LOCUS       sequence-21717-e         700 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, 
            Ittmann M, Greenberg NM, Spencer DM
  TITLE     Conditional activation of fibroblast growth factor receptor (FGFR) 
            1, but not FGFR2, in prostate cancer cells leads to increased 
            osteopontin induction, extracellular signal-regulated kinase 
            activation, and in vivo proliferation.
  JOURNAL   Cancer Res. 2003 Oct 1. 63(19):6237-43.
  PUBMED    14559809
REFERENCE   2  (bases 1 to 700)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Cancer Res.
            2003 Oct 1. 63(19):6237-43."
COMMENT     Sequence Label: pSH1/M-FGFR1-Fv-Fvls-E
FEATURES             Location/Qualifiers
     source          1..700
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             complement(43..69)
                     /codon_start=1
                     /product="HA (human influenza hemagglutinin) epitope tag"
                     /label=HA
                     /translation="YPYDVPDYA"
     CDS             complement(94..414)
                     /codon_start=1
                     /product="F36V mutant of FK506-binding protein FKBP12"
                     /label=DmrB
                     /note="binds synthetic ligands that do not bind wild-type 
                     FKBP"
                     /translation="GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKVDSSRDRNKP
                     FKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL
                     KLE"
ORIGIN
        1 gntntgtctg gatcggtcat caatcaggaa ttcttagtcg agtgcgtagt ctggtacgtc
       61 gtacggatag tcgactccgg atccaccgcc agattccagt tttagaagct ccacatcgaa
      121 gacgagagtg gcatgtggtg ggatgatgcc tgggtgccca gtggcaccat aggcataatc
      181 tggagatata gtcagtttgg ctctctgacc cacactcatc tgggcaaccc cttcttccca
      241 gcctcggatc acctcctgct tgcctagcat aaacttaaag ggcttgtttc tgtcccggga
      301 ggaatcaact ttctttccat cttcaagcat cccggtgtag tgcaccacgc aggtctggcc
      361 gcgcttgggg aaggtgcgcc cgtctcctgg ggagatagtc tccacctgca ctccctcgac
      421 ttccagtttt agaagctcca catcgaagac gagagtggca tgtggtggga tgatgcctgg
      481 gtgcccagtg gcaccatagg cataatctgg agatatagtc agtttggctc tctgacccac
      541 actcatctgg gcaacccctt cttcccagcc tcggatcacc tcctgcttgc ctagcataaa
      601 cttaaagggc ttgtttctgt cngggggaga aatcattttt ctnnnatctt caagcanccc
      661 ggtgtagcnc accaccagcg cctgnaggag ncancccccc
//
