LOCUS       sequence-229530-        6551 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 6551)
  AUTHORS   Pastan I, Gottesman MM, Ueda K, Lovelace E, Rutherford AV, 
            Willingham MC
  TITLE     A retrovirus carrying an MDR1 cDNA confers multidrug resistance and 
            polarized expression of P-glycoprotein in MDCK cells.
  JOURNAL   Proc Natl Acad Sci U S A. 1988 Jun . 85(12):4486-90.
  PUBMED    2898143
REFERENCE   2  (bases 1 to 6551)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Proc Natl 
            Acad Sci U S A. 1988 Jun . 85(12):4486-90."
COMMENT     Sequence Label: pHaMDRwt
FEATURES             Location/Qualifiers
     source          1..6551
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     LTR             333..925
                     /note="long terminal repeat from Moloney murine leukemia 
                     virus"
ORIGIN
        1 actagtgaga gacagcatgg ccaaattgag agagaggctg aatcagagac agaaactgtt
       61 tgagtcaact caaagatggt ttgagggact gtttaacaga tccccttggt ttaccacctt
      121 gatatctacc attatgggac ccctcattgt actcctaatg attttgctct tcggaccctg
      181 cattcttaat cgattaagtc caatttgtta aagacaggat atcagtggtc caggctctag
      241 ttttgactca acaatatcac cagctgaagc ctatagagta cgagccatag ataaaataaa
      301 agattttatt tagtctccag aaaaaagggg ggaatgaaag accccacctg taggtttggc
      361 aagctagctt aagtaacgcc attttacaag gcatggaaaa atacataact gagaatagag
      421 aagttcagat caaggtcagg aacagagaaa cagctgaata tgggccaaac aggatatctg
      481 tggtaagcag ttcctgcccc ggcccagggc caagaacaga tagaacagct gaatatgggc
      541 caaacaggat atctgtggta agcagttcct gccccggctc agggccaaga acagatggtc
      601 cccagatgcg gtccagccct cagcagtttc tagagaacca tcagatgttt ccagggtgcc
      661 ccaaggacct gaaatgaccc tgtgccttat ttaaactaac caatcagttc gcttctcgct
      721 tctgttcgcg cgcttctgct ccccgagctc aataaaagag cccacaaccc ctcactcggg
      781 gcgccagtcc tccgattgac tgagtcgccc gggtacccgt atatccaata aaccctcttg
      841 cagttgcatc cgacttgtgg tctcgctgtt ccttgggagg gtctcctcta agtgattgac
      901 tacccgttag tgggggtctt tcatttgggg gctcgtccgg gatcgggaga cccctgccca
      961 gggaccaccg acccaccacc gggaggcaag ccggccggcg tttgtcttgt ctgttgtgtc
     1021 ttgtcctgtg aacgatcgat caataggctc agatctgggg actatctggg cgggccagag
     1081 aaggagctga cgagctcgga cttctccccc gcagccctgg aagacgttcc aagggtggtt
     1141 ggaggagagg gagatccgga tccgtggcac ctccgtccgt tttcggaggg atccgcaccc
     1201 ttgatgactc cgtctgaatt tttggtttca gtttggtacc gaagctgcgc ggcgcgtctg
     1261 cttgttactt gtttgactgt tggaattgtt tgtcttcttt gtgacctgac tgtggttttc
     1321 tggacgtgtt gtgtctgtta gtgtcttttt gacttttgtt tcgtgtttga atttggactg
     1381 acgactgtgt ttaaaatctt agaccgacga ctgtgtttga aatcatgaaa ctgtttgctt
     1441 tgttcgtcga agagttttac ttggtcccct taacgcttag tgagtaagaa acttaatttt
     1501 gtagaccccg ctctagtggc agtgtgttgg ttgatagcca aagttaattt ttaaaacata
     1561 gtgttttggg ggttggggat ttagctcagt gatagagctc ttgcctagca agcgcaaggc
     1621 cctgggttcg gtccccagct ctgaaaaaaa ggaaagagaa acaaaacaaa aacatatagt
     1681 gttttatctg tgcttatgcc cgcagcccga gccgcacccg ccgcggtggc attcgagtag
     1741 cggctcttcc aagctcaaag aagcagaggc cgctgttcgt ttcctttagg tctttccact
     1801 aaagtcggag tatcttcttc caaaatttca cgtcttggtg gccgttccaa ggagcgcgag
     1861 gtcgggatgg atcttgaagg ggaccgcaat ggaggagcaa agaagaagaa cttttttaaa
     1921 ctgaacaata aaagtgaaaa agataagaag gaaaagaaac caactgtcag tgtattttca
     1981 atgtttcgct attcaaattg gcttgacaag ttgtatatgg tggtgggaac tttggctgcc
     2041 atcatccatg gggctggact tcctctcatg atgctggtgt ttggagaaat gacagatatc
     2101 tttgcaaatg caggaaattt agaagatctg atgtcaaaca tcactaatag aagtgatatc
     2161 aatgatacag ggttcttcat gaatctggag gaagacatga ccaggtatgc ctattattac
     2221 agtggaattg gtgctggggt gctggttgct gcttacattc aggtttcatt ttggtgcctg
     2281 gcagctggaa gacaaataca caaaattaga aaacagtttt ttcatgctat aatgcgacag
     2341 gagataggct ggtttgatgt gcacgatgtt ggggagctta acacccgact tacagatgat
     2401 gtctccaaga ttaatgaagg aattggtgac aaaattggaa tgttctttca gtcaatggca
     2461 acatttttca ctgggtttat agtaggattt acacgtggtt ggaagctaac ccttgtgatt
     2521 ttggccatca gtcctgttct tggactgtca gctgctgtct gggcaaagat actatcttca
     2581 tttactgata aagaactctt agcgtatgca aaagctggag cagtagctga agaggtcttg
     2641 gcagcaatta gaactgtgat tgcatttgga ggacaaaaga aagaacttga aaggtacaac
     2701 aaaaatttag aagaagctaa aagaattggg ataaagaaag ctattacagc caatatttct
     2761 ataggtgctg ctttcctgct gatctatgca tcttatgctc tggccttctg gtatgggacc
     2821 accttggtcc tctcagggga atattctatt ggacaagtac tcactgtatt cttttctgta
     2881 ttaattgggg cttttagtgt tggacaggca tctccaagca ttgaagcatt tgcaaatgca
     2941 agaggagcag cttatgaaat cttcaagata attgataata agccaagtat tgacagctat
     3001 tcgaagagtg ggcacaaacc agataatatt aagggaaatt tggaattcag aaatgttcac
     3061 ttcagttacc catctcgaaa agaagttaag atcttgaagg gtctgaacct gaaggtgcag
     3121 agtgggcaga cggtggccct ggttggaaac agtggctgtg ggaagagcac aacagtccag
     3181 ctgatgcaga ggctctatga ccccacagag gggatggtca gtgttgatgg acaggatatt
     3241 aggaccataa atgtaaggtt tctacgggaa atcattggtg tggtgagtca ggaacctgta
     3301 ttgtttgcca ccacgatagc tgaaaacatt cgctatggcc gtgaaaatgt caccatggat
     3361 gagattgaga aagctgtcaa ggaagccaat gcctatgact ttatcatgaa actgcctcat
     3421 aaatttgaca ccctggttgg agagagaggg gcccagttga gtggtgggca gaagcagagg
     3481 atcgccattg cacgtgccct ggttcgtaac cccaagatcc tcctgctgga tgaggccacg
     3541 tcagccttgg acacagaaag cgaagcagtg gttcaggtgg ctctggataa ggccagaaaa
     3601 ggtcggacca ccattgtgat agctcatcgt ttgtctacag ttcgtaatgc tgacgtcatc
     3661 gctggtttcg atgatggagt cattgtggag aaaggaaatc atgatgaact catgaaagag
     3721 aaaggcattt acttcaaact tgtcacaatg cagacagcag gaaatgaagt tgaattagaa
     3781 aatgcagctg atgaatccaa aagtgaaatt gatgccttgg aaatgtcttc aaatgattca
     3841 agatccagtc taataagaaa aagatcaact cgtaggagtg tccgtggatc acaagcccaa
     3901 gacagaaagc ttagtaccaa agaggctctg gatgaaagta tacctccagt ttccttttgg
     3961 aggattatga agctaaattt aactgaatgg ccttattttg ttgttggtgt attttgtgcc
     4021 attataaatg gaggcctgca accagcattt gcaataatat tttcaaagat tataggggtt
     4081 tttacaagaa ttgatgatcc tgaaacaaaa cgacagaata gtaacttgtt ttcactattg
     4141 tttctagccc ttggaattat ttcttttatt acatttttcc ttcagggttt cacatttggc
     4201 aaagctggag agatcctcac caagcggctc cgatacatgg ttttccgatc catgctcaga
     4261 caggatgtga gttggtttga tgaccctaaa aacaccactg gagcattgac taccaggctc
     4321 gccaatgatg ctgctcaagt taaaggggct ataggttcca ggcttgctgt aattacccag
     4381 aatatagcaa atcttgggac aggaataatt atatccttca tctatggttg gcaactaaca
     4441 ctgttactct tagcaattgt acccatcatt gcaatagcag gagttgttga aatgaaaatg
     4501 ttgtctggac aagcactgaa agataagaaa gaactagaag gtgctgggaa gatcgctact
     4561 gaagcaatag aaaacttccg aaccgttgtt tctttgactc aggagcagaa gtttgaacat
     4621 atgtatgctc agagtttgca ggtaccatac agaaactctt tgaggaaagc acacatcttt
     4681 ggaattacat tttccttcac ccaggcaatg atgtattttt cctatgctgg atgtttccgg
     4741 tttggagcct acttggtggc acataaactc atgagctttg aggatgttct gttagtattt
     4801 tcagctgttg tctttggtgc catggccgtg gggcaagtca gttcatttgc tcctgactat
     4861 gccaaagcca aaatatcagc agcccacatc atcatgatca ttgaaaaaac ccctttgatt
     4921 gacagctaca gcacggaagg cctaatgccg aacacattgg aaggaaatgt cacatttggt
     4981 gaagttgtat tcaactatcc cacccgaccg gacatcccag tgcttcaggg actgagcctg
     5041 gaggtgaaga agggccagac gctggctctg gtgggcagca gtggctgtgg gaagagcaca
     5101 gtggtccagc tcctggagcg gttctacgac cccttggcag ggaaagtgct gcttgatggc
     5161 aaagaaataa agcgactgaa tgttcagtgg ctccgagcac acctgggcat cgtgtcccag
     5221 gagcccatcc tgtttgactg cagcattgct gagaacattg cctatggaga caacagccgg
     5281 gtggtgtcac aggaagagat cgtgagggca gcaaaggagg ccaacataca tgccttcatc
     5341 gagtcactgc ctaataaata tagcactaaa gtaggagaca aaggaactca gctctctggt
     5401 ggccagaaac aacgcattgc catagctcgt gcccttgtta gacagcctca tattttgctt
     5461 ttggatgaag ccacgtcagc tctggataca gaaagtgaaa aggttgtcca agaagccctg
     5521 gacaaagcca gagaaggccg cacctgcatt gtgattgctc accgcctgtc caccatccag
     5581 aatgcagact taatagtggt gtttcagaat ggcagagtca aggagcatgg cacgcatcag
     5641 cagctgctgg cacagaaagg catctatttt tcaatggtca gtgtccaggc tggaacaaag
     5701 cgccagtgaa ctctgactgt atgagatgtt aaatactttt taatatttgt ttagatatga
     5761 catttattca aagttaaaag caaacactta cagaattatg aagaggtatc tgtttaacag
     5821 cttaattaat taagctcgag ggtcagtcat gtcctttgtg cccgtcccgg cacaggctca
     5881 ggacgaggag gtgccggatg cagggaggta ggtactcctt aagggaaaat ctaagcccag
     5941 agagacagcc ggtaacagct aggctgcctc tctgctcgcc tttctgtttc atagacaaag
     6001 cttgtgctta tatttacagt ggcctttttg tccaaaaaaa ggcctcctgg tttagctgtg
     6061 tgactaaatg ctatttgtcc tcttcagtgg acctctctcc tctagattcc cttcttgttt
     6121 tctcaccatc ccacgtgaga tgcttgttag taactgttac agatcttctt taccactgag
     6181 gaaagacaga atcctgctaa aggccagaaa gaatgttcca gacatggatg gaaggctcct
     6241 gactgttgac ttcaatgccc ctgaaggtag ggagtgctcc aggtctgccc ccaggctccg
     6301 agggtgggtc tcctaggggc tagaaaatgc cccaccaatc tggctaagat aagaaaaaga
     6361 tataaagaga aagttacaga aacttgaagg gtaaagctaa gtcactgaaa gagttattat
     6421 aagttacaga gaaaataagt tgatgcgtgg ttcagggtct gtgcagaaaa gtggacagat
     6481 aaaaagaaca agaagctaga gaaaaaaaaa aaaaaaaaaa aaaattagag agctaaagag
     6541 agataaaaga c
//
