaaaaccgc agcagggagg caaacaagct agccaccacc accaccacca cgtgtgaatt
     5461 acaggtgacc agctcgaatt tccccgatcg ttcaaacatt tggcaataaa gtttcttaag
     5521 attgaatcct gttgccggtc ttgcgatgat tatcatataa tttctgttga attacgttaa
     5581 gcatgtaata attaacatgt aatgcatgac gttatttatg agatgggttt ttatgattag
     5641 agtcccgcaa ttatacattt aatacgcgat agaaaacaaa atatagcgcg caaactagga
     5701 taaattatcg cgcgcggtgt catctatgtt actagatcgg gaattaaact atcagtgttt
     5761 gacaggatat attggcgggt aaacctaaga gaaaagagcg tttattagaa taatcggata
     5821 tttaaaaggg cgtgaaaagg tttatccgtt cgtccatttg tatgtgcatg ccaaccacag
     5881 ggttcccctc gggatcaaag tactttgatc caacccctcc gctgctatag tgcagtcggc
     5941 ttctgacgtt cagtgcagcc gtcttctgaa aacgacatgt cgcacaagtc ctaagttacg
     6001 cgacaggctg ccgccctgcc cttttcctgg cgttttcttg tcgcgtgttt tagtcgcata
     6061 aagtagaata cttgcgacta gaaccggaga cattacgcca tgaacaagag cgccgccgct
     6121 ggcctgctgg gctatgcccg cgtcagcacc gacgaccagg acttgaccaa ccaacgggcc
     6181 gaactgcacg cggccggctg caccaagctg ttttccgaga agatcaccgg caccaggcgc
     6241 gaccgcccgg agctggccag gatgcttgac cacctacgcc ctggcgacgt tgtgacagtg
     6301 accaggctag accgcctggc ccgcagcacc cgcgacctac tggacattgc cgagcgcatc
     6361 caggaggccg gcgcgggcct gcgtagcctg gcagagccgt gggccgacac caccacgccg
     6421 gccggccgca tggtgttgac cgtgttcgcc ggcattgccg agttcgagcg ttccctaatc
     6481 atcgaccgca cccggagcgg gcgcgaggcc gccaaggccc gaggcgtgaa gtttggcccc
     6541 cgccctaccc tcaccccggc acagatcgcg cacgcccgcg agctgatcga ccaggaaggc
     6601 cgcaccgtga aagaggcggc tgcactgctt ggcgtgcatc gctcgaccct gtaccgcgca
     6661 cttgagcgca gcgaggaagt gacgcccacc gaggccaggc ggcgcggtgc cttccgtgag
     6721 gacgcattga ccgaggccga cgccctggcg gccgccgaga atgaacgcca agaggaacaa
     6781 gcatgaaacc gcaccaggac ggccaggacg aaccgttttt cattaccgaa gagatcgagg
     6841 cggagatgat cgcggccggg tacgtgttcg agccgcccgc gcacgtctca accgtgcggc
     6901 tgcatgaaat cctggccggt ttgtctgatg ccaagctggc ggcctggccg gccagcttgg
     6961 ccgctgaaga aaccgagcgc cgccgtctaa aaaggtgatg tgtatttgag taaaacagct
     7021 tgcgtcatgc ggtcgctgcg tatatgatgc gatgagtaaa taaacaaata cgcaagggga
     7081 acgcatgaag gttatcgctg tacttaacca gaaaggcggg tcaggcaaga cgaccatcgc
     7141 aacccatcta gcccgcgccc tgcaactcgc cggggccgat gttctgttag tcgattccga
     7201 tccccagggc agtgcccgcg attgggcggc cgtgcgggaa gatcaaccgc taaccgttgt
     7261 cggcatcgac cgcccgacga ttgaccgcga cgtgaaggcc atcggccggc gcgacttcgt
     7321 agtgatcgac ggagcgcccc aggcggcgga cttggctgtg tccgcgatca aggcagccga
     7381 cttcgtgctg attccggtgc agccaagccc ttacgacata tgggccaccg ccgacctggt
     7441 ggagctggtt aagcagcgca ttgaggtcac ggatggaagg ctacaagcgg cctttgtcgt
     7501 gtcgcgggcg atcaaaggca cgcgcatcgg cggtgaggtt gccgaggcgc tggccgggta
     7561 cgagctgccc attcttgagt cccgtatcac gcagcgcgtg agctacccag gcactgccgc
     7621 cgccggcaca accgttcttg aatcagaacc cgagggcgac gctgcccgcg aggtccaggc
     7681 gctggccgct gaaattaaat caaaactcat ttgagttaat gaggtaaaga gaaaatgagc
     7741 aaaagcacaa acacgctaag tgccggccgt ccgagcgcac gcagcagcaa ggctgcaacg
     7801 ttggccagcc tggcagacac gccagccatg aagcgggtca actttcagtt gccggcggag
     7861 gatcacacca agctgaagat gtacgcggta cgccaaggca agaccattac cgagctgcta
     7921 tctgaataca tcgcgcagct accagagtaa atgagcaaat gaataaatga gtagatgaat
     7981 tttagcggct aaaggaggcg gcatggaaaa tcaagaacaa ccaggcaccg acgccgtgga
     8041 atgccccatg tgtggaggaa cgggcggttg gccaggcgta agcggctggg ttgcctgccg
     8101 gccctgcaat ggcactggaa cccccaagcc cgaggaatcg gcgtgagcgg tcgcaaacca
     8161 tccggcccgg tacaaatcgg cgcggcgctg ggtgatgacc tggtggagaa gttgaaggcc
     8221 gcgcaggccg cccagcggca acgcatcgag gcagaagcac gccccggtga atcgtggcaa
     8281 gcggccgctg atcgaatccg caaagaatcc cggcaaccgc cggcagccgg tgcgccgtcg
     8341 attaggaagc cgcccaaggg cgacgagcaa ccagattttt tcgttccgat gctctatgac
     8401 gtgggcaccc gcgatagtcg cagcatcatg gacgtggccg ttttccgtct gtcgaagcgt
     8461 gaccgacgag ctggcgaggt gatccgctac gagcttccag acgggcacgt agaggtttcc
     8521 gcagggccgg ccggcatggc cagtgtgtgg gattacgacc tggtactgat ggcggtttcc
     8581 catctaaccg aatccatgaa ccgataccgg gaagggaagg gagacaagcc cggccgcgtg
     8641 ttccgtccac acgttgcgga cgtactcaag ttctgccggc gagccgatgg cggaaagcag
     8701 aaagacgacc tggtagaaac ctgcattcgg ttaaacacca cgcacgttgc catgcagcgt
     8761 acgaagaagg ccaagaacgg ccgcctggtg acggtatccg agggtgaagc cttgattagc
     8821 cgctacaaga tcgtaaagag cgaaaccggg cggccggagt acatcgagat cgagctagct
     8881 gattggatgt accgcgagat cacagaaggc aagaacccgg acgtgctgac ggttcacccc
     8941 gattactttt tgatcgatcc cggcatcggc cgttttctct accgcctggc acgccgcgcc
     9001 gcaggcaagg cagaagccag atggttgttc aagacgatct acgaacgcag tggcagcgcc
     9061 ggagagttca agaagttctg tttcaccgtg cgcaagctga tcgggtcaaa tgacctgccg
     9121 gagtacgatt tgaaggagga ggcggggcag gctggcccga tcctagtcat gcgctaccgc
     9181 aacctgatcg agggcgaagc atccgccggt tcctaatgta cggagcagat gctagggcaa
     9241 attgccctag caggggaaaa aggtcgaaaa ggtctctttc ctgtggatag cacgtacatt
     9301 gggaacccaa agccgtacat tgggaaccgg aacccgtaca ttgggaaccc aaagccgtac
     9361 attgggaacc ggtcacacat gtaagtgact gatataaaag agaaaaaagg cgatttttcc
     9421 gcctaaaact ctttaaaact tattaaaact cttaaaaccc gcctggcctg tgcataactg
     9481 tctggccagc gcacagccga agagctgcaa aaagcgccta cccttcggtc gctgcgctcc
     9541 ctacgccccg ccgcttcgcg tcggcctatc gcggccgctg gccgctcaaa aatggctggc
     9601 ctacggccag gcaatctacc agggcgcgga caagccgcgc cgtcgccact cgaccgccgg
     9661 cgcccacatc aaggcaccct gcctcgcgcg tttcggtgat gacggtgaaa acctctgaca
     9721 catgcagctc ccggagacgg tcacagcttg tctgtaagcg gatgccggga gcagacaagc
     9781 ccgtcagggc gcgtcagcgg gtgttggcgg gtgtcggggc gcagccatga cccagtcacg
     9841 tagcgatagc ggagtgtata ctggcttaac tatgcggcat cagagcagat tgtactgaga
     9901 gtgcaccata tgcggtgtga aataccgcac agatgcgtaa ggagaaaata ccgcatcagg
     9961 cgctcttccg cttcctcgct cactgactcg ctgcgctcgg tcgttcggct gcggcgagcg
    10021 gtatcagctc actcaaaggc ggtaatacgg ttatccacag aatcagggga taacgcagga
    10081 aagaacatgt gagcaaaagg ccagcaaaag gccaggaacc gtaaaaaggc cgcgttgctg
    10141 gcgtttttcc ataggctccg cccccctgac gagcatcaca aaaatcgacg ctcaagtcag
    10201 aggtggcgaa acccgacagg actataaaga taccaggcgt ttccccctgg aagctccctc
    10261 gtgcgctctc ctgttccgac cctgccgctt accggatacc tgtccgcctt tctcccttcg
    10321 ggaagcgtgg cgctttctca tagctcacgc tgtaggtatc tcagttcggt gtaggtcgtt
    10381 cgctccaagc tgggctgtgt gcacgaaccc cccgttcagc ccgaccgctg cgccttatcc
    10441 ggtaactatc gtcttgagtc caacccggta agacacgact tatcgccact ggcagcagcc
    10501 actggtaaca ggattagcag agcgaggtat gtaggcggtg ctacagagtt cttgaagtgg
    10561 tggcctaact acggctacac tagaaggaca gtatttggta tctgcgctct gctgaagcca
    10621 gttaccttcg gaaaaagagt tggtagctct tgatccggca aacaaaccac cgctggtagc
    10681 ggtggttttt ttgtttgcaa gcagcagatt acgcgcagaa aaaaaggatc tcaagaagat
    10741 cctttgatct tttctacggg gtctgacgct cagtggaacg aaaactcacg ttaagggatt
    10801 ttggtcatgc attctaggta ctaaaacaat tcatccagta aaatataata ttttattttc
    10861 tcccaatcag gcttgatccc cagtaagtca aaaaatagct cgacatactg ttcttccccg
    10921 atatcctccc tgatcgaccg gacgcagaag gcaatgtcat accacttgtc cgccctgccg
    10981 cttctcccaa gatcaataaa gccacttact ttgccatctt tcacaaagat gttgctgtct
    11041 cccaggtcgc cgtgggaaaa gacaagttcc tcttcgggct tttccgtctt taaaaaatca
    11101 tacagctcgc gcggatcttt aaatggagtg tcttcttccc agttttcgca atccacatcg
    11161 gccagatcgt tattcagtaa gtaatccaat tcggctaagc ggctgtctaa gctattcgta
    11221 tagggacaat ccgatatgtc gatggagtga aagagcctga tgcactccgc atacagctcg
    11281 ataatctttt cagggctttg ttcatcttca tactcttccg agcaaaggac gccatcggcc
    11341 tcactcatga gcagattgct ccagccatca tgccgttcaa agtgcaggac ctttggaaca
    11401 ggcagctttc cttccagcca tagcatcatg tccttttccc gttccacatc ataggtggtc
    11461 cctttatacc ggctgtccgt catttttaaa tataggtttt cattttctcc caccagctta
    11521 tataccttag caggagacat tccttccgta tcttttacgc agcggtattt ttcgatcagt
    11581 tttttcaatt ccggtgatat tctcatttta gccatttatt atttccttcc tcttttctac
    11641 agtatttaaa gataccccaa gaagctaatt ataacaagac gaactccaat tcactgttcc
    11701 ttgcattcta aaaccttaaa taccagaaaa cagctttttc aaagttgttt tcaaagttgg
    11761 cgtataacat agtatcgacg gagccgattt tgaaaccgcg gtgatcacag gcagcaacgc
    11821 tctgtcatcg ttacaatcaa catgctaccc tccgcgagat catccgtgtt tcaaacccgg
    11881 cagcttagtt gccgttcttc cgaatagcat cggtaacatg agcaaagtct gccgccttac
    11941 aacggctctc ccgctgacgc cgtcccggac tgatgggctg cctgtatcga gtggtgattt
    12001 tgtgccgagc tgccggtcgg ggagctgttg gctggctggt ggcaggatat attgtggtgt
    12061 aaacaaattg acgcttagac aacttaataa cacattgcgg acgtttttaa tgtactgaat
    12121 taacgccgaa ttaattcggg ggatctggat tttagtactg gattttggtt ttaggaatta
    12181 gaaattttat tgatagaagt attttacaaa tacaaataca tactaagggt ttcttatatg
    12241 ctcaacacat gagcgaaacc ctataggaac cctaattccc ttatctggga actactcaca
    12301 cattattatg gagaaactcg agcttgtcga tcgacagatc ccggtcggca tctactctat
    12361 ttctttgccc tcggacgagt gctggggcgt cggtttccac tatcggcgag tacttctaca
    12421 cagccatcgg tccagacggc cgcgcttctg cgggcgattt gtgtacgccc gacagtcccg
    12481 gctccggatc ggacgattgc gtcgcatcga ccctgcgccc aagctgcatc atcgaaattg
    12541 ccgtcaacca agctctgata gagttggtca agaccaatgc ggagcatata cgcccggagt
    12601 cgtggcgatc ctgcaagctc cggatgcctc cgctcgaagt agcgcgtctg ctgctccata
    12661 caagccaacc acggcctcca gaagaagatg ttggcgacct cgtattggga atccccgaac
    12721 atcgcctcgc tccagtcaat gaccgctgtt atgcggccat tgtccgtcag gacattgttg
    12781 gagccgaaat ccgcgtgcac gaggtgccgg acttcggggc agtcctcggc ccaaagcatc
    12841 agctcatcga gagcctgcgc gacggacgca ctgacggtgt cgtccatcac agtttgccag
    12901 tgatacacat ggggatcagc aatcgcgcat atgaaatcac gccatgtagt gtattgaccg
    12961 attccttgcg gtccgaatgg gccgaacccg ctcgtctggc taagatcggc cgcagcgatc
    13021 gcatccatag cctccgcgac cggttgtaga acagcgggca gttcggtttc aggcaggtct
    13081 tgcaacgtga caccctgtga acggcgggag atgcaatagg tcaggctctc gctaaactcc
    13141 ccaatgtcaa gcacttccgg aatcgggagc gcggccgatg caaagtgccg ataaacataa
    13201 cgatctttgt agaaaccatc ggcgcagcta tttacccgca ggacatatcc acgccctcct
    13261 acatcgaagc tgaaagcacg agattcttcg ccctccgaga gctgcatcag gtcggagacg
    13321 ctgtcgaact tttcgatcag aaacttctcg acagacgtcg cggtgagttc aggctttttc
    13381 atatctcatt gccccccgga tctgcgaaag ctcgagagag atagatttgt agagagagac
    13441 tggtgatttc agcgtgtcct ctccaaatga aatgaacttc cttatataga ggaagggtct
    13501 tgcgaaggat agtgggattg tgcgtcatcc cttacgtcag tggagatatc acatcaatcc
    13561 acttgctttg aagacgtggt tggaacgtct tctttttcca cgatgctcct cgtgggtggg
    13621 ggtccatctt tgggaccact gtcggcagag gcatcttgaa cgatagcctt tcctttatcg
    13681 caatgatggc atttgtaggt gccaccttcc ttttctactg tccttttgat gaagtgacag
    13741 atagctgggc aatggaatcc gaggaggttt cccgatatta ccctttgttg aaaagtctca
    13801 atagcccttt ggtcttctga gactgtatct ttgatattct tggagtagac gagagtgtcg
    13861 tgctccacca tgttcacatc aatccacttg ctttgaagac gtggttggaa cgtcttcttt
    13921 ttccacgatg ctcctcgtgg gtgggggtcc atctttggga ccactgtcgg cagaggcatc
    13981 ttgaacgata gcctttcctt tatcgcaatg atggcatttg taggtgccac cttccttttc
    14041 tactgtcctt ttgatgaagt gacagatagc tgggcaatgg aatccgagga ggtttcccga
    14101 tattaccctt tgttgaaaag tctca
//
