LOCUS       sequence-26990-e         726 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Dajee M, Tarutani M, Deng H, Cai T, Khavari PA
  TITLE     Epidermal Ras blockade demonstrates spatially localized Ras 
            promotion of proliferation and inhibition of differentiation
  JOURNAL   Oncogene. 2002 Feb 28;21(10):1527-38
  PUBMED    11896581
REFERENCE   2  (bases 1 to 726)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Oncogene.";
            date: "2002-02-28"; volume: "21(10)"; pages: "1527-3"
COMMENT     Sequence Label: LZRS ERTm RasV12
FEATURES             Location/Qualifiers
     source          1..726
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             complement(join(14..547,548..550,551..583))
                     /codon_start=1
                     /product="human oncoprotein generated by the G12V mutation 
                     in the small GTPase H-Ras"
                     /label=H-Ras (G12V)
                     /translation="MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVV
                     IDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVK
                     DSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI
                     RQHKLRKLNPPDESGPGCMSCKCVLS"
ORIGIN
        1 atatcgaatt gcgtcaggag agcacacact tgcagctcat gcagccgggg ccactctcat
       61 caggagggtt cagcttccgc agcttgtgct gccggatctc acgcaccaac gtgtagaagg
      121 catcctccac tccctgccgg gtcttggccg aggtctcgat gtaggggatg ccgtagcttc
      181 gggcgaggtc ctgagcctgc cgagattcca cagtgcgtgc agccaggtca cacttgttcc
      241 ccaccagcac catgggcacg tcatccgagt ccttcacccg tttgatctgc tccctgtact
      301 ggtggatgtc ctcaaaagac ttggtgttgt tgatggcaaa cacacacagg aagccctccc
      361 cggtgcgcat gtactggtcc cgcatggcgc tgtactcctc ctggccggcg gtatccagga
      421 tgtccaacag gcacgtctcc ccatcaatga ccacctgctt ccggtaggaa tcctctatag
      481 tggggtcgta ttcgtccaca aaatggttct ggatcagctg gatggtcagc gcactcttgc
      541 ccacaccgac ggcgcccacc accaccagct tatattccgt catggaattc aggcctccac
      601 gtgggatatc gttggggaag ccctctgctt ccgggggtat gtagtaggtt tgtaaggaat
      661 gtgctgaagt ggagctggtg gtggccagct gggtctggct gggctcctct gggggcactc
      721 ccatgc
//
