LOCUS       sequence-211246-        1971 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Cation channelrhodopsin CsChR fused to mRuby2 fluorophore and 
            targeted to the neuronal soma and proximal dendrites.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1971)
  AUTHORS   Mardinly AR, Oldenburg IA, Pegard NC, Sridharan S, Lyall EH, Chesnov
            K, Brohawn SG, Waller L, Adesnik H
  TITLE     Precise multimodal optical control of neural ensemble activity.
  JOURNAL   Nat Neurosci. 2018 Apr 30. pii: 10.1038/s41593-018-0139-8. doi: 
            10.1038/s41593-018-0139-8.
  PUBMED    29713079
REFERENCE   2  (bases 1 to 1971)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nat 
            Neurosci. 2018 Apr 30. pii: 10.1038/s41593-018-0139-8. doi: 
            10.1038/s41593-018-0139-8."
COMMENT     Sequence Label: pCAG-CsChR-mRuby2-ST
FEATURES             Location/Qualifiers
     source          1..1971
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             1054..1764
                     /codon_start=1
                     /product="monomeric red fluorescent protein derived from 
                     mRuby, with improved photophysical properties (Lam et al., 
                     2012)"
                     /label=mRuby2
                     /translation="MVSKGEELIKENMRMKVVMEGSVNGHQFKCTGEGEGNPYMGTQTM
                     RIKVIEGGPLPFAFDILATSFMYGSRTFIKYPKGIPDFFKQSFPEGFTWERVTRYEDGG
                     VVTVMQDTSLEDGCLVYHVQVRGVNFPSNGPVMQKKTKGWEPNTEMMYPADGGLRGYTH
                     MALKVDGGGHLSCSFVTTYRSKKTVGNIKMPGIHAVDHRLERLEESDNEMFVVQREHAV
                     AKFAGLGGGMDELYK"
ORIGIN
        1 atgagcagac tggtcgccgc ttcttggctg ctggctctcc tcctctgcgg aattaccagc
       61 acaacaacag cctctagcgc cccagcagct tcttctacag acggaacagc cgccgcagca
      121 gtgtctcact acgccatgaa cggcttcgac gagctggcta aaggagccgt ggtgccagaa
      181 gaccactttg tctgcggacc agccgacaag tgctattgct ccgcttggct gcacagccac
      241 ggaagcaagg aggagaagac cgccttcacc gtcatgcagt ggatcgtgtt cgccgtctgc
      301 atcatcagcc tgctgttcta cgcctaccag acttggaggg ctacttgcgg ttgggaggag
      361 gtgtacgtga ccatcatcga gctggtccac gtctgcttcg gactctggca cgaggtcgat
      421 agcccttgta ccctgtacct gagcacaggc aacatggtcc tctggctgag atacgccgag
      481 tggctgctga cttgccccgt gatcctgatc cacctgagca acctgaccgg catgaagaac
      541 gactacaaca agcggaccat ggccctgctg gtgtcagacg tgggctgtat cgtgtgggga
      601 acaacagccg ccctgagcac cgatttcgtg aagatcatct tcttcttcct gggcctgctg
      661 tacggcttct acaccttcta cgccgccgcc aagatctaca tcgaggccta ccacaccgtg
      721 cccaagggca tttgtagaca gctcgtgcgg ctgcaggcct acgacttctt cttcacttgg
      781 agcatgttcc ccatcctgtt catggtcggc ccagagggat tcggcaagat caccgcctac
      841 agcagcggaa tcgcccacga agtgtgcgat ctgctgagca agaacctctg gggcctgatg
      901 ggccacttca tccgcgtgaa gatccacgag cacatcctgg tgcacggcaa catcaccaag
      961 aagaccaagg tcaacgtggc cggcgacatg gtggaactgg acacctacgt ggaccaggac
     1021 gaggaacacg acgagggagc ggccgcaccg gtaatggtgt ctaagggcga agagctgatc
     1081 aaggaaaata tgcgtatgaa ggtggtcatg gaaggttcgg tcaacggcca ccaattcaaa
     1141 tgcacaggtg aaggagaagg caatccgtac atgggaactc aaaccatgag gatcaaagtc
     1201 atcgagggag gacccctgcc atttgccttt gacattcttg ccacgtcgtt catgtatggc
     1261 agccgtactt ttatcaagta cccgaaaggc attcctgatt tctttaaaca gtcctttcct
     1321 gagggtttta cttgggaaag agttacgaga tacgaagatg gtggagtcgt caccgtcatg
     1381 caggacacca gccttgagga tggctgtctc gtttaccacg tccaagtcag aggggtaaac
     1441 tttccctcca atggtcccgt gatgcagaag aagaccaagg gttgggagcc taatacagag
     1501 atgatgtatc cagcagatgg tggtctgagg ggatacactc atatggcact gaaagttgat
     1561 ggtggtggcc atctgtcttg ctctttcgta acaacttaca ggtcaaaaaa gaccgtcggg
     1621 aacatcaaga tgcccggtat ccatgccgtt gatcaccgcc tggaaaggtt agaggaaagt
     1681 gacaatgaaa tgttcgtagt acaacgcgaa cacgcagttg ccaagttcgc cgggcttggt
     1741 ggtgggatgg acgagctgta caaggcccta gagcagtccc agcccatcct caacaccaag
     1801 gagatggccc cgcagagcaa gcctccagag gagctggaga tgagcagcat gcccagcccc
     1861 gtggcccctc tgcccgcacg cacggagggc gtcatcgaca tgcggagcat gtccagcatt
     1921 gacagcttca tcagctgtgc cacggacttc cctgaagcca ccagattcta a
//
