LOCUS       sequence-245447-         792 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Hypoxia response element real-time luciferase reporter.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, 
            Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, 
            Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV
  TITLE     Acid Suspends the Circadian Clock in Hypoxia through Inhibition of 
            mTOR.
  JOURNAL   Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009.
            Epub 2018 May 31.
  PUBMED    29861175
REFERENCE   2  (bases 1 to 792)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.cell.2018.05.009"; journalName: "Cell"; date: 
            "2018-06-28- 28"; volume: "174"; issue: "1"; pages: "72-87.e32"
COMMENT     Sequence Label: pGL4.22-PGK1-HRE::dLUC
FEATURES             Location/Qualifiers
     source          1..792
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      168..177
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 acatttctct ggcctaactg gccggtaccg agctctgtca cgtcctgcac gactctagtt
       61 gtcacgtcct gcacgactct agttgtcacg tcctgcacga cgctagctcg aggatatcaa
      121 gatctggcct cggcggccaa gcttggcaat ccggtactgt tggtaaagcc accatggaag
      181 atgccaaaaa cattaagaag ggcccagcgc cattctaccc actcgaagac gggaccgccg
      241 gcgagcagct gcacaaagcc atgaagcgct acgccctggt gcccggcacc atcgccttta
      301 ccgacgcaca tatcgaggtg gacattacct acgccgagta cttcgagatg agcgttcggc
      361 tggcagaagc tatgaagcgc tatgggctga atacaaacca tcggatcgtg gtgtgcagcg
      421 agaatagctt gcagttcttc atgcccgtgt tgggtgccct gttcatcggt gtggctgtgg
      481 ccccagctaa cgacatctac aacgagcgcg agctgctgaa cagcatgggc atcagccagc
      541 ccaccgtcgt attcgtgagc aagaaagggc tgcaaaagat cctcaacgtg caaaagaagc
      601 taccgatcat acaaaagatc atcatcatgg atagcaagac cgactaccag ggcttccaaa
      661 gcatgtacac cttcgtgact tcccatttgc cacccggctt caacgagtac gacttcgtgc
      721 ccgagagctt cgaccgggac aaaaccatcg ccctgatcat gaacagtagt ggcagtaccg
      781 gattgcccaa gg
//
