LOCUS       sequence-217302-       10974 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  pSMF2 with 8 CTD repeats.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 10974)
  AUTHORS   Morrill SA, Exner AE, Babokhov M, Reinfeld BI, Fuchs SM
  TITLE     DNA Instability Maintains the Repeat Length of the Yeast RNA 
            Polymerase II C-terminal Domain.
  JOURNAL   J Biol Chem. 2016 May 27;291(22):11540-50. doi: 
            10.1074/jbc.M115.696252. Epub 2016 Mar 29.
  PUBMED    27026700
REFERENCE   2  (bases 1 to 10974)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1074/jbc.M115.696252"; journalName: "J Biol Chem"; date: 
            "2016-05-27- 27"; volume: "291"; issue: "22"; pages: "11540-50"
COMMENT     Sequence Label: pRPB1-CTD8
FEATURES             Location/Qualifiers
     source          1..10974
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     primer_bind     complement(10..28)
                     /label=pBRforEco
                     /note="pBR322 vectors, upsteam of EcoRI site, forward 
                     primer"
     misc_feature    70..573
                     /label=CEN/ARS
                     /note="S. cerevisiae CEN6 centromere fused to an 
                     autonomously replicating sequence"
     promoter        610..714
                     /gene="bla"
                     /label=AmpR promoter
     CDS             join(715..783,784..1575)
                     /codon_start=1
                     /gene="bla"
                     /product="beta-lactamase"
                     /label=AmpR
                     /note="confers resistance to ampicillin, carbenicillin, and
                     related antibiotics"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     primer_bind     complement(933..952)
                     /label=Amp-R
                     /note="Ampicillin resistance gene, reverse primer"
     rep_origin      1746..2334
                     /direction=RIGHT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     2235..2254
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     primer_bind     2488..2505
                     /label=L4440
                     /note="L4440 vector, forward primer"
     protein_bind    2622..2643
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     promoter        join(2658..2663,2664..2681,2682..2688)
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    2696..2712
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     primer_bind     2701..2723
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     primer_bind     2720..2736
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     2720..2736
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     CDS             8136..8201
                     /codon_start=1
                     /product="three tandem FLAG(R) epitope tags, followed by an
                     enterokinase cleavage site"
                     /label=3xFLAG
                     /translation="DYKDHDGDYKDHDINYKDDDDK"
     promoter        8811..9216
                     /gene="S. cerevisiae LEU2"
                     /label=LEU2 promoter
     CDS             9217..10311
                     /codon_start=1
                     /gene="S. cerevisiae LEU2"
                     /product="3-isopropylmalate dehydrogenase, required for 
                     leucine biosynthesis"
                     /label=LEU2
                     /note="yeast auxotrophic marker"
                     /translation="MSAPKKIVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHL
                     IGGAAIDATGVPLPDEALEASKKADAVLLGAVGGPKWGTGSVRPEQGLLKIRKELQLYA
                     NLRPCNFASDSLLDLSPIKPQFAKGTDFVVVRELVGGIYFGKRKEDDGDGVAWDSEQYT
                     VPEVQRITRMAAFMALQHEPPLPIWSLDKANVLASSRLWRKTVEETIKNEFPTLKVQHQ
                     LIDSAAMILVKNPTHLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAF
                     GLYEPCHGSAPDLPKNKVNPIATILSAAMMLKLSLNLPEEGKAIEDAVKKVLDAGIRTG
                     DLGGSNSTTEVGDAVAEEVKKILA"
     primer_bind     complement(10805..10824)
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
     primer_bind     10924..10946
                     /label=pGEX 3'
                     /note="pGEX vectors, reverse primer"
ORIGIN
        1 gacgaaaggg cctcgtgata cgcctatttt tataggttaa tgtcatgata ataatggttt
       61 cttaggacgg atcgcttgcc tgtaacttac acgcgcctcg tatcttttaa tgatggaata
      121 atttgggaat ttactctgtg tttatttatt tttatgtttt gtatttggat tttagaaagt
      181 aaataaagaa ggtagaagag ttacggaatg aagaaaaaaa aataaacaaa ggtttaaaaa
      241 atttcaacaa aaagcgtact ttacatatat atttattaga caagaaaagc agattaaata
      301 gatatacatt cgattaacga taagtaaaat gtaaaatcac aggattttcg tgtgtggtct
      361 tctacacaga caagatgaaa caattcggca ttaatacctg agagcaggaa gagcaagata
      421 aaaggtagta tttgttggcg atccccctag agtcttttac atcttcggaa aacaaaaact
      481 attttttctt taatttcttt ttttactttc tatttttaat ttatatattt atattaaaaa
      541 atttaaatta taattatttt tatagcacgt gatgaaaagg acccaggtgg cacttttcgg
      601 ggaaatgtgc gcggaacccc tatttgttta tttttctaaa tacattcaaa tatgtatccg
      661 ctcatgagac aataaccctg ataaatgctt caataatatt gaaaaaggaa gagtatgagt
      721 attcaacatt tccgtgtcgc ccttattccc ttttttgcgg cattttgcct tcctgttttt
      781 gctcacccag aaacgctggt gaaagtaaaa gatgctgaag atcagttggg tgcacgagtg
      841 ggttacatcg aactggatct caacagcggt aagatccttg agagttttcg ccccgaagaa
      901 cgttttccaa tgatgagcac ttttaaagtt ctgctatgtg gcgcggtatt atcccgtatt
      961 gacgccgggc aagagcaact cggtcgccgc atacactatt ctcagaatga cttggttgag
     1021 tactcaccag tcacagaaaa gcatcttacg gatggcatga cagtaagaga attatgcagt
     1081 gctgccataa ccatgagtga taacactgcg gccaacttac ttctgacaac gatcggagga
     1141 ccgaaggagc taaccgcttt tttgcacaac atgggggatc atgtaactcg ccttgatcgt
     1201 tgggaaccgg agctgaatga agccatacca aacgacgagc gtgacaccac gatgcctgta
     1261 gcaatggcaa caacgttgcg caaactatta actggcgaac tacttactct agcttcccgg
     1321 caacaattaa tagactggat ggaggcggat aaagttgcag gaccacttct gcgctcggcc
     1381 cttccggctg gctggtttat tgctgataaa tctggagccg gtgagcgtgg gtctcgcggt
     1441 atcattgcag cactggggcc agatggtaag ccctcccgta tcgtagttat ctacacgacg
     1501 gggagtcagg caactatgga tgaacgaaat agacagatcg ctgagatagg tgcctcactg
     1561 attaagcatt ggtaactgtc agaccaagtt tactcatata tactttagat tgatttaaaa
     1621 cttcattttt aatttaaaag gatctaggtg aagatccttt ttgataatct catgaccaaa
     1681 atcccttaac gtgagttttc gttccactga gcgtcagacc ccgtagaaaa gatcaaagga
     1741 tcttcttgag atcctttttt tctgcgcgta atctgctgct tgcaaacaaa aaaaccaccg
     1801 ctaccagcgg tggtttgttt gccggatcaa gagctaccaa ctctttttcc gaaggtaact
     1861 ggcttcagca gagcgcagat accaaatact gttcttctag tgtagccgta gttaggccac
     1921 cacttcaaga actctgtagc accgcctaca tacctcgctc tgctaatcct gttaccagtg
     1981 gctgctgcca gtggcgataa gtcgtgtctt accgggttgg actcaagacg atagttaccg
     2041 gataaggcgc agcggtcggg ctgaacgggg ggttcgtgca cacagcccag cttggagcga
     2101 acgacctaca ccgaactgag atacctacag cgtgagctat gagaaagcgc cacgcttccc
     2161 gaagggagaa aggcggacag gtatccggta agcggcaggg tcggaacagg agagcgcacg
     2221 agggagcttc cagggggaaa cgcctggtat ctttatagtc ctgtcgggtt tcgccacctc
     2281 tgacttgagc gtcgattttt gtgatgctcg tcaggggggc ggagcctatg gaaaaacgcc
     2341 agcaacgcgg cctttttacg gttcctggcc ttttgctggc cttttgctca catgttcttt
     2401 cctgcgttat cccctgattc tgtggataac cgtattaccg cctttgagtg agctgatacc
     2461 gctcgccgca gccgaacgac cgagcgcagc gagtcagtga gcgaggaagc ggaagagcgc
     2521 ccaatacgca aaccgcctct ccccgcgcgt tggccgattc attaatgcag ctggcacgac
     2581 aggtttcccg actggaaagc gggcagtgag cgcaacgcaa ttaatgtgag ttagctcact
     2641 cattaggcac cccaggcttt acactttatg cttccggctc gtatgttgtg tggaattgtg
     2701 agcggataac aatttcacac aggaaacagc tatgaccatg attacgccaa gcgcgcgggt
     2761 tgcgcgtctc gaggagcgtg cagcaccatt caccgccagc tttgtatcgt cctttagagt
     2821 gcagcaagaa cattaattgc tctcacagag gtatcataag aacatccgat tcgttcatta
     2881 actgaaatca tatctgtgtt gttctgatcg actctctttg ttagttttat cttccatttt
     2941 tttttattcc tttcattttc caataaaatt tgaacaggat cgatataaac agataaaaac
     3001 cctccaaagt taaccatttg tttatatttg cttttctgca taagttttcc tagcgaattc
     3061 cctgatcaac tttcaaggaa aactaaaact actgtattat aagaggtttt ttttttcatt
     3121 ccagattaat tttgaaatac gatatcctca agtttatcta ccagaatatt tgactaagaa
     3181 atcaaactct gttaataata atataattat aaaaacctca actagaaact ccaaaaaaaa
     3241 aaatttacca ttttttactt tctatccttg ttaaccaaat ttcaaaaaaa ttttaccttt
     3301 tctttttcca gaagagggac caatcataaa gatagcaata acactttacc ccaaaatata
     3361 aatcagacat ggtaggacaa cagtattcta gtgctccact ccgtacagta aaagaggtcc
     3421 aattcggtct tttctcacct gaagaagtta gagcaatcag tgtggccaaa attagatttc
     3481 cagagacaat ggatgaaacc cagacgagag cgaaaattgg tggtctaaac gaccctaggt
     3541 taggctctat tgatcgtaat ctgaagtgtc aaacttgtca agagggtatg aacgaatgtc
     3601 ctggtcattt tggtcacata gatttagcaa aacctgtatt tcatgttggt tttattgcca
     3661 aaattaagaa agtatgtgag tgtgtctgta tgcactgtgg taagctatta ctggatgaac
     3721 ataatgaatt aatgagacaa gctctagcaa tcaaagacag taaaaaaagg tttgctgcaa
     3781 tttggacttt atgtaaaaca aaaatggtct gcgaaacaga tgtcccttct gaagatgatc
     3841 ctactcagct cgtatcaagg ggaggttgtg gtaatacaca gcctacaatt cgtaaggatg
     3901 ggttgaaatt agttggtagt tggaaaaaag atagagccac gggggatgcg gatgaaccag
     3961 aactaagagt tttaagtacg gaggaaatct tgaatatttt taagcatatc tcagtaaaag
     4021 acttcactag tttgggtttc aacgaagttt tttctcgtcc agaatggatg attttaacat
     4081 gccttcctgt cccaccacca ccggtgcgtc catccatttc cttcaatgaa tctcaaagag
     4141 gtgaggatga tttaaccttt aaacttgctg atattttaaa agctaatatt agtttggaaa
     4201 cactagagca taacggtgct ccacatcatg ctattgaaga agcagagagt ttattacaat
     4261 ttcatgttgc cacttatatg gataatgata ttgctggtca accacaagct cttcaaaagt
     4321 ccggccgtcc cgttaaatct attcgtgctc gtttgaaggg taaagagggt cgtatcagag
     4381 gtaatttaat gggtaagcgt gtggattttt cggcaagaac tgttatttct ggtgatccta
     4441 atttggaatt agaccaagtc ggtgttccaa aatctattgc caagacttta acatacccag
     4501 aagtggtcac accatataac atagatcgtc tgacgcaact tgttaggaat ggaccaaatg
     4561 agcaccccgg tgccaaatac gtcattcgtg atagcggaga ccgtatagat ttaagataca
     4621 gtaaaagggc aggtgatatt caattacagt atgggtggaa agttgaacgt catattatgg
     4681 acaatgatcc agttttattc aaccgtcaac cttcgttgca caaaatgtcc atgatggccc
     4741 acagagtaaa agttattcca tattctacat ttagattgaa tttgtccgtt acatctccat
     4801 acaatgccga tttcgacggt gacgaaatga atcttcacgt tcctcagtct gaggaaacaa
     4861 gggcggaact ttctcaatta tgtgctgttc ctctgcaaat tgtttcacca caatctaaca
     4921 aaccttgtat gggtattgtt caagatactt tgtgtggtat tcgtaaactg acattaagag
     4981 atacatttat agaacttgat caagttttga atatgcttta ttgggttcca gattgggatg
     5041 gtgttattcc gacacctgca attatcaagc ccaaaccttt gtggtccggt aaacaaatct
     5101 tgtctgtggc tatcccaaac ggtattcatt tacaacgttt tgatgagggc actactctgc
     5161 tttctccaaa ggataatggt atgcttatta ttgacggtca aatcattttt ggtgtagtag
     5221 agaaaaaaac cgttggttcc tccaatggtg gtttaattca tgttgttacg agagaaaagg
     5281 gacctcaagt ttgtgctaag ttgtttggta acatacagaa agttgttaac ttttggttac
     5341 tacataatgg gttttcaaca ggtattggtg ataccattgc ggacggccca acaatgaggg
     5401 aaattacaga gacaattgca gaggctaaaa agaaagtttt ggatgttacg aaagaagccc
     5461 aggcaaactt attgactgct aaacatggta tgactctccg tgagtctttt gaggataacg
     5521 ttgttcggtt cctaaatgaa gcaagagata aggcaggtcg tttagctgaa gtcaatttga
     5581 aagatttgaa caatgtgaaa caaatggtta tggcaggttc caagggttca tttattaata
     5641 tcgcgcaaat gtcagcttgt gtaggacagc aatctgttga aggtaaacgt attgcttttg
     5701 ggttcgttga tcgtacctta cctcatttct ctaaagatga ttactcccca gagtctaaag
     5761 gttttgttga gaactcatat ttgagaggtt tgaccccaca agaatttttt ttccatgcaa
     5821 tgggtggtcg tgaaggtctt atcgataccg ccgtcaaaac agccgaaaca ggttatattc
     5881 aacgtcgttt agtgaaagct ctagaagata tcatggttca ttacgataac accacaagaa
     5941 actcattggg taacgttatt cagtttattt atggtgaaga tggtatggat gctgcgcata
     6001 ttgaaaagca atcgctagat actattggtg gctccgatgc agcttttgaa aagagataca
     6061 gagttgattt attgaataca gaccataccc ttgatccctc actattggaa tccggatctg
     6121 agatacttgg cgatttgaaa cttcaagttc tcctggatga agaatacaaa caattagtga
     6181 aagatcgtaa atttttgagg gaagtttttg ttgatggtga agcaaactgg ccattaccag
     6241 tcaacataag acgtattatt caaaatgctc aacaaacttt ccacatagat catacgaaac
     6301 catctgattt aacaatcaaa gacatcgttc ttggtgtaaa ggatttgcaa gaaaacttat
     6361 tagtgttgcg tggtaagaat gaaattatac aaaatgccca gcgagatgca gttacattgt
     6421 tctgctgttt attacgttcc cgtttggcca cacgtagagt tctacaagag tacagactaa
     6481 caaaacaggc attcgattgg gtattaagta atatcgaggc acaattcctc cgttctgttg
     6541 ttcaccctgg tgaaatggtt ggtgttctag cagcccaatc cattggtgaa ccagccacac
     6601 aaatgaccct taacaccttc cattttgctg gtgttgcttc caaaaaagtt acttctggtg
     6661 tcccccgttt aaaggaaatt ttgaatgtgg ccaaaaacat gaaaacccct tccttgactg
     6721 tatacttaga gcctggtcat gctgccgatc aagaacaagc gaagttgatc agatctgcta
     6781 tcgagcatac cactttaaag agtgtcacta ttgcttcaga aatttactat gatcctgatc
     6841 cacgttccac agttattcca gaagatgaag aaattatcca acttcatttc tcattattgg
     6901 atgaagaggc tgaacaatct tttgaccaac aatcaccttg gttattacgt ctggaactgg
     6961 atcgtgcagc aatgaatgat aaagacttaa caatgggtca ggttggtgaa agaatcaagc
     7021 aaacattcaa aaatgatttg tttgttatct ggtctgaaga caacgatgag aagttgatca
     7081 tccgttgtcg tgttgttcgt ccaaagtcac tagatgctga gactgaagca gaagaagatc
     7141 atatgttgaa gaaaattgag aacacaatgt tagagaatat tacattacgt ggtgtagaga
     7201 acatcgagcg tgttgtcatg atgaaatatg accgtaaagt accaagtcca actggtgaat
     7261 acgttaagga acctgaatgg gtgttggaaa cagatggtgt taacttatct gaagttatga
     7321 ctgttcctgg tatcgaccca accagaatct ataccaactc cttcattgat ataatggaag
     7381 ttctaggtat tgaagctggt cgtgcagcct tgtataaaga agtttacaat gttattgctt
     7441 ctgatggttc gtatgttaac taccgtcata tggctttgtt agtcgatgtt atgacaaccc
     7501 aaggtggctt aacttctgtt actcgtcatg gtttcaacag atcaaataca ggtgccttaa
     7561 tgagatgttc atttgaagaa actgtcgaaa ttttgtttga agctggtgct tcagccgaat
     7621 tagatgattg tcgtggtgtt tcggaaaatg tcattcttgg tcaaatggct ccaatcggta
     7681 ccggtgcatt tgatgtgatg atcgatgagg agtcactggt aaaatacatg ccagaacaaa
     7741 aaataactga gattgaagac ggacaagatg gtggcgtcac accatacagt aacgaaagtg
     7801 gtttggtcaa tgcagatctt gacgttaaag atgagctaat gttttcacct ctggttgatt
     7861 cgggttcaaa tgacgctatg gctggaggat ttacagcgta cggtggtgct gattatggtg
     7921 aagccacgtc tccatttggt gcttatggtg aagcacctac atctcccggg tttggagtct
     7981 tgacaccagg cttttctccg acgtctccta gttacagccc aacctcacct tcatattctc
     8041 cgacgtctcc tagttacagc ccaacctcac cttcatattc tccgacgtct cctagttaca
     8101 gcccaacctc accttcatat tctccgacgt ctcctgacta caaagaccat gacggtgatt
     8161 ataaagatca tgacatcaac tacaaggatg acgatgacaa gtgagctcgt atatcatcct
     8221 tacgtatttg acgttattac attatatata gtttctcaaa taatatttct agtttatttt
     8281 tgtatcataa taaaaacgta taccaaatat accattattt ttcatagcat tatggtaggg
     8341 atagggaatc aagtaactaa tttatatccg cagagcattg ggaaaaccaa cggcgctagt
     8401 aaatgcattt aaattacgtc cgtccaactt ctaagcttca agtggtagac tcttaactct
     8461 gaaccttttt agcaattaag ctcttgaaga tatcaaaagt gttaccgtcc ggctgtaaat
     8521 tataaacgtt tcctgtaaat tgagtggaac taccgcttac caattctttt gcaatcagta
     8581 aaccgtagtc ttccgtgata ccagtaatca tggcttgcgt atttccgtga tctggtaatg
     8641 ttactatttg gttactatgt aaccacaact cataataact tggcaatatt tccgcagctc
     8701 cgtagttaat aaactgtttt aatatgacct caaggttatt catatagagt gcctgcgggc
     8761 ccgatcccga tatccaggcc tcccgatatc caggcctcag cttagcctag aactgtggga
     8821 atactcaggt atcgtaagat gcaagagttc gaatctctta gcaaccatta tttttttcct
     8881 caacataacg agaacacaca ggggcgctat cgcacagaat caaattcgat gactggaaat
     8941 tttttgttaa tttcagaggt cgcctgacgc atataccttt ttcaactgaa aaattgggag
     9001 aaaaaggaaa ggtgagagcg ccggaaccgg cttttcatat agaatagaga agcgttcatg
     9061 actaaatgct tgcatcacaa tacttgaagt tgacaatatt atttaaggac ctattgtttt
     9121 ttccaatagg tggttagcaa tcgtcttact ttctaacttt tcttaccttt tacatttcag
     9181 caatatatat atatatttca aggatatacc attctaatgt ctgcccctaa gaagatcgtc
     9241 gttttgccag gtgaccacgt tggtcaagaa atcacagccg aagccattaa ggttcttaaa
     9301 gctatttctg atgttcgttc caatgtcaag ttcgatttcg aaaatcattt aattggtggt
     9361 gctgctatcg atgctacagg tgttccactt ccagatgagg cgctggaagc ctccaagaag
     9421 gctgatgccg ttttgttagg tgctgtgggt ggtcctaaat ggggtacagg tagtgttaga
     9481 cctgaacaag gtttactaaa aatccgtaaa gaacttcaat tgtacgccaa cttaagacca
     9541 tgtaactttg catccgactc tcttttagac ttatctccaa tcaagccaca atttgctaaa
     9601 ggtactgact tcgttgttgt cagagaatta gtgggaggta tttactttgg taagagaaag
     9661 gaagacgatg gtgatggtgt cgcttgggat agtgaacaat acaccgttcc agaagtgcaa
     9721 agaatcacaa gaatggccgc tttcatggcc ctacaacatg agccaccatt gcctatttgg
     9781 tccttggata aagctaatgt tttggcctct tcaagattat ggagaaaaac tgtggaggaa
     9841 accatcaaga acgaatttcc tacattgaag gttcaacatc aattgattga ttctgccgcc
     9901 atgatcctag ttaagaaccc aacccaccta aatggtatta taatcaccag caacatgttt
     9961 ggtgatatca tctccgatga agcctccgtt atcccaggtt ccttgggttt gttgccatct
    10021 gcgtccttgg cctctttgcc agacaagaac accgcatttg gtttgtacga accatgccac
    10081 ggttctgctc cagatttgcc aaagaataag gtcaacccta tcgccactat cttgtctgct
    10141 gcaatgatgt tgaaattgtc attgaacttg cctgaagaag gtaaggccat tgaagatgca
    10201 gttaaaaagg ttttggatgc aggtatcaga actggtgatt taggtggttc caacagtacc
    10261 accgaagtcg gtgatgctgt cgccgaagaa gttaagaaaa tccttgctta aaaagattct
    10321 ctttttttat gatatttgta cataaacttt ataaatgaaa ttcataatag aaacgacacg
    10381 aaattacaaa atggaatatg ttcatagggt agacgaaact atatacgcaa tctacataca
    10441 tttatcaaga aggagaaaaa ggaggatgta aaggaataca ggtaagcaaa ttgatactaa
    10501 tggctcaacg tgataaggaa aaagaattgc actttaacat taatattgac aaggaggagg
    10561 gcaccacaca aaaagttagg tgtaacagaa aatcatgaaa ctatgattcc taatttatat
    10621 attggaggat tttctctaaa aaaaaaaaaa tacaacaaat aaaaaacact caatgacctg
    10681 accatttgat ggagtttaag tcaatacctt cttgaaccat ttcccataat ggtgaaagtt
    10741 ccctcaagaa ttttactctg tcagaaacgg ccttaacgac gtagtcgata tggtgcactc
    10801 tcagtacaat ctgctctgat gccgcatagt taagccagcc ccgacacccg ccaacacccg
    10861 ctgacgcgcc ctgacgggct tgtctgctcc cggcatccgc ttacagacaa gctgtgaccg
    10921 tctccgggag ctgcatgtgt cagaggtttt caccgtcatc accgaaacgc gcga
//
