LOCUS       sequence-243638-       34694 bp    DNA     circular UNA 15-DEC-2025
DEFINITION  It can be used to construct a recombinant virus carrying other 
            transgene or an adenovector with modified fiber..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 34694)
  AUTHORS   Liu H, Lu Z, Zhang X, Guo X, Mei L, Zou X, Zhong Y, Wang M, Hung T
  TITLE     Single plasmid-based, upgradable and backward compatible adenoviral 
            vector systems.
  JOURNAL   Hum Gene Ther. 2019 Feb 22. doi: 10.1089/hum.2018.258.
  PUBMED    30793964
REFERENCE   2  (bases 1 to 34694)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Hum Gene 
            Ther. 2019 Feb 22. doi: 10.1089/hum.2018.258."
COMMENT     Sequence Label: pKAd5f11pABR-EPG
FEATURES             Location/Qualifiers
     source          1..34694
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     repeat_region   42..144
                     /label=ITR
                     /note="inverted terminal repeat of human adenovirus 
                     serotype 5"
     misc_signal     232..382
                     /label=Ad5 Psi
                     /note="packaging signal for adenovirus serotype 5"
     promoter        544..1726
                     /label=EF-1-alpha promoter
                     /note="strong constitutive promoter for human elongation 
                     factor EF-1-alpha"
     intron          775..1717
                     /label=EF-1-alpha intron A
                     /note="intron upstream of the start codon of human 
                     EF-1-alpha"
     primer_bind     1674..1694
                     /label=EF1a-F
                     /note="Human elongation factor-1a promoter, forward primer"
     CDS             join(1742..1744,1745..1747,1748..2458)
                     /codon_start=1
                     /product="enhanced GFP"
                     /label=EGFP
                     /translation="MVSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTL
                     KFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDD
                     GNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIK
                     VNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLL
                     EFVTAAGITLGMDELYK"
     CDS             join(1742..1744,1745..1747,1748..2458)
                     /codon_start=1
                     /product="the original enhanced GFP (Yang et al., 1996)"
                     /label=EGFP
                     /note="mammalian codon-optimized"
                     /translation="MVSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTL
                     KFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDD
                     GNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIK
                     VNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLL
                     EFVTAAGITLGMDELYK"
     primer_bind     complement(1787..1808)
                     /label=EGFP-N
                     /note="EGFP, reverse primer"
     primer_bind     complement(2048..2067)
                     /label=EXFP-R
                     /note="For distinguishing EGFP variants, reverse primer"
     primer_bind     2395..2416
                     /label=EGFP-C
                     /note="EGFP, forward primer"
     polyA_signal    2616..2737
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     primer_bind     complement(2653..2672)
                     /label=SV40pA-R
                     /note="SV40 polyA, reverse primer"
     primer_bind     2707..2726
                     /label=EBV-rev
                     /note="SV40 polyA terminator, reverse primer"
     misc_feature    join(6267..6332,6333..6370)
                     /label=Ad SA
                     /note="adenovirus major late transcript splice acceptor 
                     (Friedrich and Soriano, 1991)"
     CDS             complement(13463..13474)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
     regulatory      20940..20949
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     repeat_region   31642..31744
                     /label=ITR
                     /note="inverted terminal repeat of human adenovirus 
                     serotype 5"
     primer_bind     31785..31804
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
     primer_bind     complement(31885..31902)
                     /label=L4440
                     /note="L4440 vector, forward primer"
     rep_origin      complement(32056..32644)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     complement(32136..32155)
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     CDS             33476..34270
                     /codon_start=1
                     /product="aminoglycoside phosphotransferase"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKASMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     CDS             33476..34270
                     /codon_start=1
                     /gene="aph(3')-II (or nptII)"
                     /product="aminoglycoside phosphotransferase from Tn5"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKASMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     primer_bind     complement(33530..33549)
                     /label=Neo-R
                     /note="Neomycin resistance gene, reverse primer"
     primer_bind     34140..34159
                     /label=Neo-F
                     /note="Neomycin resistance gene, forward primer"
     rep_origin      complement(join(34318..34694,1..4))
                     /direction=LEFT
                     /label=M13 ori
                     /note="M13 bacteriophage origin of replication; arrow 
                     indicates direction of (+) strand synthesis"
     primer_bind     complement(34380..34401)
                     /label=F1ori-F
                     /note="F1 origin, forward primer"
     primer_bind     34592..34611
                     /label=F1ori-R
                     /note="F1 origin, reverse primer"
ORIGIN
        1 gcgtccattc gccattcagg atcgaattaa ttcttaatta acatcatcaa taatatacct
       61 tattttggat tgaagccaat atgataatga gggggtggag tttgtgacgt ggcgcggggc
      121 gtgggaacgg ggcgggtgac gtagtagtgt ggcggaagtg tgatgttgca agtgtggcgg
      181 aacacatgta agcgacggat gtggcaaaag tgacgttttt ggtgtgcgcc ggtgtacaca
      241 ggaagtgaca attttcgcgc ggttttaggc ggatgttgta gtaaatttgg gcgtaaccga
      301 gtaagatttg gccattttcg cgggaaaact gaataagagg aagtgaaatc tgaataattt
      361 tgtgttactc atagcgcgta atactgacgt cgagtaattc atacaaaagg actcgcccct
      421 gccttgggga atcccaggga ccgtcgttaa actcccacta acgtagaacc cagagatcgc
      481 tgcgttcccg ccccctcacc cgcccgctct cgtcatcact gaggtggaga agagcatgcg
      541 tgaggctccg gtgcccgtca gtgggcagag cgcacatcgc ccacagtccc cgagaagttg
      601 gggggagggg tcggcaattg aaccggtgcc tagagaaggt ggcgcggggt aaactgggaa
      661 agtgatgtcg tgtactggct ccgccttttt cccgagggtg ggggagaacc gtatataagt
      721 gcagtagtcg ccgtgaacgt tctttttcgc aacgggtttg ccgccagaac acaggtaagt
      781 gccgtgtgtg gttcccgcgg gcctggcctc tttacgggtt atggcccttg cgtgccttga
      841 attacttcca cgcccctggc tgcagtacgt gattcttgat cccgagcttc gggttggaag
      901 tgggtgggag agttcgaggc cttgcgctta aggagcccct tcgcctcgtg cttgagttga
      961 ggcctggctt gggcgctggg gccgccgcgt gcgaatctgg tggcaccttc gcgcctgtct
     1021 cgctgctttc gataagtctc tagccattta aaatttttga tgacctgctg cgacgctttt
     1081 tttctggcaa gatagtcttg taaatgcggg ccaagatctg cacactggta tttcggtttt
     1141 tggggccgcg ggcggcgacg gggcccgtgc gtcccagcgc acatgttcgg cgaggagggg
     1201 cctgcgagcg cggccaccga gaatcggacg ggggtagtct caagctggcc ggcctgctct
     1261 ggtgcctggc ctcgcgccgc cgtgtatcgc cccgccctgg gcggcaaggc tggcccggtc
     1321 ggcaccagtt gcgtgagcgg aaagatggcc gcttcccggc cctgctgcag ggagctcaaa
     1381 atggaggacg cggcgctcgg gagagcgggc gggtgagtca cccacacaaa ggaaaagggc
     1441 ctttccgtcc tcagccgtcg cttcatgtga ctccacggag taccgggcgc cgtccaggca
     1501 cctcgattag ttctcgagct tttggagtac gtcgtcttta ggttgggggg aggggtttta
     1561 tgcgatggag tttccccaca ctgagtgggt ggagactgaa gttaggccag cttggcactt
     1621 gatgtaattc tccttggaat ttgccctttt tgagtttgga tcttggttca ttctcaagcc
     1681 tcagacagtg gttcaaagtt tttttcttcc atttcaggtg tcgtgaggta ccgtttaaac
     1741 catggtgagc aagggcgagg agctgttcac cggggtggtg cccatcctgg tcgagctgga
     1801 cggcgacgta aacggccaca agttcagcgt gtccggcgag ggcgagggcg atgccaccta
     1861 cggcaagctg accctgaagt tcatctgcac caccggcaag ctgcccgtgc cctggcccac
     1921 cctcgtgacc accctgacct acggcgtgca gtgcttcagc cgctaccccg accacatgaa
     1981 gcagcacgac ttcttcaagt ccgccatgcc cgaaggctac gtccaggagc gcaccatctt
     2041 cttcaaggac gacggcaact acaagacccg cgccgaggtg aagttcgagg gcgacaccct
     2101 ggtgaaccgc atcgagctga agggcatcga cttcaaggag gacggcaaca tcctggggca
     2161 caagctggag tacaactaca acagccacaa cgtctatatc atggccgaca agcagaagaa
     2221 cggcatcaag gtgaacttca agatccgcca caacatcgag gacggcagcg tgcagctcgc
     2281 cgaccactac cagcagaaca cccccatcgg cgacggcccc gtgctgctgc ccgacaacca
     2341 ctacctgagc acccagtccg ccctgagcaa agaccccaac gagaagcgcg atcacatggt
     2401 cctgctggag ttcgtgaccg ccgccgggat cactctcggc atggacgagc tgtacaagtc
     2461 cggactctaa agcttgttta aacatccgat ccaccggatc tagataactg atcataatca
     2521 gccataccac atttgtagag gttttacttg ctttaaaaaa cctcccacac ctccccctga
     2581 acctgaaaca taaaatgaat gcaattgttg ttgttaactt gtttattgca gcttataatg
     2641 gttacaaata aagcaatagc atcacaaatt tcacaaataa agcatttttt tcactgcatt
     2701 ctagttgtgg tttgtccaaa ctcatcaatg tatcttaacg cggatctggg cgtggttaag
     2761 ggtgggaaag aatatataag gtgggggtct tatgtagttt tgtatctgtt ttgcagcagc
     2821 cgccgccgcc atgagcacca actcgtttga tggaagcatt gtgagctcat atttgacaac
     2881 gcgcatgccc ccatgggccg gggtgcgtca gaatgtgatg ggctccagca ttgatggtcg
     2941 ccccgtcctg cccgcaaact ctactacctt gacctacgag accgtgtctg gaacgccgtt
     3001 ggagactgca gcctccgccg ccgcttcagc cgctgcagcc accgcccgcg ggattgtgac
     3061 tgactttgct ttcctgagcc cgcttgcaag cagtgcagct tcccgttcat ccgcccgcga
     3121 tgacaagttg acggctcttt tggcacaatt ggattctttg acccgggaac ttaatgtcgt
     3181 ttctcagcag ctgttggatc tgcgccagca ggtttctgcc ctgaaggctt cctcccctcc
     3241 caatgcggtt taaaacataa ataaaaaacc agactctgtt tggatttgga tcaagcaagt
     3301 gtcttgctgt ctttatttag gggttttgcg cgcgcggtag gcccgggacc agcggtctcg
     3361 gtcgttgagg gtcctgtgta ttttttccag gacgtggtaa aggtgactct ggatgttcag
     3421 atacatgggc ataagcccgt ctctggggtg gaggtagcac cactgcagag cttcatgctg
     3481 cggggtggtg ttgtagatga tccagtcgta gcaggagcgc tgggcgtggt gcctaaaaat
     3541 gtctttcagt agcaagctga ttgccagggg caggcccttg gtgtaagtgt ttacaaagcg
     3601 gttaagctgg gatgggtgca tacgtgggga tatgagatgc atcttggact gtatttttag
     3661 gttggctatg ttcccagcca tatccctccg gggattcatg ttgtgcagaa ccaccagcac
     3721 agtgtatccg gtgcacttgg gaaatttgtc atgtagctta gaaggaaatg cgtggaagaa
     3781 cttggagacg cccttgtgac ctccaagatt ttccatgcat tcgtccataa tgatggcaat
     3841 gggcccacgg gcggcggcct gggcgaagat atttctggga tcactaacgt catagttgtg
     3901 ttccaggatg agatcgtcat aggccatttt tacaaagcgc gggcggaggg tgccagactg
     3961 cggtataatg gttccatccg gcccaggggc gtagttaccc tcacagattt gcatttccca
     4021 cgctttgagt tcagatgggg ggatcatgtc tacctgcggg gcgatgaaga aaacggtttc
     4081 cggggtaggg gagatcagct gggaagaaag caggttcctg agcagctgcg acttaccgca
     4141 gccggtgggc ccgtaaatca cacctattac cggctgcaac tggtagttaa gagagctgca
     4201 gctgccgtca tccctgagca ggggggccac ttcgttaagc atgtccctga ctcgcatgtt
     4261 ttccctgacc aaatccgcca gaaggcgctc gccgcccagc gatagcagtt cttgcaagga
     4321 agcaaagttt ttcaacggtt tgagaccgtc cgccgtaggc atgcttttga gcgtttgacc
     4381 aagcagttcc aggcggtccc acagctcggt cacctgctct acggcatctc gatccagcat
     4441 atctcctcgt ttcgcgggtt ggggcggctt tcgctgtacg gcagtagtcg gtgctcgtcc
     4501 agacgggcca gggtcatgtc tttccacggg cgcagggtcc tcgtcagcgt agtctgggtc
     4561 acggtgaagg ggtgcgctcc gggctgcgcg ctggccaggg tgcgcttgag gctggtcctg
     4621 ctggtgctga agcgctgccg gtcttcgccc tgcgcgtcgg ccaggtagca tttgaccatg
     4681 gtgtcatagt ccagcccctc cgcggcgtgg cccttggcgc gcagcttgcc cttggaggag
     4741 gcgccgcacg aggggcagtg cagacttttg agggcgtaga gcttgggcgc gagaaatacc
     4801 gattccgggg agtaggcatc cgcgccgcag gccccgcaga cggtctcgca ttccacgagc
     4861 caggtgagct ctggccgttc ggggtcaaaa accaggtttc ccccatgctt tttgatgcgt
     4921 ttcttacctc tggtttccat gagccggtgt ccacgctcgg tgacgaaaag gctgtccgtg
     4981 tccccgtata cagacttgag aggcctgtcc tcgagcggtg ttccgcggtc ctcctcgtat
     5041 agaaactcgg accactctga gacaaaggct cgcgtccagg ccagcacgaa ggaggctaag
     5101 tgggaggggt agcggtcgtt gtccactagg gggtccactc gctccagggt gtgaagacac
     5161 atgtcgccct cttcggcatc aaggaaggtg attggtttgt aggtgtaggc cacgtgaccg
     5221 ggtgttcctg aaggggggct ataaaagggg gtgggggcgc gttcgtcctc actctcttcc
     5281 gcatcgctgt ctgcgagggc cagctgttgg ggtgagtact ccctctgaaa agcgggcatg
     5341 acttctgcgc taagattgtc agtttccaaa aacgaggagg atttgatatt cacctggccc
     5401 gcggtgatgc ctttgagggt ggccgcatcc atctggtcag aaaagacaat ctttttgttg
     5461 tcaagcttgg tggcaaacga cccgtagagg gcgttggaca gcaacttggc gatggagcgc
     5521 agggtttggt ttttgtcgcg atcggcgcgc tccttggccg cgatgtttag ctgcacgtat
     5581 tcgcgcgcaa cgcaccgcca ttcgggaaag acggtggtgc gctcgtcggg caccaggtgc
     5641 acgcgccaac cgcggttgtg cagggtgaca aggtcaacgc tggtggctac ctctccgcgt
     5701 aggcgctcgt tggtccagca gaggcggccg cccttgcgcg agcagaatgg cggtaggggg
     5761 tctagctgcg tctcgtccgg ggggtctgcg tccacggtaa agaccccggg cagcaggcgc
     5821 gcgtcgaagt agtctatctt gcatccttgc aagtctagcg cctgctgcca tgcgcgggcg
     5881 gcaagcgcgc gctcgtatgg gttgagtggg ggaccccatg gcatggggtg ggtgagcgcg
     5941 gaggcgtaca tgccgcaaat gtcgtaaacg tagaggggct ctctgagtat tccaagatat
     6001 gtagggtagc atcttccacc gcggatgctg gcgcgcacgt aatcgtatag ttcgtgcgag
     6061 ggagcgagga ggtcgggacc gaggttgcta cgggcgggct gctctgctcg gaagactatc
     6121 tgcctgaaga tggcatgtga gttggatgat atggttggac gctggaagac gttgaagctg
     6181 gcgtctgtga gacctaccgc gtcacgcacg aaggaggcgt aggagtcgcg cagcttgttg
     6241 accagctcgg cggtgacctg cacgtctagg gcgcagtagt ccagggtttc cttgatgatg
     6301 tcatacttat cctgtccctt ttttttccac agctcgcggt tgaggacaaa ctcttcgcgg
     6361 tctttccagt actcttggat cggaaacccg tcggcctccg aacggtaaga gcctagcatg
     6421 tagaactggt tgacggcctg gtaggcgcag catccctttt ctacgggtag cgcgtatgcc
     6481 tgcgcggcct tccggagcga ggtgtgggtg agcgcaaagg tgtccctgac catgactttg
     6541 aggtactggt atttgaagtc agtgtcgtcg catccgccct gctcccagag caaaaagtcc
     6601 gtgcgctttt tggaacgcgg atttggcagg gcgaaggtga catcgttgaa gagtatcttt
     6661 cccgcgcgag gcataaagtt gcgtgtgatg cggaagggtc ccggcacctc ggaacggttg
     6721 ttaattacct gggcggcgag cacgatctcg tcaaagccgt tgatgttgtg gcccacaatg
     6781 taaagttcca agaagcgcgg gatgcccttg atggaaggca attttttaag ttcctcgtag
     6841 gtgagctctt caggggagct gagcccgtgc tctgaaaggg cccagtctgc aagatgaggg
     6901 ttggaagcga cgaatgagct ccacaggtca cgggccatta gcatttgcag gtggtcgcga
     6961 aaggtcctaa actggcgacc tatggccatt ttttctgggg tgatgcagta gaaggtaagc
     7021 gggtcttgtt cccagcggtc ccatccaagg ttcgcggcta ggtctcgcgc ggcagtcact
     7081 agaggctcat ctccgccgaa cttcatgacc agcatgaagg gcacgagctg cttcccaaag
     7141 gcccccatcc aagtataggt ctctacatcg taggtgacaa agagacgctc ggtgcgagga
     7201 tgcgagccga tcgggaagaa ctggatctcc cgccaccaat tggaggagtg gctattgatg
     7261 tggtgaaagt agaagtccct gcgacgggcc gaacactcgt gctggctttt gtaaaaacgt
     7321 gcgcagtact ggcagcggtg cacgggctgt acatcctgca cgaggttgac ctgacgaccg
     7381 cgcacaagga agcagagtgg gaatttgagc ccctcgcctg gcgggtttgg ctggtggtct
     7441 tctacttcgg ctgcttgtcc ttgaccgtct ggctgctcga ggggagttac ggtggatcgg
     7501 accaccacgc cgcgcgagcc caaagtccag atgtccgcgc gcggcggtcg gagcttgatg
     7561 acaacatcgc gcagatggga gctgtccatg gtctggagct cccgcggcgt caggtcaggc
     7621 gggagctcct gcaggtttac ctcgcataga cgggtcaggg cgcgggctag atccaggtga
     7681 tacctaattt ccaggggctg gttggtggcg gcgtcgatgg cttgcaagag gccgcatccc
     7741 cgcggcgcga ctacggtacc gcgcggcggg cggtgggccg cgggggtgtc cttggatgat
     7801 gcatctaaaa gcggtgacgc gggcgagccc ccggaggtag ggggggctcc ggacccgccg
     7861 ggagaggggg caggggcacg tcggcgccgc gcgcgggcag gagctggtgc tgcgcgcgta
     7921 ggttgctggc gaacgcgacg acgcggcggt tgatctcctg aatctggcgc ctctgcgtga
     7981 agacgacggg cccggtgagc ttgaacctga aagagagttc gacagaatca atttcggtgt
     8041 cgttgacggc ggcctggcgc aaaatctcct gcacgtctcc tgagttgtct tgataggcga
     8101 tctcggccat gaactgctcg atctcttcct cctggagatc tccgcgtccg gctcgctcca
     8161 cggtggcggc gaggtcgttg gaaatgcggg ccatgagctg cgagaaggcg ttgaggcctc
     8221 cctcgttcca gacgcggctg tagaccacgc ccccttcggc atcgcgggcg cgcatgacca
     8281 cctgcgcgag attgagctcc acgtgccggg cgaagacggc gtagtttcgc aggcgctgaa
     8341 agaggtagtt gagggtggtg gcggtgtgtt ctgccacgaa gaagtacata acccagcgtc
     8401 gcaacgtgga ttcgttgata tcccccaagg cctcaaggcg ctccatggcc tcgtagaagt
     8461 ccacggcgaa gttgaaaaac tgggagttgc gcgccgacac ggttaactcc tcctccagaa
     8521 gacggatgag ctcggcgaca gtgtcgcgca cctcgcgctc aaaggctaca ggggcctctt
     8581 cttcttcttc aatctcctct tccataaggg cctccccttc ttcttcttct ggcggcggtg
     8641 ggggaggggg gacacggcgg cgacgacggc gcaccgggag gcggtcgaca aagcgctcga
     8701 tcatctcccc gcggcgacgg cgcatggtct cggtgacggc gcggccgttc tcgcgggggc
     8761 gcagttggaa gacgccgccc gtcatgtccc ggttatgggt tggcgggggg ctgccatgcg
     8821 gcagggatac ggcgctaacg atgcatctca acaattgttg tgtaggtact ccgccgccga
     8881 gggacctgag cgagtccgca tcgaccggat cggaaaacct ctcgagaaag gcgtctaacc
     8941 agtcacagtc gcaaggtagg ctgagcaccg tggcgggcgg cagcgggcgg cggtcggggt
     9001 tgtttctggc ggaggtgctg ctgatgatgt aattaaagta ggcggtcttg agacggcgga
     9061 tggtcgacag aagcaccatg tccttgggtc cggcctgctg aatgcgcagg cggtcggcca
     9121 tgccccaggc ttcgttttga catcggcgca ggtctttgta gtagtcttgc atgagccttt
     9181 ctaccggcac ttcttcttct ccttcctctt gtcctgcatc tcttgcatct atcgctgcgg
     9241 cggcggcgga gtttggccgt aggtggcgcc ctcttcctcc catgcgtgtg accccgaagc
     9301 ccctcatcgg ctgaagcagg gctaggtcgg cgacaacgcg ctcggctaat atggcctgct
     9361 gcacctgcgt gagggtagac tggaagtcat ccatgtccac aaagcggtgg tatgcgcccg
     9421 tgttgatggt gtaagtgcag ttggccataa cggaccagtt aacggtctgg tgacccggct
     9481 gcgagagctc ggtgtacctg agacgcgagt aagccctcga gtcaaatacg tagtcgttgc
     9541 aagtccgcac caggtactgg tatcccacca aaaagtgcgg cggcggctgg cggtagaggg
     9601 gccagcgtag ggtggccggg gctccggggg cgagatcttc caacataagg cgatgatatc
     9661 cgtagatgta cctggacatc caggtgatgc cggcggcggt ggtggaggcg cgcggaaagt
     9721 cgcggacgcg gttccagatg ttgcgcagcg gcaaaaagtg ctccatggtc gggacgctct
     9781 ggccggtcag gcgcgcgcaa tcgttgacgc tctagcgtgc aaaaggagag cctgtaagcg
     9841 ggcactcttc cgtggtctgg tggataaatt cgcaagggta tcatggcgga cgaccggggt
     9901 tcgagccccg tatccggccg tccgccgtga tccatgcggt taccgcccgc gtgtcgaacc
     9961 caggtgtgcg acgtcagaca acgggggagt gctccttttg gcttccttcc aggcgcggcg
    10021 gctgctgcgc tagctttttt ggccactggc cgcgcgcagc gtaagcggtt aggctggaaa
    10081 gcgaaagcat taagtggctc gctccctgta gccggagggt tattttccaa gggttgagtc
    10141 gcgggacccc cggttcgagt ctcggaccgg ccggactgcg gcgaacgggg gtttgcctcc
    10201 ccgtcatgca agaccccgct tgcaaattcc tccggaaaca gggacgagcc ccttttttgc
    10261 ttttcccaga tgcatccggt gctgcggcag atgcgccccc ctcctcagca gcggcaagag
    10321 caagagcagc ggcagacatg cagggcaccc tcccctcctc ctaccgcgtc aggaggggcg
    10381 acatccgcgg ttgacgcggc agcagatggt gattacgaac ccccgcggcg ccgggcccgg
    10441 cactacctgg acttggagga gggcgagggc ctggcgcggc taggagcgcc ctctcctgag
    10501 cggcacccaa gggtgcagct gaagcgtgat acgcgtgagg cgtacgtgcc gcggcagaac
    10561 ctgtttcgcg accgcgaggg agaggagccc gaggagatgc gggatcgaaa gttccacgca
    10621 gggcgcgagc tgcggcatgg cctgaatcgc gagcggttgc tgcgcgagga ggactttgag
    10681 cccgacgcgc gaaccgggat tagtcccgcg cgcgcacacg tggcggccgc cgacctggta
    10741 accgcatacg agcagacggt gaaccaggag attaactttc aaaaaagctt taacaaccac
    10801 gtgcgtacgc ttgtggcgcg cgaggaggtg gctataggac tgatgcatct gtgggacttt
    10861 gtaagcgcgc tggagcaaaa cccaaatagc aagccgctca tggcgcagct gttccttata
    10921 gtgcagcaca gcagggacaa cgaggcattc agggatgcgc tgctaaacat agtagagccc
    10981 gagggccgct ggctgctcga tttgataaac atcctgcaga gcatagtggt gcaggagcgc
    11041 agcttgagcc tggctgacaa ggtggccgcc atcaactatt ccatgcttag cctgggcaag
    11101 ttttacgccc gcaagatata ccatacccct tacgttccca tagacaagga ggtaaagatc
    11161 gaggggttct acatgcgcat ggcgctgaag gtgcttacct tgagcgacga cctgggcgtt
    11221 tatcgcaacg agcgcatcca caaggccgtg agcgtgagcc ggcggcgcga gctcagcgac
    11281 cgcgagctga tgcacagcct gcaaagggcc ctggctggca cgggcagcgg cgatagagag
    11341 gccgagtcct actttgacgc gggcgctgac ctgcgctggg ccccaagccg acgcgccctg
    11401 gaggcagctg gggccggacc tgggctggcg gtggcacccg cgcgcgctgg caacgtcggc
    11461 ggcgtggagg aatatgacga ggacgatgag tacgagccag aggacggcga gtactaagcg
    11521 gtgatgtttc tgatcagatg atgcaagacg caacggaccc ggcggtgcgg gcggcgctgc
    11581 agagccagcc gtccggcctt aactccacgg acgactggcg ccaggtcatg gaccgcatca
    11641 tgtcgctgac tgcgcgcaat cctgacgcgt tccggcagca gccgcaggcc aaccggctct
    11701 ccgcaattct ggaagcggtg gtcccggcgc gcgcaaaccc cacgcacgag aaggtgctgg
    11761 cgatcgtaaa cgcgctggcc gaaaacaggg ccatccggcc cgacgaggcc ggcctggtct
    11821 acgacgcgct gcttcagcgc gtggctcgtt acaacagcgg caacgtgcag accaacctgg
    11881 accggctggt gggggatgtg cgcgaggccg tggcgcagcg tgagcgcgcg cagcagcagg
    11941 gcaacctggg ctccatggtt gcactaaacg ccttcctgag tacacagccc gccaacgtgc
    12001 cgcggggaca ggaggactac accaactttg tgagcgcact gcggctaatg gtgactgaga
    12061 caccgcaaag tgaggtgtac cagtctgggc cagactattt tttccagacc agtagacaag
    12121 gcctgcagac cgtaaacctg agccaggctt tcaaaaactt gcaggggctg tggggggtgc
    12181 gggctcccac aggcgaccgc gcgaccgtgt ctagcttgct gacgcccaac tcgcgcctgt
    12241 tgctgctgct aatagcgccc ttcacggaca gtggcagcgt gtcccgggac acatacctag
    12301 gtcacttgct gacactgtac cgcgaggcca taggtcaggc gcatgtggac gagcatactt
    12361 tccaggagat tacaagtgtc agccgcgcgc tggggcagga ggacacgggc agcctggagg
    12421 caaccctaaa ctacctgctg accaaccggc ggcagaagat cccctcgttg cacagtttaa
    12481 atagcgagga ggagcgcatt ttgcgctacg tgcagcagag cgtgagcctt aacctgatgc
    12541 gcgacggggt aacgcccagc gtggcgctgg acatgaccgc gcgcaacatg gaaccgggca
    12601 tgtatgcctc aaaccggccg tttatcaacc gcctaatgga ctacttgcat cgcgcggccg
    12661 ccgtgaaccc cgagtatttc accaatgcca tcttgaaccc gcactggcta ccgccccctg
    12721 gtttctacac cgggggattc gaggtgcccg agggtaacga tggattcctc tgggacgaca
    12781 tagacgacag cgtgttttcc ccgcaaccgc agaccctgct agagttgcaa cagcgcgagc
    12841 aggcagaggc ggcgctgcga aaggaaagct tccgcaggcc aagcagcttg tccgatctag
    12901 gcgctgcggc cccgcggtca gatgctagta gcccatttcc aagcttgata gggtctctta
    12961 ccagcactcg caccacccgc ccgcgcctgc tgggcgagga ggagtaccta aacaactcgc
    13021 tgctgcagcc gcagcgcgaa aaaaacctgc ctccggcatt tcccaacaac gggatagaga
    13081 gcctagtgga caagatgagt agatggaaga cgtacgcgca ggagcacagg gacgtgccag
    13141 gcccgcgccc gcccacccgt cgtcaaaggc acgaccgtca gcggggtctg gtgtgggagg
    13201 acgatgactc ggcagacgac agcagcgtcc tggatttggg agggagtggc aacccgtttg
    13261 cgcaccttcg ccccaggctg gggagaatgt tttaaaaaaa aaaaagcatg atgcaaaata
    13321 aaaaactcac caaggccatg gcaccgagcg ttggttttct tgtattcccc ttagtatgcg
    13381 gcgcgcggcg atgtatgagg aaggtcctcc tccctcctac gagagtgtgg tgagcgcggc
    13441 gccagtggcg gcggcgctgg gttctccctt cgatgctccc ctggacccgc cgtttgtgcc
    13501 tccgcggtac ctgcggccta ccggggggag aaacagcatc cgttactctg agttggcacc
    13561 cctattcgac accacccgtg tgtacctggt ggacaacaag tcaacggatg tggcatccct
    13621 gaactaccag aacgaccaca gcaactttct gaccacggtc attcaaaaca atgactacag
    13681 cccgggggag gcaagcacac agaccatcaa tcttgacgac cggtcgcact ggggcggcga
    13741 cctgaaaacc atcctgcata ccaacatgcc aaatgtgaac gagttcatgt ttaccaataa
    13801 gtttaaggcg cgggtgatgg tgtcgcgctt gcctactaag gacaatcagg tggagctgaa
    13861 atacgagtgg gtggagttca cgctgcccga gggcaactac tccgagacca tgaccataga
    13921 ccttatgaac aacgcgatcg tggagcacta cttgaaagtg ggcagacaga acggggttct
    13981 ggaaagcgac atcggggtaa agtttgacac ccgcaacttc agactggggt ttgaccccgt
    14041 cactggtctt gtcatgcctg gggtatatac aaacgaagcc ttccatccag acatcatttt
    14101 gctgccagga tgcggggtgg acttcaccca cagccgcctg agcaacttgt tgggcatccg
    14161 caagcggcaa cccttccagg agggctttag gatcacctac gatgatctgg agggtggtaa
    14221 cattcccgca ctgttggatg tggacgccta ccaggcgagc ttgaaagatg acaccgaaca
    14281 gggcgggggt ggcgcaggcg gcagcaacag cagtggcagc ggcgcggaag agaactccaa
    14341 cgcggcagcc gcggcaatgc agccggtgga ggacatgaac gatcatgcca ttcgcggcga
    14401 cacctttgcc acacgggctg aggagaagcg cgctgaggcc gaagcagcgg ccgaagctgc
    14461 cgcccccgct gcgcaacccg aggtcgagaa gcctcagaag aaaccggtga tcaaacccct
    14521 gacagaggac agcaagaaac gcagttacaa cctaataagc aatgacagca ccttcaccca
    14581 gtaccgcagc tggtaccttg catacaacta cggcgaccct cagaccggaa tccgctcatg
    14641 gaccctgctt tgcactcctg acgtaacctg cggctcggag caggtctact ggtcgttgcc
    14701 agacatgatg caagaccccg tgaccttccg ctccacgcgc cagatcagca actttccggt
    14761 ggtgggcgcc gagctgttgc ccgtgcactc caagagcttc tacaacgacc aggccgtcta
    14821 ctcccaactc atccgccagt ttacctctct gacccacgtg ttcaatcgct ttcccgagaa
    14881 ccagattttg gcgcgcccgc cagcccccac catcaccacc gtcagtgaaa acgttcctgc
    14941 tctcacagat cacgggacgc taccgctgcg caacagcatc ggaggagtcc agcgagtgac
    15001 cattactgac gccagacgcc gcacctgccc ctacgtttac aaggccctgg gcatagtctc
    15061 gccgcgcgtc ctatcgagcc gcactttttg agcaagcatg tccatcctta tatcgcccag
    15121 caataacaca ggctggggcc tgcgcttccc aagcaagatg tttggcgggg ccaagaagcg
    15181 ctccgaccaa cacccagtgc gcgtgcgcgg gcactaccgc gcgccctggg gcgcgcacaa
    15241 acgcggccgc actgggcgca ccaccgtcga tgacgccatc gacgcggtgg tggaggaggc
    15301 gcgcaactac acgcccacgc cgccaccagt gtccacagtg gacgcggcca ttcagaccgt
    15361 ggtgcgcgga gcccggcgct atgctaaaat gaagagacgg cggaggcgcg tagcacgtcg
    15421 ccaccgccgc cgacccggca ctgccgccca acgcgcggcg gcggccctgc ttaaccgcgc
    15481 acgtcgcacc ggccgacggg cggccatgcg ggccgctcga aggctggccg cgggtattgt
    15541 cactgtgccc cccaggtcca ggcgacgagc ggccgccgca gcagccgcgg ccattagtgc
    15601 tatgactcag ggtcgcaggg gcaacgtgta ttgggtgcgc gactcggtta gcggcctgcg
    15661 cgtgcccgtg cgcacccgcc ccccgcgcaa ctagattgca agaaaaaact acttagactc
    15721 gtactgttgt atgtatccag cggcggcggc gcgcaacgaa gctatgtcca agcgcaaaat
    15781 caaagaagag atgctccagg tcatcgcgcc ggagatctat ggccccccga agaaggaaga
    15841 gcaggattac aagccccgaa agctaaagcg ggtcaaaaag aaaaagaaag atgatgatga
    15901 tgaacttgac gacgaggtgg aactgctgca cgctaccgcg cccaggcgac gggtacagtg
    15961 gaaaggtcga cgcgtaaaac gtgttttgcg acccggcacc accgtagtct ttacgcccgg
    16021 tgagcgctcc acccgcacct acaagcgcgt gtatgatgag gtgtacggcg acgaggacct
    16081 gcttgagcag gccaacgagc gcctcgggga gtttgcctac ggaaagcggc ataaggacat
    16141 gctggcgttg ccgctggacg agggcaaccc aacacctagc ctaaagcccg taacactgca
    16201 gcaggtgctg cccgcgcttg caccgtccga agaaaagcgc ggcctaaagc gcgagtctgg
    16261 tgacttggca cccaccgtgc agctgatggt acccaagcgc cagcgactgg aagatgtctt
    16321 ggaaaaaatg accgtggaac ctgggctgga gcccgaggtc cgcgtgcggc caatcaagca
    16381 ggtggcgccg ggactgggcg tgcagaccgt ggacgttcag atacccacta ccagtagcac
    16441 cagtattgcc accgccacag agggcatgga gacacaaacg tccccggttg cctcagcggt
    16501 ggcggatgcc gcggtgcagg cggtcgctgc ggccgcgtcc aagacctcta cggaggtgca
    16561 aacggacccg tggatgtttc gcgtttcagc cccccggcgc ccgcgccgtt cgaggaagta
    16621 cggcgccgcc agcgcgctac tgcccgaata tgccctacat ccttccattg cgcctacccc
    16681 cggctatcgt ggctacacct accgccccag aagacgagca actacccgac gccgaaccac
    16741 cactggaacc cgccgccgcc gtcgccagcc cgtgctggcc ccgatttccg tgcgcagggt
    16801 ggctcgcgaa ggaggcagga ccctggtgct gccaacagcg cgctaccacc ccagcatcgt
    16861 ttaaaagccg gtctttgtgg ttcttgcaga tatggccctc acctgccgcc tccgtttccc
    16921 ggtgccggga ttccgaggaa gaatgcaccg taggaggggc atggccggcc acggcctgac
    16981 gggcggcatg cgtcgtgcgc accaccggcg gcggcgcgcg tcgcaccgtc gcatgcgcgg
    17041 cggtatcctg cccctcctta ttccactgat cgccgcggcg attggcgccg tgcccggaat
    17101 tgcatccgtg gccttgcagg cgcagagaca ctgattaaaa acaagttgca tgtggaaaaa
    17161 tcaaaataaa aagtctggac tctcacgctc gcttggtcct gtaactattt tgtagaatgg
    17221 aagacatcaa ctttgcgtct ctggccccgc gacacggctc gcgcccgttc atgggaaact
    17281 ggcaagatat cggcaccagc aatatgagcg gtggcgcctt cagctggggc tcgctgtgga
    17341 gcggcattaa aaatttcggt tccaccgtta agaactatgg cagcaaggcc tggaacagca
    17401 gcacaggcca gatgctgagg gataagttga aagagcaaaa tttccaacaa aaggtggtag
    17461 atggcctggc ctctggcatt agcggggtgg tggacctggc caaccaggca gtgcaaaata
    17521 agattaacag taagcttgat ccccgccctc ccgtagagga gcctccaccg gccgtggaga
    17581 cagtgtctcc agaggggcgt ggcgaaaagc gtccgcgccc cgacagggaa gaaactctgg
    17641 tgacgcaaat agacgagcct ccctcgtacg aggaggcact aaagcaaggc ctgcccacca
    17701 cccgtcccat cgcgcccatg gctaccggag tgctgggcca gcacacaccc gtaacgctgg
    17761 acctgcctcc ccccgccgac acccagcaga aacctgtgct gccaggcccg accgccgttg
    17821 ttgtaacccg tcctagccgc gcgtccctgc gccgcgccgc cagcggtccg cgatcgttgc
    17881 ggcccgtagc cagtggcaac tggcaaagca cactgaacag catcgtgggt ctgggggtgc
    17941 aatccctgaa gcgccgacga tgcttctgat agctaacgtg tcgtatgtgt gtcatgtatg
    18001 cgtccatgtc gccgccagag gagctgctga gccgccgcgc gcccgctttc caagatggct
    18061 accccttcga tgatgccgca gtggtcttac atgcacatct cgggccagga cgcctcggag
    18121 tacctgagcc ccgggctggt gcagtttgcc cgcgccaccg agacgtactt cagcctgaat
    18181 aacaagttta gaaaccccac ggtggcgcct acgcacgacg tgaccacaga ccggtcccag
    18241 cgtttgacgc tgcggttcat ccctgtggac cgtgaggata ctgcgtactc gtacaaggcg
    18301 cggttcaccc tagctgtggg tgataaccgt gtgctggaca tggcttccac gtactttgac
    18361 atccgcggcg tgctggacag gggccctact tttaagccct actctggcac tgcctacaac
    18421 gccctggctc ccaagggtgc cccaaatcct tgcgaatggg atgaagctgc tactgctctt
    18481 gaaataaacc tagaagaaga ggacgatgac aacgaagacg aagtagacga gcaagctgag
    18541 cagcaaaaaa ctcacgtatt tgggcaggcg ccttattctg gtataaatat tacaaaggag
    18601 ggtattcaaa taggtgtcga aggtcaaaca cctaaatatg ccgataaaac atttcaacct
    18661 gaacctcaaa taggagaatc tcagtggtac gaaacagaaa ttaatcatgc agctgggaga
    18721 gtcctaaaaa agactacccc aatgaaacca tgttacggtt catatgcaaa acccacaaat
    18781 gaaaatggag ggcaaggcat tcttgtaaag caacaaaatg gaaagctaga aagtcaagtg
    18841 gaaatgcaat ttttctcaac tactgaggca gccgcaggca atggtgataa cttgactcct
    18901 aaagtggtat tgtacagtga agatgtagat atagaaaccc cagacactca tatttcttac
    18961 atgcccacta ttaaggaagg taactcacga gaactaatgg gccaacaatc tatgcccaac
    19021 aggcctaatt acattgcttt tagggacaat tttattggtc taatgtatta caacagcacg
    19081 ggtaatatgg gtgttctggc gggccaagca tcgcagttga atgctgttgt agatttgcaa
    19141 gacagaaaca cagagctttc ataccagctt ttgcttgatt ccattggtga tagaaccagg
    19201 tacttttcta tgtggaatca ggctgttgac agctatgatc cagatgttag aattattgaa
    19261 aatcatggaa ctgaagatga acttccaaat tactgctttc cactgggagg tgtgattaat
    19321 acagagactc ttaccaaggt aaaacctaaa acaggtcagg aaaatggatg ggaaaaagat
    19381 gctacagaat tttcagataa aaatgaaata agagttggaa ataattttgc catggaaatc
    19441 aatctaaatg ccaacctgtg gagaaatttc ctgtactcca acatagcgct gtatttgccc
    19501 gacaagctaa agtacagtcc ttccaacgta aaaatttctg ataacccaaa cacctacgac
    19561 tacatgaaca agcgagtggt ggctcccggg ctagtggact gctacattaa ccttggagca
    19621 cgctggtccc ttgactatat ggacaacgtc aacccattta accaccaccg caatgctggc
    19681 ctgcgctacc gctcaatgtt gctgggcaat ggtcgctatg tgcccttcca catccaggtg
    19741 cctcagaagt tctttgccat taaaaacctc cttctcctgc cgggctcata cacctacgag
    19801 tggaacttca ggaaggatgt taacatggtt ctgcagagct ccctaggaaa tgacctaagg
    19861 gttgacggag ccagcattaa gtttgatagc atttgccttt acgccacctt cttccccatg
    19921 gcccacaaca ccgcctccac gcttgaggcc atgcttagaa acgacaccaa cgaccagtcc
    19981 tttaacgact atctctccgc cgccaacatg ctctacccta tacccgccaa cgctaccaac
    20041 gtgcccatat ccatcccctc ccgcaactgg gcggctttcc gcggctgggc cttcacgcgc
    20101 cttaagacta aggaaacccc atcactgggc tcgggctacg acccttatta cacctactct
    20161 ggctctatac cctacctaga tggaaccttt tacctcaacc acacctttaa gaaggtggcc
    20221 attacctttg actcttctgt cagctggcct ggcaatgacc gcctgcttac ccccaacgag
    20281 tttgaaatta agcgctcagt tgacggggag ggttacaacg ttgcccagtg taacatgacc
    20341 aaagactggt tcctggtaca aatgctagct aactataaca ttggctacca gggcttctat
    20401 atcccagaga gctacaagga ccgcatgtac tccttcttta gaaacttcca gcccatgagc
    20461 cgtcaggtgg tggatgatac taaatacaag gactaccaac aggtgggcat cctacaccaa
    20521 cacaacaact ctggatttgt tggctacctt gcccccacca tgcgcgaagg acaggcctac
    20581 cctgctaact tcccctatcc gcttataggc aagaccgcag ttgacagcat tacccagaaa
    20641 aagtttcttt gcgatcgcac cctttggcgc atcccattct ccagtaactt tatgtccatg
    20701 ggcgcactca cagacctggg ccaaaacctt ctctacgcca actccgccca cgcgctagac
    20761 atgacttttg aggtggatcc catggacgag cccacccttc tttatgtttt gtttgaagtc
    20821 tttgacgtgg tccgtgtgca ccagccgcac cgcggcgtca tcgaaaccgt gtacctgcgc
    20881 acgcccttct cggccggcaa cgccacaaca taaagaagca agcaacatca acaacagctg
    20941 ccgccatggg ctccagtgag caggaactga aagccattgt caaagatctt ggttgtgggc
    21001 catatttttt gggcacctat gacaagcgct ttccaggctt tgtttctcca cacaagctcg
    21061 cctgcgccat agtcaatacg gccggtcgcg agactggggg cgtacactgg atggcctttg
    21121 cctggaaccc gcactcaaaa acatgctacc tctttgagcc ctttggcttt tctgaccagc
    21181 gactcaagca ggtttaccag tttgagtacg agtcactcct gcgccgtagc gccattgctt
    21241 cttcccccga ccgctgtata acgctggaaa agtccaccca aagcgtacag gggcccaact
    21301 cggccgcctg tggactattc tgctgcatgt ttctccacgc ctttgccaac tggccccaaa
    21361 ctcccatgga tcacaacccc accatgaacc ttattaccgg ggtacccaac tccatgctca
    21421 acagtcccca ggtacagccc accctgcgtc gcaaccagga acagctctac agcttcctgg
    21481 agcgccactc gccctacttc cgcagccaca gtgcgcagat taggagcgcc acttcttttt
    21541 gtcacttgaa aaacatgtaa aaataatgta ctagagacac tttcaataaa ggcaaatgct
    21601 tttatttgta cactctcggg tgattattta cccccaccct tgccgtctgc gccgtttaaa
    21661 aatcaaaggg gttctgccgc gcatcgctat gcgccactgg cagggacacg ttgcgatact
    21721 ggtgtttagt gctccactta aactcaggca caaccatccg cggcagctcg gtgaagtttt
    21781 cactccacag gctgcgcacc atcaccaacg cgtttagcag gtcgggcgcc gatatcttga
    21841 agtcgcagtt ggggcctccg ccctgcgcgc gcgagttgcg atacacaggg ttgcagcact
    21901 ggaacactat cagcgccggg tggtgcacgc tggccagcac gctcttgtcg gagatcagat
    21961 ccgcgtccag gtcctccgcg ttgctcaggg cgaacggagt caactttggt agctgccttc
    22021 ccaaaaaggg cgcgtgccca ggctttgagt tgcactcgca ccgtagtggc atcaaaaggt
    22081 gaccgtgccc ggtctgggcg ttaggataca gcgcctgcat aaaagccttg atctgcttaa
    22141 aagccacctg agcctttgcg ccttcagaga agaacatgcc gcaagacttg ccggaaaact
    22201 gattggccgg acaggccgcg tcgtgcacgc agcaccttgc gtcggtgttg gagatctgca
    22261 ccacatttcg gccccaccgg ttcttcacga tcttggcctt gctagactgc tccttcagcg
    22321 cgcgctgccc gttttcgctc gtcacatcca tttcaatcac gtgctcctta tttatcataa
    22381 tgcttccgtg tagacactta agctcgcctt cgatctcagc gcagcggtgc agccacaacg
    22441 cgcagcccgt gggctcgtga tgcttgtagg tcacctctgc aaacgactgc aggtacgcct
    22501 gcaggaatcg ccccatcatc gtcacaaagg tcttgttgct ggtgaaggtc agctgcaacc
    22561 cgcggtgctc ctcgttcagc caggtcttgc atacggccgc cagagcttcc acttggtcag
    22621 gcagtagttt gaagttcgcc tttagatcgt tatccacgtg gtacttgtcc atcagcgcgc
    22681 gcgcagcctc catgcccttc tcccacgcag acacgatcgg cacactcagc gggttcatca
    22741 ccgtaatttc actttccgct tcgctgggct cttcctcttc ctcttgcgtc cgcataccac
    22801 gcgccactgg gtcgtcttca ttcagccgcc gcactgtgcg cttacctcct ttgccatgct
    22861 tgattagcac cggtgggttg ctgaaaccca ccatttgtag cgccacatct tctctttctt
    22921 cctcgctgtc cacgattacc tctggtgatg gcgggcgctc gggcttggga gaagggcgct
    22981 tctttttctt cttgggcgca atggccaaat ccgccgccga ggtcgatggc cgcgggctgg
    23041 gtgtgcgcgg caccagcgcg tcttgtgatg agtcttcctc gtcctcggac tcgatacgcc
    23101 gcctcatccg cttttttggg ggcgcccggg gaggcggcgg cgacggggac ggggacgaca
    23161 cgtcctccat ggttggggga cgtcgcgccg caccgcgtcc gcgctcgggg gtggtttcgc
    23221 gctgctcctc ttcccgactg gccatttcct tctcctatag gcagaaaaag atcatggagt
    23281 cagtcgagaa gaaggacagc ctaaccgccc cctctgagtt cgccaccacc gcctccaccg
    23341 atgccgccaa cgcgcctacc accttccccg tcgaggcacc cccgcttgag gaggaggaag
    23401 tgattatcga gcaggaccca ggttttgtaa gcgaagacga cgaggaccgc tcagtaccaa
    23461 cagaggataa aaagcaagac caggacaacg cagaggcaaa cgaggaacaa gtcgggcggg
    23521 gggacgaaag gcatggcgac tacctagatg tgggagacga cgtgctgttg aagcatctgc
    23581 agcgccagtg cgccattatc tgcgacgcgt tgcaagagcg cagcgatgtg cccctcgcca
    23641 tagcggatgt cagccttgcc tacgaacgcc acctattctc accgcgcgta ccccccaaac
    23701 gccaagaaaa cggcacatgc gagcccaacc cgcgcctcaa cttctacccc gtatttgccg
    23761 tgccagaggt gcttgccacc tatcacatct ttttccaaaa ctgcaagata cccctatcct
    23821 gccgtgccaa ccgcagccga gcggacaagc agctggcctt gcggcagggc gctgtcatac
    23881 ctgatatcgc ctcgctcaac gaagtgccaa aaatctttga gggtcttgga cgcgacgaga
    23941 agcgcgcggc aaacgctctg caacaggaaa acagcgaaaa tgaaagtcac tctggagtgt
    24001 tggtggaact cgagggtgac aacgcgcgcc tagccgtact aaaacgcagc atcgaggtca
    24061 cccactttgc ctacccggca cttaacctac cccccaaggt catgagcaca gtcatgagtg
    24121 agctgatcgt gcgccgtgcg cagcccctgg agagggatgc aaatttgcaa gaacaaacag
    24181 aggagggcct acccgcagtt ggcgacgagc agctagcgcg ctggcttcaa acgcgcgagc
    24241 ctgccgactt ggaggagcga cgcaaactaa tgatggccgc agtgctcgtt accgtggagc
    24301 ttgagtgcat gcagcggttc tttgctgacc cggagatgca gcgcaagcta gaggaaacat
    24361 tgcactacac ctttcgacag ggctacgtac gccaggcctg caagatctcc aacgtggagc
    24421 tctgcaacct ggtctcctac cttggaattt tgcacgaaaa ccgccttggg caaaacgtgc
    24481 ttcattccac gctcaagggc gaggcgcgcc gcgactacgt ccgcgactgc gtttacttat
    24541 ttctatgcta cacctggcag acggccatgg gcgtttggca gcagtgcttg gaggagtgca
    24601 acctcaagga gctgcagaaa ctgctaaagc aaaacttgaa ggacctatgg acggccttca
    24661 acgagcgctc cgtggccgcg cacctggcgg acatcatttt ccccgaacgc ctgcttaaaa
    24721 ccctgcaaca gggtctgcca gacttcacca gtcaaagcat gttgcagaac tttaggaact
    24781 ttatcctaga gcgctcagga atcttgcccg ccacctgctg tgcacttcct agcgactttg
    24841 tgcccattaa gtaccgcgaa tgccctccgc cgctttgggg ccactgctac cttctgcagc
    24901 tagccaacta ccttgcctac cactctgaca taatggaaga cgtgagcggt gacggtctac
    24961 tggagtgtca ctgtcgctgc aacctatgca ccccgcaccg ctccctggtt tgcaattcgc
    25021 agctgcttaa cgaaagtcaa attatcggta cctttgagct gcagggtccc tcgcctgacg
    25081 aaaagtccgc ggctccgggg ttgaaactca ctccggggct gtggacgtcg gcttaccttc
    25141 gcaaatttgt acctgaggac taccacgccc acgagattag gttctacgaa gaccaatccc
    25201 gcccgcctaa tgcggagctt accgcctgcg tcattaccca gggccacatt cttggccaat
    25261 tgcaagccat caacaaagcc cgccaagagt ttctgctacg aaagggacgg ggggtttact
    25321 tggaccccca gtccggcgag gagctcaacc caatcccccc gccgccgcag ccctatcagc
    25381 agcagccgcg ggcccttgct tcccaggatg gcacccaaaa agaagctgca gctgccgccg
    25441 ccacccacgg acgaggagga atactgggac agtcaggcag aggaggtttt ggacgaggag
    25501 gaggaggaca tgatggaaga ctgggagagc ctagacgagg aagcttccga ggtcgaagag
    25561 gtgtcagacg aaacaccgtc accctcggtc gcattcccct cgccggcgcc ccagaaatcg
    25621 gcaaccggtt ccagcatggc tacaacctcc gctcctcagg cgccgccggc actgcccgtt
    25681 cgccgaccca accgtagatg ggacaccact ggaaccaggg ccggtaagtc caagcagccg
    25741 ccgccgttag cccaagagca acaacagcgc caaggctacc gctcatggcg cgggcacaag
    25801 aacgccatag ttgcttgctt gcaagactgt gggggcaaca tctccttcgc ccgccgcttt
    25861 cttctctacc atcacggcgt ggccttcccc cgtaacatcc tgcattacta ccgtcatctc
    25921 tacagcccat actgcaccgg cggcagcggc agcaacagca gcggccacac agaagcaaag
    25981 gcgaccggat agcaagactc tgacaaagcc caagaaatcc acagcggcgg cagcagcagg
    26041 aggaggagcg ctgcgtctgg cgcccaacga acccgtatcg acccgcgagc ttagaaacag
    26101 gatttttccc actctgtatg ctatatttca acagagcagg ggccaagaac aagagctgaa
    26161 aataaaaaac aggtctctgc gatccctcac ccgcagctgc ctgtatcaca aaagcgaaga
    26221 tcagcttcgg cgcacgctgg aagacgcgga ggctctcttc agtaaatact gcgcgctgac
    26281 tcttaaggac tagtttcgcg ccctttctca aatttaagcg cgaaaactac gtcatctcca
    26341 gcggccacac ccggcgccag cacctgttgt cagcgccatt atgagcaagg aaattcccac
    26401 gccctacatg tggagttacc agccacaaat gggacttgcg gctggagctg cccaagacta
    26461 ctcaacccga ataaactaca tgagcgcggg accccacatg atatcccggg tcaacggaat
    26521 acgcgcccac cgaaaccgaa ttctcctgga acaggcggct attaccacca cacctcgtaa
    26581 taaccttaat ccccgtagtt ggcccgctgc cctggtgtac caggaaagtc ccgctcccac
    26641 cactgtggta cttcccagag acgcccaggc cgaagttcag atgactaact caggggcgca
    26701 gcttgcgggc ggctttcgtc acagggtgcg gtcgcccggg cagggtataa ctcacctgac
    26761 aatcagaggg cgaggtattc agctcaacga cgagtcggtg agctcctcgc ttggtctccg
    26821 tccggacggg acatttcaga tcggcggcgc cggccgctct tcattcacgc ctcgtcaggc
    26881 aatcctaact ctgcagacct cgtcctctga gccgcgctct ggaggcattg gaactctgca
    26941 atttattgag gagtttgtgc catcggtcta ctttaacccc ttctcgggac ctcccggcca
    27001 ctatccggat caatttattc ctaactttga cgcggtaaag gactcggcgg acggctacga
    27061 ctgaatgtta agtggagagg cagagcaact gcgcctgaaa cacctggtcc actgtcgccg
    27121 ccacaagtgc tttgcccgcg actccggtga gttttgctac tttgaattgc ccgaggatca
    27181 tatcgagggc ccggcgcacg gcgtccggct taccgcccag ggagagcttg cccgtagcct
    27241 gattcgggag tttacccagc gccccctgct agttgagcgg gacaggggac cctgtgttct
    27301 cactgtgatt tgcaactgtc ctaaccctgg attacatcaa gatcctctag ttatcgattc
    27361 cctttaacta ataaaaaaaa ataataaagc atcacttact taaaatcagt tagcaaattt
    27421 ctgtccagtt tattcagcag cacctccttg ccctcctccc agctctggta ttgcagcttc
    27481 ctcctggctg caaactttct ccacaatcta aatggaatgt cagtttcctc ctgttcctgt
    27541 ccatccgcac ccactatctt catgttgttg cagatgaagc gcgcaagacc gtctgaagat
    27601 accttcaacc ccgtgtatcc atatgacacg gaaaccggtc ctccaactgt gccttttctt
    27661 actcctccct ttgtatcccc caatgggttt caagagagtc cccctggagt tcttacttta
    27721 aaatgtttaa ccccactaac aaccacaggc ggatctctac agctaaaagt gggaggggga
    27781 cttacagtgg atgacaccaa cggttttttg aaagaaaaca taagtgccac cacaccactc
    27841 gttaagactg gtcactctat aggtttacca ctaggagccg gattgggaac gaatgaaaat
    27901 aaactttgta tcaaattagg acaaggactt acattcaatt caaacaacat ttgcattgat
    27961 gacaatatta acaccttatg gacaggagtc aaccccaccg aagccaactg tcaaatcatg
    28021 aactccagtg aatgtgactg ccgcggagac tgtttctgct ctaatgattg caaattaatt
    28081 ctaacactag ttaaaactgg agcactagtc actgcatttg tttatgttat aggagtatct
    28141 aacaatttta atatgctaac tacacacaga aatataaatt ttactgcaga gctgtttttc
    28201 gattctactg gtaatttact aactagactc tcatccctca aaactccact taatcataaa
    28261 tcaggacaaa acatggctac tggtgccatt actaatgcta aaggtttcat gcccagcacg
    28321 actgcctatc ctttcaatga taattctaga gaaaaagaaa actacattta cggaacttgt
    28381 tactacacag ctagtgatcg cactgctttt cccattgaca tatctgtcat gcttaaccga
    28441 agagcaataa atgacgagac atcatattgt attcgtataa cttggtcctg gaacacagga
    28501 gatgccccag aggtgcaaac ctctgctaca accctagtca cctccccatt taccttttac
    28561 tacatcagag aagacgactg agcccaagaa taaagaatcg attgtgttat gtttcaacgt
    28621 gtttattttt caattgcaga aaatttcaag tcatttttca ttcagtagta tagccccacc
    28681 accacatagc ttatacagat caccgtacct taatcaaact cacagaaccc tagtattcaa
    28741 cctgccacct ccctcccaac acacagagta cacagtcctt tctccccggc tggccttaaa
    28801 aagcatcata tcatgggtaa cagacatatt cttaggtgtt atattccaca cggtttcctg
    28861 tcgagccaaa cgctcatcag tgatattaat aaactccccg ggcagctcac ttaagttcat
    28921 gtcgctgtcc agctgctgag ccacaggctg ctgtccaact tgcggttgct taacgggcgg
    28981 cgaaggagaa gtccacgcct acatgggggt agagtcataa tcgtgcatca ggatagggcg
    29041 gtggtgctgc agcagcgcgc gaataaactg ctgccgccgc cgctccgtcc tgcaggaata
    29101 caacatggca gtggtctcct cagcgatgat tcgcaccgcc cgcagcataa ggcgccttgt
    29161 cctccgggca cagcagcgca ccctgatctc acttaaatca gcacagtaac tgcagcacag
    29221 caccacaata ttgttcaaaa tcccacagtg caaggcgctg tatccaaagc tcatggcggg
    29281 gaccacagaa cccacgtggc catcatacca caagcgcagg tagattaagt ggcgacccct
    29341 cataaacacg ctggacataa acattacctc ttttggcatg ttgtaattca ccacctcccg
    29401 gtaccatata aacctctgat taaacatggc gccatccacc accatcctaa accagctggc
    29461 caaaacctgc ccgccggcta tacactgcag ggaaccggga ctggaacaat gacagtggag
    29521 agcccaggac tcgtaaccat ggatcatcat gctcgtcatg atatcaatgt tggcacaaca
    29581 caggcacacg tgcatacact tcctcaggat tacaagctcc tcccgcgtta gaaccatatc
    29641 ccagggaaca acccattcct gaatcagcgt aaatcccaca ctgcagggaa gacctcgcac
    29701 gtaactcacg ttgtgcattg tcaaagtgtt acattcgggc agcagcggat gatcctccag
    29761 tatggtagcg cgggtttctg tctcaaaagg aggtagacga tccctactgt acggagtgcg
    29821 ccgagacaac cgagatcgtg ttggtcgtag tgtcatgcca aatggaacgc cggacgtagt
    29881 catatttcct gaagcaaaac caggtgcggg cgtgacaaac agatctgcgt ctccggtctc
    29941 gccgcttaga tcgctctgtg tagtagttgt agtatatcca ctctctcaaa gcatccaggc
    30001 gccccctggc ttcgggttct atgtaaactc cttcatgcgc cgctgccctg ataacatcca
    30061 ccaccgcaga ataagccaca cccagccaac ctacacattc gttctgcgag tcacacacgg
    30121 gaggagcggg aagagctgga agaaccatgt tttttttttt attccaaaag attatccaaa
    30181 acctcaaaat gaagatctat taagtgaacg cgctcccctc cggtggcgtg gtcaaactct
    30241 acagccaaag aacagataat ggcatttgta agatgttgca caatggcttc caaaaggcaa
    30301 acggccctca cgtccaagtg gacgtaaagg ctaaaccctt cagggtgaat ctcctctata
    30361 aacattccag caccttcaac catgcccaaa taattctcat ctcgccacct tctcaatata
    30421 tctctaagca aatcccgaat attaagtccg gccattgtaa aaatctgctc cagagcgccc
    30481 tccaccttca gcctcaagca gcgaatcatg attgcaaaaa ttcaggttcc tcacagacct
    30541 gtataagatt caaaagcgga acattaacaa aaataccgcg atcccgtagg tcccttcgca
    30601 gggccagctg aacataatcg tgcaggtctg cacggaccag cgcggccact tccccgccag
    30661 gaaccatgac aaaagaaccc acactgatta tgacacgcat actcggagct atgctaacca
    30721 gcgtagcccc gatgtaagct tgttgcatgg gcggcgatat aaaatgcaag gtgctgctca
    30781 aaaaatcagg caaagcctcg cgcaaaaaag aaagcacatc gtagtcatgc tcatgcagat
    30841 aaaggcaggt aagctccgga accaccacag aaaaagacac catttttctc tcaaacatgt
    30901 ctgcgggttt ctgcataaac acaaaataaa ataacaaaaa aacatttaaa cattagaagc
    30961 ctgtcttaca acaggaaaaa caacccttat aagcataaga cggactacgg ccatgccggc
    31021 gtgaccgtaa aaaaactggt caccgtgatt aaaaagcacc accgacagct cctcggtcat
    31081 gtccggagtc ataatgtaag actcggtaaa cacatcaggt tgattcacat cggtcagtgc
    31141 taaaaagcga ccgaaatagc ccgggggaat acatacccgc aggcgtagag acaacattac
    31201 agcccccata ggaggtataa caaaattaat aggagagaaa aacacataaa cacctgaaaa
    31261 accctcctgc ctaggcaaaa tagcaccctc ccgctccaga acaacataca gcgcttccac
    31321 agcggcagcc ataacagtca gccttaccag taaaaaagaa aacctattaa aaaaacacca
    31381 ctcgacacgg caccagctca atcagtcaca gtgtaaaaaa gggccaagtg cagagcgagt
    31441 atatatagga ctaaaaaatg acgtaacggt taaagtccac aaaaaacacc cagaaaaccg
    31501 cacgcgaacc tacgcccaga aacgaaagcc aaaaaaccca caacttcctc aaatcgtcac
    31561 ttccgttttc ccacgttacg tcacttccca ttttaagaaa actacaattc ccaacacata
    31621 caagttactc cgccctaaaa cctacgtcac ccgccccgtt cccacgcccc gcgccacgtc
    31681 acaaactcca ccccctcatt atcatattgg cttcaatcca aaataaggta tattattgat
    31741 gatgttaatt aacatgcatg gatccgtata ctggcttaac tatgcggcat cagagcagat
    31801 tgtactgaga gtgcaccata tgcggtgtga aataccgcac agatgcgtaa ggagaaaata
    31861 ccgcatcagg cgctcttccg cttcctcgct cactgactcg ctgcgctcgg tcgttcggct
    31921 gcggcgagcg gtatcagctc actcaaaggc ggtaatacgg ttatccacag aatcagggga
    31981 taacgcagga aagaacatgt gagcaaaagg ccagcaaaag gccaggaacc gtaaaaaggc
    32041 cgcgttgctg gcgtttttcc ataggctccg cccccctgac gagcatcaca aaaatcgacg
    32101 ctcaagtcag aggtggcgaa acccgacagg actataaaga taccaggcgt ttccccctgg
    32161 aagctccctc gtgcgctctc ctgttccgac cctgccgctt accggatacc tgtccgcctt
    32221 tctcccttcg ggaagcgtgg cgctttctca tagctcacgc tgtaggtatc tcagttcggt
    32281 gtaggtcgtt cgctccaagc tgggctgtgt gcacgaaccc cccgttcagc ccgaccgctg
    32341 cgccttatcc ggtaactatc gtcttgagtc caacccggta agacacgact tatcgccact
    32401 ggcagcagcc actggtaaca ggattagcag agcgaggtat gtaggcggtg ctacagagtt
    32461 cttgaagtgg tggcctaact acggctacac tagaaggaca gtatttggta tctgcgctct
    32521 gctgaagcca gttaccttcg gaaaaagagt tggtagctct tgatccggca aacaaaccac
    32581 cgctggtagc ggtggttttt ttgtttgcaa gcagcagatt acgcgcagaa aaaaaggatc
    32641 tcaagaagat cctttgatct tttctacggg gtctgacgct cagtggaacg aaaactcacg
    32701 ttaagggatt ttggtcatga gattatcaaa aaggatcttc acctagatcc ttttaaatta
    32761 aaaatgaagt tttaaatcaa tctaaagtat atatgagtaa acttggtctg acagttacca
    32821 atgcttaatc agtgaggcac ctatctcagc gatctgtcta tttcgttcat ccatagttgc
    32881 ctgactcccc gtcgtgtaga taactacgat acgggagggc ttaccatctg gccccagtgc
    32941 tgcaatgata ccgcgagacc cacgctcacc ggctccagat ttatcagcaa taaaccagcc
    33001 agccggaagg gccgagcgca gaagtggtcc tgcaacttta tccgcctcca tccagtctat
    33061 taattgttgc cgggaagcta gagtaagtag ttcgccagtt aatagtttgc gcaacgttgt
    33121 tgccattgct gcagccatga gattatcaaa aaggatcttc acctagatcc ttttcacgta
    33181 gaaagccagt ccgcagaaac ggtgctgacc ccggatgaat gtcagctact gggctatctg
    33241 gacaagggaa aacgcaagcg caaagagaaa gcaggtagct tgcagtgggc ttacatggcg
    33301 atagctagac tgggcggttt tatggacagc aagcgaaccg gaattgccag ctggggcgcc
    33361 ctctggtaag gttgggaagc cctgcaaagt aaactggatg gctttcttgc cgccaaggat
    33421 ctgatggcgc aggggatcaa gctctgatca agagacagga tgaggatcgt ttcgcatgat
    33481 tgaacaagat ggattgcacg caggttctcc ggccgcttgg gtggagaggc tattcggcta
    33541 tgactgggca caacagacaa tcggctgctc tgatgccgcc gtgttccggc tgtcagcgca
    33601 ggggcgcccg gttctttttg tcaagaccga cctgtccggt gccctgaatg aactgcaaga
    33661 cgaggcagcg cggctatcgt ggctggccac gacgggcgtt ccttgcgcag ctgtgctcga
    33721 cgttgtcact gaagcgggaa gggactggct gctattgggc gaagtgccgg ggcaggatct
    33781 cctgtcatct caccttgctc ctgccgagaa agtatccatc atggctgatg caatgcggcg
    33841 gctgcatacg cttgatccgg ctacctgccc attcgaccac caagcgaaac atcgcatcga
    33901 gcgagcacgt actcggatgg aagccggtct tgtcgatcag gatgatctgg acgaagagca
    33961 tcaggggctc gcgccagccg aactgttcgc caggctcaag gcgagcatgc ccgacggcga
    34021 ggatctcgtc gtgacccatg gcgatgcctg cttgccgaat atcatggtgg aaaatggccg
    34081 cttttctgga ttcatcgact gtggccggct gggtgtggcg gaccgctatc aggacatagc
    34141 gttggctacc cgtgatattg ctgaagagct tggcggcgaa tgggctgacc gcttcctcgt
    34201 gctttacggt atcgccgctc ccgattcgca gcgcatcgcc ttctatcgcc ttcttgacga
    34261 gttcttctga attttgttaa aatttttgtt aaatcagctc attttttaac caataggccg
    34321 aaatcggcaa aatcccttat aaatcaaaag aatagaccga gatagggttg agtgttgttc
    34381 cagtttggaa caagagtcca ctattaaaga acgtggactc caacgtcaaa gggcgaaaaa
    34441 ccgtctatca gggcgatggc ccactacgtg aaccatcacc ctaatcaagt tttttggggt
    34501 cgaggtgccg taaagcacta aatcggaacc ctaaagggag cccccgattt agagcttgac
    34561 ggggaaagcc ggcgaacgtg gcgagaaagg aagggaagaa agcgaaagga gcgggcgcta
    34621 gggcgctggc aagtgtagcg gtcacgctgc gcgtaaccac cacacccgcc gcgcttaatg
    34681 cgccgctaca gggc
//
