LOCUS       sequence-292143-        1403 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Overexpression of WT METTL14 in mammalian cells..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen
            C, Hu C, Sheng Y, Wang Y, Wunderlich M, Zhang B, Dore LC, Su R, Deng
            X, Ferchen K, Li C, Sun M, Lu Z, Jiang X, Marcucci G, Mulloy JC, 
            Yang J, Qian Z, Wei M, He C, Chen J
  TITLE     METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and 
            Promotes Leukemogenesis via mRNA m(6)A Modification.
  JOURNAL   Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9. doi: 
            10.1016/j.stem.2017.11.016. Epub 2017 Dec 28.
  PUBMED    29290617
REFERENCE   2  (bases 1 to 1403)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.stem.2017.11.016"; journalName: "Cell Stem Cell"; date: 
            "2018-02-1- 1"; volume: "22"; issue: "2"; pages: "191-205.e9"
COMMENT     Sequence Label: pCDH-METTL14-WT
FEATURES             Location/Qualifiers
     source          1..1403
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             9..35
                     /codon_start=1
                     /product="HA (human influenza hemagglutinin) epitope tag"
                     /label=HA
                     /translation="YPYDVPDYA"
ORIGIN
        1 ccaccatgta cccatacgat gttccagatt acgctgatag ccgcttgcag gagatccggg
       61 agcggcagaa gttacggcga cagctcctcg cgcagcagtt gggagctgaa agtgccgaca
      121 gcattggtgc cgtgttaaat agcaaagatg agcagagaga aattgctgaa acaagagaaa
      181 cttgcagggc ttcctatgat acctctgctc caaatgcaaa acgtaagtat ctggatgaag
      241 gagagacaga tgaagacaaa atggaagaat ataaggatga actagaaatg caacaggatg
      301 aagaaaattt gccatatgaa gaagagattt acaaagattc tagtactttt cttaagggaa
      361 cacagagctt aaatccccat aatgattact gccaacattt tgtagacact ggacatagac
      421 ctcagaattt catcagggat gtaggtttag ctgacagatt tgaagaatat cctaaactga
      481 gggagctcat caggctaaag gatgagttaa tagctaaatc taacactcct cccatgtact
      541 tacaagccga tatagaagcc tttgacatca gagaactaac acccaaattt gatgtgattc
      601 ttctggaacc ccctttagaa gaatattaca gagaaactgg catcactgct aatgaaaaat
      661 gctggacttg ggatgatatt atgaagttag aaattgatga gattgcagca cctcgatcat
      721 ttatttttct ctggtgtggt tctggggagg ggttggacct tggaagagtg tgtttacgaa
      781 aatggggtta cagaagatgt gaagatattt gttggattaa aaccaataaa aacaatcctg
      841 ggaagactaa gactttagat ccaaaggctg tctttcagag aacaaaggaa cactgcctca
      901 tggggatcaa aggaactgtg aagcgtagca cagacgggga cttcattcat gctaatgttg
      961 acattgactt aattatcaca gaagaacctg aaattggcaa tatagaaaaa cctgtagaaa
     1021 tttttcatat aattgagcat ttttgtcttg gtagaagacg ccttcatcta tttggaagag
     1081 atagtacaat tcgaccaggc tggctcacag ttggaccaac gcttacaaat agcaactaca
     1141 atgcagaaac atatgcatcc tatttcagtg ctcctaattc ctacttgact ggttgtacag
     1201 aagaaattga gagacttcga ccaaaatcgc ctcctcccaa atctaaatct gaccgaggag
     1261 gtggagctcc cagaggtgga ggaagaggtg gaacttctgc tggccgtgga cgagaaagaa
     1321 atagatctaa cttccgagga gaaagaggtg gctttagagg gggccgtgga ggagcacaca
     1381 gaggtggctt tccacctcga taa
//
