LOCUS       sequence-245448-         698 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Hypoxia response element real-time luciferase reporter.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, 
            Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, 
            Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV
  TITLE     Acid Suspends the Circadian Clock in Hypoxia through Inhibition of 
            mTOR.
  JOURNAL   Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009.
            Epub 2018 May 31.
  PUBMED    29861175
REFERENCE   2  (bases 1 to 698)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.cell.2018.05.009"; journalName: "Cell"; date: 
            "2018-06-28- 28"; volume: "174"; issue: "1"; pages: "72-87.e32"
COMMENT     Sequence Label: pGL4.22-VEGF-HRE::dLUC
FEATURES             Location/Qualifiers
     source          1..698
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      290..299
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 ggcctaactg gccggtacct gagctcgcta gcctcgagcc acagtgcata cgtgggctcc
       61 aacaggtcct cttgtcgagc cacagtgcat acgtgggctc caacaggtcc tcttgtcgag
      121 ccacagtgca tacgtgggct ccaacaggtc ctcttgtcga gccacagtgc atacgtgggc
      181 tccaacaggt cctcttgtcg agccacagtg catacgtggg ctccaacagg tcctcttgtc
      241 gagatctggc ctcggcggcc aagcttggca atccggtact gttggtaaag ccaccatgga
      301 agatgccaaa aacattaaga agggcccagc gccattctac ccactcgaag acgggaccgc
      361 cggcgagcag ctgcacaaag ccatgaagcg ctacgccctg gtgcccggca ccatcgcctt
      421 taccgacgca catatcgagg tggacattac ctacgccgag tacttcgaga tgagcgttcg
      481 gctggcagaa gctatgaagc gctatgggct gaatacaaac catcggatcg tggtgtgcag
      541 cgagaatagc ttgcagttct tcatgcccgt gttgggtgcc ctgttcatcg gtgtggctgt
      601 ggccccagct aacgacatct acaacgagcg cgagctgctg aacagcatgg gcatcagcca
      661 gcccaccgtc gtattcgtga gcaagaaagg gctgcaaa
//
