LOCUS       sequence-26996-e         865 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Dajee M, Tarutani M, Deng H, Cai T, Khavari PA
  TITLE     Epidermal Ras blockade demonstrates spatially localized Ras 
            promotion of proliferation and inhibition of differentiation
  JOURNAL   Oncogene. 2002 Feb 28;21(10):1527-38
  PUBMED    11896581
REFERENCE   2  (bases 1 to 865)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Oncogene.";
            date: "2002-02-28"; volume: "21(10)"; pages: "1527-3"
COMMENT     Sequence Label: LZRS-RasG12V
FEATURES             Location/Qualifiers
     source          1..865
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             join(84..116,117..119,120..653)
                     /codon_start=1
                     /product="human oncoprotein generated by the G12V mutation 
                     in the small GTPase H-Ras"
                     /label=H-Ras (G12V)
                     /translation="MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVV
                     IDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVK
                     DSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI
                     RQHKLRKLNPPDESGPGCMSCKCVLS"
ORIGIN
        1 cnnnnggaca cggggngaca tcctctgact gccggatccc agtgtggtgg tacagcttgg
       61 ggggccaggg ccggggccga gcgatgacgg aatataagct ggtggtggtg ggcgccgtcg
      121 gtgtgggcaa gagtgcgctg accatccagc tgatccagaa ccattttgtg gacgaatacg
      181 accccactat agaggattcc taccggaagc aggtggtcat tgatggggag acgtgcctgt
      241 tggacatcct ggataccgcc ggccaggagg agtacagcgc catgcgggac cagtacatgc
      301 gcaccgggga gggcttcctg tgtgtgtttg ccatcaacaa caccaagtct tttgaggaca
      361 tccaccagta cagggagcag atcaaacggg tgaaggactc ggatgacgtg cccatggtgc
      421 tggtggggaa caagtgtgac ctggctgcac gcactgtgga atctcggcag gctcaggacc
      481 tcgcccgaag ctacggcatc ccctacatcg agacctcggc caagacccgg cagggagtgg
      541 aggatgcctt ctacacgttg gtgcgtgaga tccggcagca caagctgcgg aagctgaacc
      601 ctcctgatga gagtggcccc ggctgcatga gctgcaagtg tgtgctctcc tgacgcagca
      661 caagctcagg acatggaggt gccggatgca ggaaggaggt gcagacggaa ggaggaggaa
      721 ggaaggacgg aagcanggaa ggaaggaagg gctgctggag cccagtcacc ccccaagctg
      781 taggaattcn agctgagcgc cggtcgctac cattacagtt ggtctggtgt caaaataata
      841 taaccgggca ggcatgtctg ccgtt
//
