LOCUS       sequence-292134-        1408 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Lentiviral overexpression of MYC in mammalian cells..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1408)
  AUTHORS   Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen
            C, Hu C, Sheng Y, Wang Y, Wunderlich M, Zhang B, Dore LC, Su R, Deng
            X, Ferchen K, Li C, Sun M, Lu Z, Jiang X, Marcucci G, Mulloy JC, 
            Yang J, Qian Z, Wei M, He C, Chen J
  TITLE     METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and 
            Promotes Leukemogenesis via mRNA m(6)A Modification.
  JOURNAL   Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9. doi: 
            10.1016/j.stem.2017.11.016. Epub 2017 Dec 28.
  PUBMED    29290617
REFERENCE   2  (bases 1 to 1408)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.stem.2017.11.016"; journalName: "Cell Stem Cell"; date: 
            "2018-02-1- 1"; volume: "22"; issue: "2"; pages: "191-205.e9"
COMMENT     Sequence Label: pmiRA1-MYC
FEATURES             Location/Qualifiers
     source          1..1408
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             15..41
                     /codon_start=1
                     /product="HA (human influenza hemagglutinin) epitope tag"
                     /label=HA
                     /translation="YPYDVPDYA"
     CDS             45..71
                     /codon_start=1
                     /product="HA (human influenza hemagglutinin) epitope tag"
                     /label=HA
                     /translation="YPYDVPDYA"
     CDS             81..1400
                     /codon_start=1
                     /product="human c-Myc proto-oncogene"
                     /label=c-Myc
                     /translation="MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP
                     SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTE
                     LLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPN
                     PARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDS
                     LLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGS
                     PSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNR
                     KCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKA
                     TAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA"
ORIGIN
        1 tctagaccac catgtaccct tacgacgtgc ccgactacgc cgggtaccct tacgacgtgc
       61 ccgactacgc cggatccacc atgcccctca acgttagctt caccaacagg aactatgacc
      121 tcgactacga ctcggtgcag ccgtatttct actgcgacga ggaggagaac ttctaccagc
      181 agcagcagca gagcgagctg cagcccccgg cgcccagcga ggatatctgg aagaaattcg
      241 agctgctgcc caccccgccc ctgtccccta gccgccgctc cgggctctgc tcgccctcct
      301 acgttgcggt cacacccttc tcccttcggg gagacaacga cggcggtggc gggagcttct
      361 ccacggccga ccagctggag atggtgaccg agctgctggg aggagacatg gtgaaccaga
      421 gtttcatctg cgacccggac gacgagacct tcatcaaaaa catcatcatc caggactgta
      481 tgtggagcgg cttctcggcc gccgccaagc tcgtctcaga gaagctggcc tcctaccagg
      541 ctgcgcgcaa agacagcggc agcccgaacc ccgcccgcgg ccacagcgtc tgctccacct
      601 ccagcttgta cctgcaggat ctgagcgccg ccgcctcaga gtgcatcgac ccctcggtgg
      661 tcttccccta ccctctcaac gacagcagct cgcccaagtc ctgcgcctcg caagactcca
      721 gcgccttctc tccgtcctcg gattctctgc tctcctcgac ggagtcctcc ccgcagggca
      781 gccccgagcc cctggtgctc catgaggaga caccgcccac caccagcagc gactctgagg
      841 aggaacaaga agatgaggaa gaaatcgatg ttgtttctgt ggaaaagagg caggctcctg
      901 gcaaaaggtc agagtctgga tcaccttctg ctggaggcca cagcaaacct cctcacagcc
      961 cactggtcct caagaggtgc cacgtctcca cacatcagca caactacgca gcgcctccct
     1021 ccactcggaa ggactatcct gctgccaaga gggtcaagtt ggacagtgtc agagtcctga
     1081 gacagatcag caacaaccga aaatgcacca gccccaggtc ctcggacacc gaggagaatg
     1141 tcaagaggcg aacacacaac gtcttggagc gccagaggag gaacgagcta aaacggagct
     1201 tttttgccct gcgtgaccag atcccggagt tggaaaacaa tgaaaaggcc cccaaggtag
     1261 ttatccttaa aaaagccaca gcatacatcc tgtccgtcca agcagaggag caaaagctca
     1321 tttctgaaga ggacttgttg cggaaacgac gagaacagtt gaaacacaaa cttgaacagc
     1381 tacggaactc ttgtgcgtaa gcggccgc
//
