LOCUS       sequence-21374-e         762 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 762)
  AUTHORS   Isakoff SJ, Engelman JA, Irie HY, Luo J, Brachmann SM, Pearline RV, 
            Cantley LC, Brugge JS
  TITLE     Breast cancer-associated PIK3CA mutations are oncogenic in mammary 
            epithelial cells.
  JOURNAL   Cancer Res. 2005 Dec 1. 65(23):10992-1000.
  PUBMED    16322248
REFERENCE   2  (bases 1 to 762)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Cancer Res.
            2005 Dec 1. 65(23):10992-1000."
COMMENT     Sequence Label: JP1520 PIK3CA E545K HA
FEATURES             Location/Qualifiers
     source          1..762
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    complement(107..140)
                     /label=loxP
                     /bound_moiety="Cre recombinase"
                     /note="Cre-mediated recombination occurs in the 8-bp core 
                     sequence (ATGTATGC) (Shaw et al., 2021)."
ORIGIN
        1 gagctcgttt agtggaccgt cagatcgcct ggagacgcca tccacgctgt tttgacctcc
       61 atagaagaca ccgggaccga tccagcctcc gcggccccaa gcttcgataa cttcgtatag
      121 catacattat acgaagttat cagtcgacgg taccggacat atgcccggga attcctgcag
      181 gatccgctcg agaagcttgg taccgagctc ggatctcgag atgcctccaa gaccatcatc
      241 aggtgaactg tggggcatcc acttgatgcc cccaagaatc ctagtagaat gtttactacc
      301 aaatgggatg atagtgactt tagaatgcct ccgtgaggct acgttaataa cgataaagca
      361 tgaactattt aaagaagcaa gaaaataccc tctccatcaa cttcttcaag atgaatcttc
      421 ttacattttc gtaagtgtta cccaagaagc agaaagggaa gaattttttg atgaaacaag
      481 acgactttgt gaccttcggc tttttcaacc ctttttaaaa gtaattgaac cagtaggcaa
      541 ccgtgaagaa aagatcctca atcgagaaat tggttttgct atcggcatgc cagtgtgtga
      601 attcgatatg gttaaagatc cagaagtaca ggacttccga agaaatattc tcaatgtttg
      661 taaagaagct gtggatctta gggatcttaa ttcacctcat agtagagcaa tgtatgttta
      721 tcctcaaatg tagaatcttc accagaactg ccaaagcaca ta
//
