LOCUS       sequence-24651-e         642 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW
  TITLE     Oncogenic ras provokes premature cell senescence associated with 
            accumulation of p53 and p16INK4a.
  JOURNAL   Cell. 1997 Mar 7. 88(5):593-602.
  PUBMED    9054499
REFERENCE   2  (bases 1 to 642)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Cell. 1997 
            Mar 7. 88(5):593-602."
COMMENT     Sequence Label: pWZL hygro H-Ras V12
FEATURES             Location/Qualifiers
     source          1..642
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             join(49..81,82..84,85..618)
                     /codon_start=1
                     /product="human oncoprotein generated by the G12V mutation 
                     in the small GTPase H-Ras"
                     /label=H-Ras (G12V)
                     /translation="MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVV
                     IDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVK
                     DSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI
                     RQHKLRKLNPPDESGPGCMSCKCVLS"
ORIGIN
        1 gatccngtgt ggtggtacag cttggggggc cagggccggg gccgagcgat gacggaatat
       61 aagctggtgg tggtgggcgc cgtcggtgtg ggcaagagtg cgctgaccat ccagctgatc
      121 cagaaccatt ttgtggacga atacgacccc actatagagg attcctaccg gaagcaggtg
      181 gtcattgatg gggagacgtg cctgttggac atcctggata ccgccggcca ggaggagtac
      241 agcgccatgc gggaccagta catgcgcacc ggggagggct tcctgtgtgt gtttgccatc
      301 aacaacacca agtcttttga ggacatccac cagtacaggg agcagatcaa acgggtgaag
      361 gactcggatg acgtgcccat ggtgctggtg gggaacaagt gtgacctggc tgcacgcact
      421 gtggaatctc ggcaggctca ggacctcgcc cgaagctacg gcatccccta catcgagacc
      481 tcggccaaga cccggcaggg agtggaggat gccttctaca cgttggtgcg tgagatccgg
      541 cagcacaagc tgcggaagct gaaccctcct gatgagagtg gccccggctg catgagctgc
      601 aagtgtgtgc tctcctgacg cagcacaagc tcaggacatg ga
//
