LOCUS       sequence-273595-         960 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  expresses PTPN11 T73I.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Cremer A, Ellegast JM, Alexe G, Frank ES, Ross L, Chu SH, Pikman Y, 
            Robichaud A, Goodale A, Haupl B, Mohr S, Rao AV, Walker AR, Blachly 
            JS, Piccioni F, Armstrong SA, Byrd JC, Oellerich T, Stegmaier K
  TITLE     Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia.
  JOURNAL   Cancer Discov. 2020 Feb;10(2):214-231. doi: 
            10.1158/2159-8290.CD-19-0209. Epub 2019 Nov 26.
  PUBMED    31771968
REFERENCE   2  (bases 1 to 960)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1158/2159-8290.CD-19-0209"; journalName: "Cancer Discov"; date: 
            "2020-02"; volume: "10"; issue: "2"; pages: "214-231"
COMMENT     Sequence Label: pLX307/PTPN11 T73I
FEATURES             Location/Qualifiers
     source          1..960
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    29..53
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 gtgtcgtgag gctagcatcg attgatcaac aagtttgtac aaaaaagcag gctccgcggc
       61 cgcccccttc accatggcat cgcggagatg gtttcaccca aatatcactg gtgtggaggc
      121 agaaaaccta ctgttgacaa gaggagttga tggcagtttt ttggcaaggc ctagtaaaag
      181 taaccctgga gacttcacac tttccgttag aagaaatgga gctgtcaccc acatcaagat
      241 tcagaacact ggtgattact atgacctgta tggaggggag aaatttgcca ttttggctga
      301 gttggtccag tattacatgg aacatcacgg gcaattaaaa gagaagaatg gagatgtcat
      361 tgagcttaaa tatcctctga actgtgcaga tcctacctct gaaaggtggt ttcatggaca
      421 tctctctggg aaagaagcag agaaattatt aactgaaaaa ggaaaacatg gtagttttct
      481 tgtacgagag agccagagcc accctggaga ttttgttctt tctgtgcgca ctggtgatga
      541 caaaggggag agcaatgacg gcaagtctaa agtgacccat gttatgattc gctgtcagga
      601 actgaaatac gacgttggtg gaggagaacg gtttgattct ttgacagatc ttgtggaaca
      661 ttataagaag aatcctatgg tggaaacatt gggtacagta ctacaactca agcagcccct
      721 taacacgact cgtataaatg ctgctgaaat agaaagcaga gttcgagaac taagcaaatt
      781 agctgagacc acagataaag tcaaacaagg cttttgggaa gaatttgaga cactacaaca
      841 acaggagtgc aaacttctct acagccgaaa agagggtcaa aggcaagaaa acaaaaacaa
      901 aaatagatat aaaaacatcc tgccctttga tcataccagg gttgtcctac acgatggtga
//
