LOCUS       sequence-178708-        2151 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  To determine if structural domains are important for nicotinic 
            acetylcholine receptor (nAChr) channel function via dose-response 
            curves from voltage-clamped oocytes to estimate EC50's and Hill Co.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Labarca C, Nowak MW, Zhang H, Tang L, Deshpande P, Lester HA
  TITLE     Channel gating governed symmetrically by conserved leucine residues 
            in the M2 domain of nicotinic receptors.
  JOURNAL   Nature. 1995 Aug 10. 376(6540):514-6.
  PUBMED    7637783
REFERENCE   2  (bases 1 to 2151)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nature. 
            1995 Aug 10. 376(6540):514-6."
COMMENT     Sequence Label: pBS-AMVpl-beta-1WT-nAchR
FEATURES             Location/Qualifiers
     source          1..2151
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 ttcccctggc ctgaggccgc tatccggaca aacttcactg agcgaaagag gcagggccat
       61 ggccttaggg gcgctgcttc tgcttctagg ggtactcggg acgcccctcg ccccaggcgc
      121 ccgcgggtcg gaagccgaag gccaactgat taagaaactt ttctccaact atgatagctc
      181 ggtgaggccg gcgcgggagg tgggagaccg cgtcggggtc agcatcggcc tcaccctggc
      241 gcaactcatc agcctgaacg agaaggatga agaaatgagc acaaaggtgt acttagacct
      301 ggagtggacc gactacaggt taagctggga ccccgcagaa catgatggca tcgattctct
      361 ccgcatcact gctgaatccg tttggctccc tgatgtggtg ctgctgaaca acaatgacgg
      421 aaatttcgac gttgccctgg acatcaatgt tgtggtatct ttcgagggct ctgtgcgctg
      481 gcaaccccct ggcctgtacc gcagcagctg cagcatccag gtcacctact tcccctttga
      541 ctggcagaac tgcaccatgg tgtttagttc ctacagctat gacagctctg aggtcagcct
      601 gaagacgggc ctggatcctg aaggagagga gaggcaggaa gtctacattc atgaagggac
      661 cttcattgag aatggccaat gggagattat ccacaaacct tctaggttaa tccaacttcc
      721 aggggatcag agaggtggga aggaagggca tcatgaggaa gttatcttct atctcattat
      781 tcggcggaag cctctcttct acctggtcaa cgtcattgcc ccatgcatcc tcatcacgct
      841 cctggccatc tttgtcttct acctcccacc agatgcagga gagaagatgg ggctctccat
      901 ctttgccctg ctgacgctca ctgtgttctt gctgctgttg gccgacaaag tgcctgagac
      961 ctccctggcg gtgcccatca ttatcaagta cctcatgttt accatggtcc ttgtcacctt
     1021 ctccgttatc cttagtgttg tggtcctcaa cctgcatcat cgctcacccc acacccacca
     1081 aatgcccttt tgggtccgcc agatcttcat tcacaagctc cctccatacc tgggtctgaa
     1141 gaggcccaaa cccgagagag accaactccc tgaaccacat cactctcttt ctccaagaag
     1201 tggctggggc agaggaactg atgaatattt catccggaag cctccaagtg attttctttt
     1261 ccctaaactt aacaggtttc agcctgaatc atctgccccg gacctgcgac gatttatcga
     1321 tggtccaacc cgggctgtag gtctgcctca ggagctacga gaggtcattt cctcaatcag
     1381 ctacatggcc cgacagcttc aggaacagga ggaccacgac gcactgaagg aggactggca
     1441 gtttgtggcc atggttgtgg accgtctttt tctgtggaca ttcatcgttt tcacaagcgt
     1501 cgggacccta gtcattttcc tagatgccac gtaccatttg ccccctcctg aacctttccc
     1561 ttgaggaccc tccggtcatt tttgccaaat gctgcaggta ctctcaagct caatagcgct
     1621 tggcgcttgt aagaatcttg tttctgggaa gacgttcaag tgagacttgg aggctgagca
     1681 tggtgccttg gacccacccg aaatgtcctt ctacttatta tttagagttt tgttcttctg
     1741 cggttttgtt tttgttgttt ttgagacaga gtctcactct gtggcccagg ctagcctgga
     1801 actgtggcgt ccaggctggt ctcaaactcc caacaatgtt acttccttag cctagcaatt
     1861 gttggaatca cagacctggt aaaccagcac acttggagtt tgtttcttga aactacatag
     1921 aatgtcacag cttagatctc tagtgaaata gaattataac caagtagtag actgtaagcc
     1981 ttttgaggac aggagatctg ttggctactg aattatcccc agcaatgtgt acaggtccta
     2041 gcccataagt gcttaacatt tgttgaagag agggaaaata aatctggaag gaaatataaa
     2101 tatcgcctac aattgcacgt attaaaatta aaatgtagaa aatgattaaa a
//
