LOCUS       sequence-292222-        9356 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  Expression of the catalytically impaired JAK1-P1084A mutant 
            (corresponding to TYK2-P1104A).
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 9356)
  AUTHORS   Li Z, Gakovic M, Ragimbeau J, Eloranta ML, Ronnblom L, Michel F, 
            Pellegrini S
  TITLE     Two rare disease-associated Tyk2 variants are catalytically impaired
            but signaling competent.
  JOURNAL   J Immunol. 2013 Mar 1;190(5):2335-44. doi: 10.4049/jimmunol.1203118.
            Epub 2013 Jan 28.
  PUBMED    23359498
REFERENCE   2  (bases 1 to 9356)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.4049/jimmunol.1203118"; journalName: "J Immunol"; date: 
            "2013-03-1- 1"; volume: "190"; issue: "5"; pages: "2335-44"
COMMENT     Sequence Label: pRC/CMV-JAK1P1084A-VSV
FEATURES             Location/Qualifiers
     source          1..9356
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     enhancer        1..380
                     /label=CMV enhancer
                     /note="human cytomegalovirus immediate early enhancer"
     promoter        381..584
                     /label=CMV promoter
                     /note="human cytomegalovirus (CMV) immediate early 
                     promoter"
     primer_bind     535..555
                     /label=CMV-F
                     /note="Human CMV immediate early promoter, forward primer"
     primer_bind     629..648
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        629..647
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
     primer_bind     738..754
                     /label=pBluescriptKS
                     /note="For pBluescript vector"
     primer_bind     739..755
                     /label=KS primer
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     CDS             4514..4546
                     /codon_start=1
                     /product="epitope tag from vesicular stomatitis virus G 
                     protein"
                     /label=VSV-G tag
                     /translation="YTDIEMNRLGK"
     promoter        complement(4581..4599)
                     /label=SP6 promoter
                     /note="promoter for bacteriophage SP6 RNA polymerase"
     primer_bind     complement(4582..4599)
                     /label=SP6
                     /note="SP6 promoter, forward primer"
     primer_bind     complement(4619..4636)
                     /label=BGH-rev
                     /note="Bovine growth hormone terminator, reverse primer. 
                     Also called BGH reverse"
     polyA_signal    4625..4849
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     rep_origin      4895..5408
                     /direction=RIGHT
                     /label=M13 ori
                     /note="M13 bacteriophage origin of replication; arrow 
                     indicates direction of (+) strand synthesis"
     primer_bind     complement(4982..5001)
                     /label=F1ori-R
                     /note="F1 origin, reverse primer"
     primer_bind     5192..5213
                     /label=F1ori-F
                     /note="F1 origin, forward primer"
     primer_bind     complement(5431..5451)
                     /label=pBABE 3'
                     /note="SV40 enhancer, reverse primer for pBABE vectors"
     promoter        5436..5765
                     /label=SV40 promoter
                     /note="SV40 enhancer and early promoter"
     rep_origin      5616..5751
                     /label=SV40 ori
                     /note="SV40 origin of replication"
     CDS             5832..6626
                     /codon_start=1
                     /gene="aph(3')-II (or nptII)"
                     /product="aminoglycoside phosphotransferase from Tn5"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKARMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     primer_bind     complement(5886..5905)
                     /label=Neo-R
                     /note="Neomycin resistance gene, reverse primer"
     primer_bind     6496..6515
                     /label=Neo-F
                     /note="Neomycin resistance gene, forward primer"
     polyA_signal    6800..6934
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     primer_bind     complement(6837..6856)
                     /label=SV40pA-R
                     /note="SV40 polyA, reverse primer"
     primer_bind     6891..6910
                     /label=EBV-rev
                     /note="SV40 polyA terminator, reverse primer"
     primer_bind     complement(6965..6981)
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     complement(6965..6981)
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     primer_bind     complement(6978..7000)
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     protein_bind    6989..7005
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     promoter        complement(join(7013..7019,7020..7037,7038..7043))
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    7058..7079
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     primer_bind     complement(7196..7213)
                     /label=L4440
                     /note="L4440 vector, forward primer"
     rep_origin      complement(7367..7955)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     complement(7447..7466)
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     CDS             complement(join(8126..8917,8918..8986))
                     /codon_start=1
                     /gene="bla"
                     /product="beta-lactamase"
                     /label=AmpR
                     /note="confers resistance to ampicillin, carbenicillin, and
                     related antibiotics"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     primer_bind     8749..8768
                     /label=Amp-R
                     /note="Ampicillin resistance gene, reverse primer"
     promoter        complement(8987..9091)
                     /gene="bla"
                     /label=AmpR promoter
     primer_bind     complement(9166..9185)
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
ORIGIN
        1 gacattgatt attgactagt tattaatagt aatcaattac ggggtcatta gttcatagcc
       61 catatatgga gttccgcgtt acataactta cggtaaatgg cccgcctggc tgaccgccca
      121 acgacccccg cccattgacg tcaataatga cgtatgttcc catagtaacg ccaataggga
      181 ctttccattg acgtcaatgg gtggagtatt tacggtaaac tgcccacttg gcagtacatc
      241 aagtgtatca tatgccaagt acgcccccta ttgacgtcaa tgacggtaaa tggcccgcct
      301 ggcattatgc ccagtacatg accttatggg actttcctac ttggcagtac atctacgtat
      361 tagtcatcgc tattaccatg gtgatgcggt tttggcagta catcaatggg cgtggatagc
      421 ggtttgactc acggggattt ccaagtctcc accccattga cgtcaatggg agtttgtttt
      481 ggcaccaaaa tcaacgggac tttccaaaat gtcgtaacaa ctccgcccca ttgacgcaaa
      541 tgggcggtag gcgtgtacgg tgggaggtct atataagcag agctctctgg ctaactagag
      601 aacccactgc ttactggctt atcgaaatta atacgactca ctatagggag acccaagctt
      661 ggtaccgagc tcggatccac tagtaacggc cgccagtgtg ctggaattct gcagatatcc
      721 atcacactgg cggccgctcg aggtcgacgg tatcgataag cttgataatt cggcacgagg
      781 cagacagtgc gggcctgcgc ccagtcccgg ctgtcctcgc cgcgacccct cctcagccct
      841 gggcgcgcgc acgctggggc cccgcggggc tggccgccta gcgagcctgc cggtcgaccc
      901 cagccagcgc agcgacgggg cgctgcctgg cccaggcgca cacggaagtg cgcttctctg
      961 aagtagcttt ggaaagtaga gaagaaaatc cagtttgctt cttggagaac actggacagc
     1021 tgaataaatg cagtatctaa atataaaaga ggactgcaat gccatggctt tctgtgctaa
     1081 aatgaggagc tccaagaaga ctgaggtgaa cctggaggcc cctgagccag gggtggaagt
     1141 gatcttctat ctgtcggaca gggagcccct ccggctgggc agtggagagt acacagcaga
     1201 ggaactgtgc atcagggctg cacaggcatg ccgtatctct cctctttgtc acaacctctt
     1261 tgccctgtat gacgagaaca ccaagctctg gtatgctcca aatcgcacca tcaccgttga
     1321 tgacaagatg tccctccggc tccactaccg gatgaggttc tatttcacca attggcatgg
     1381 aaccaacgac aatgagcagt cagtgtggcg tcattctcca aagaagcaga aaaatggcta
     1441 cgagaaaaaa aagattccag atgcaacccc tctccttgat gccagctcac tggagtatct
     1501 gtttgctcag ggacagtatg atttggtgaa atgcctggct cctattcgag accccaagac
     1561 cgagcaggat ggacatgata ttgagaacga gtgtctaggg atggctgtcc tggccatctc
     1621 acactatgcc atgatgaaga agatgcagtt gccagaactg cccaaggaca tcagctacaa
     1681 gcgatatatt ccagaaacat tgaataagtc catcagacag aggaaccttc tcaccaggat
     1741 gcggataaat aatgttttca aggatttcct aaaggaattt aacaacaaga ccatttgtga
     1801 cagcagcgtg tccacgcatg acctgaaggt gaaatacttg gctaccttgg aaactttgac
     1861 aaaacattac ggtgctgaaa tatttgagac ttccatgtta ctgatttcat cagaaaatga
     1921 gatgaattgg tttcattcga atgacggtgg aaacgttctc tactacgaag tgatggtgac
     1981 tgggaatctt ggaatccagt ggaggcataa accaaatgtt gtttctgttg aaaaggaaaa
     2041 aaataaactg aagcggaaaa aactggaaaa taaacacaag aaggatgagg agaaaaacaa
     2101 gatccgggaa gagtggaaca atttttctta cttccctgaa atcactcaca ttgtaataaa
     2161 ggagtctgtg gtcagcatta acaagcagga caacaagaaa atggaactga agctctcttc
     2221 ccacgaggag gccttgtcct ttgtgtccct ggtagatggc tacttccggc tcacagcaga
     2281 tgcccatcat tacctctgca ccgacgtggc ccccccgttg atcgtccaca acatacagaa
     2341 tggctgtcat ggtccaatct gtacagaata cgccatcaat aaattgcggc aagaaggaag
     2401 cgaggagggg atgtacgtgc tgaggtggag ctgcaccgac tttgacaaca tcctcatgac
     2461 cgtcacctgc tttgagaagt ctgagcaggt gcagggtgcc cagaagcagt tcaagaactt
     2521 tcagatcgag gtgcagaagg gccgctacag tctgcacggt tcggaccgca gcttccccag
     2581 cttgggagac ctcatgagcc acctcaagaa gcagatcctg cgcacggata acatcagctt
     2641 catgctaaaa cgctgctgcc agcccaagcc ccgagaaatc tccaacctgc tggtggctac
     2701 taagaaagcc caggagtggc agcccgtcta ccccatgagc cagctgagtt tcgatcggat
     2761 cctcaagaag gatctggtgc agggcgagca ccttgggaga ggcacgagaa cacacatcta
     2821 ttctgggacc ctgatggatt acaaggatga cgaaggaact tctgaagaga agaagataaa
     2881 agtgatcctc aaagtcttag accccagcca cagggatatt tccctggcct tcttcgaggc
     2941 agccagcatg atgagacagg tctcccacaa acacatcgtg tacctctatg gcgtctgtgt
     3001 ccgcgacgtg gagaatatca tggtggaaga gtttgtggaa gggggtcctc tggatctctt
     3061 catgcaccgg aaaagtgatg tccttaccac accatggaaa ttcaaagttg ccaaacagct
     3121 ggccagtgcc ctgagctact tggaggataa agacctggtc catggaaatg tgtgtactaa
     3181 aaacctcctc ctggcccgtg agggcatcga cagtgagtgt ggcccattca tcaagctcag
     3241 tgaccccggc atccccatta cggtgctgtc taggcaagaa tgcattgaac gaatcccatg
     3301 gattgctcct gagtgtgttg aggactccaa gaacctgagt gtggctgctg acaagtggag
     3361 ctttggaacc acgctctggg aaatctgcta caatggcgag atccccttga aagacaagac
     3421 gctgattgag aaagagagat tctatgaaag ccggtgcagg ccagtgacac catcatgtaa
     3481 ggagctggct gacctcatga cccgctgcat gaactatgac cccaatcaga ggcctttctt
     3541 ccgagccatc atgagagaca ttaataagct tgaagagcag aatccagata ttgtttcaga
     3601 aaaaaaacca gcaactgaag tggaccccac acattttgaa aagcgcttcc taaagaggat
     3661 ccgtgacttg ggagagggcc actttgggaa ggttgagctc tgcaggtatg accccgaagg
     3721 ggacaataca ggggagcagg tggctgttaa atctctgaag cctgagagtg gaggtaacca
     3781 catagctgat ctgaaaaagg aaatcgagat cttaaggaac ctctatcatg agaacattgt
     3841 gaagtacaaa ggaatctgca cagaagacgg aggaaatggt attaagctca tcatggaatt
     3901 tctgccttcg ggaagcctta aggaatatct tccaaagaat aagaacaaaa taaacctcaa
     3961 acagcagcta aaatatgccg ttcagatttg taaggggatg gactatttgg gttctcggca
     4021 atacgttcac cgggacttgg cagcaagaaa tgtccttgtt gagagtgaac accaagtgaa
     4081 aattggagac ttcggtttaa ccaaagcaat tgaaaccgat aaggagtatt acaccgtcaa
     4141 ggatgaccgg gacagccctg tgttttggta tgctccagaa tgtttaatgc aatctaaatt
     4201 ttatattgcc tctgacgtct ggtcttttgg agtcactctg catgagctgc tgacttactg
     4261 tgattcagat tctagtgcca tggctttgtt cctgaaaatg ataggcccaa cccatggcca
     4321 gatgacagtc acaagacttg tgaatacgtt aaaagaagga aaacgcctgc cgtgcccacc
     4381 taactgtcca gatgaggttt atcaacttat gaggaaatgc tgggaattcc aaccatccaa
     4441 tcggacaagc tttcagaacc ttattgaagg atttgaagca cttttaaaac cccgggaggg
     4501 cccaccaggc ccatacaccg acatcgagat gaaccggctg ggcaagtaaa gatctaaggt
     4561 accaatctag agggccctat tctatagtgt cacctaaatg ctagagctcg ctgatcagcc
     4621 tcgactgtgc cttctagttg ccagccatct gttgtttgcc cctcccccgt gccttccttg
     4681 accctggaag gtgccactcc cactgtcctt tcctaataaa atgaggaaat tgcatcgcat
     4741 tgtctgagta ggtgtcattc tattctgggg ggtggggtgg ggcaggacag caagggggag
     4801 gattgggaag acaatagcag gcatgctggg gatgcggtgg gctctatggc ttctgaggcg
     4861 gaaagaacca gctggggctc gaggggggat ccccacgcgc cctgtagcgg cgcattaagc
     4921 gcggcgggtg tggtggttac gcgcagcgtg accgctacac ttgccagcgc cctagcgccc
     4981 gctcctttcg ctttcttccc ttcctttctc gccacgttcg ccggctttcc ccgtcaagct
     5041 ctaaatcggg ggctcccttt agggttccga tttagtgctt tacggcacct cgaccccaaa
     5101 aaacttgatt agggtgatgg ttcacgtagt gggccatcgc cctgatagac ggtttttcgc
     5161 cctttgacgt tggagtccac gttctttaat agtggactct tgttccaaac tggaacaaca
     5221 ctcaacccta tctcggtcta ttcttttgat ttataaggga ttttgccgat ttcggcctat
     5281 tggttaaaaa atgagctgat ttaacaaaaa tttaacgcga attttaacaa aatattaacg
     5341 cttacaattt aaatatttgc ttatacaatc ttcctgtttt tggggctttt ctgattatca
     5401 accggggtgg gtaccgagct cgaattctgt ggaatgtgtg tcagttaggg tgtggaaagt
     5461 ccccaggctc cccagcaggc agaagtatgc aaagcatgca tctcaattag tcagcaacca
     5521 ggtgtggaaa gtccccaggc tccccagcag gcagaagtat gcaaagcatg catctcaatt
     5581 agtcagcaac catagtcccg cccctaactc cgcccatccc gcccctaact ccgcccagtt
     5641 ccgcccattc tccgccccat ggctgactaa ttttttttat ttatgcagag gccgaggccg
     5701 cctcggcctc tgagctattc cagaagtagt gaggaggctt ttttggaggc ctaggctttt
     5761 gcaaaaagct cccgggagct tggatatcca ttttcggatc tgatcaagag acaggatgag
     5821 gatcgtttcg catgattgaa caagatggat tgcacgcagg ttctccggcc gcttgggtgg
     5881 agaggctatt cggctatgac tgggcacaac agacaatcgg ctgctctgat gccgccgtgt
     5941 tccggctgtc agcgcagggg cgcccggttc tttttgtcaa gaccgacctg tccggtgccc
     6001 tgaatgaact gcaggacgag gcagcgcggc tatcgtggct ggccacgacg ggcgttcctt
     6061 gcgcagctgt gctcgacgtt gtcactgaag cgggaaggga ctggctgcta ttgggcgaag
     6121 tgccggggca ggatctcctg tcatctcacc ttgctcctgc cgagaaagta tccatcatgg
     6181 ctgatgcaat gcggcggctg catacgcttg atccggctac ctgcccattc gaccaccaag
     6241 cgaaacatcg catcgagcga gcacgtactc ggatggaagc cggtcttgtc gatcaggatg
     6301 atctggacga agagcatcag gggctcgcgc cagccgaact gttcgccagg ctcaaggcgc
     6361 gcatgcccga cggcgaggat ctcgtcgtga cccatggcga tgcctgcttg ccgaatatca
     6421 tggtggaaaa tggccgcttt tctggattca tcgactgtgg ccggctgggt gtggcggacc
     6481 gctatcagga catagcgttg gctacccgtg atattgctga agagcttggc ggcgaatggg
     6541 ctgaccgctt cctcgtgctt tacggtatcg ccgctcccga ttcgcagcgc atcgccttct
     6601 atcgccttct tgacgagttc ttctgagcgg gactctgggg ttcgaaatga ccgaccaagc
     6661 gacgcccaac ctgccatcac gagatttcga ttccaccgcc gccttctatg aaaggttggg
     6721 cttcggaatc gttttccggg acgccggctg gatgatcctc cagcgcgggg atctcatgct
     6781 ggagttcttc gcccacccca acttgtttat tgcagcttat aatggttaca aataaagcaa
     6841 tagcatcaca aatttcacaa ataaagcatt tttttcactg cattctagtt gtggtttgtc
     6901 caaactcatc aatgtatctt atcatgtctg gatccgtcga cctcgagagc ttggcgtaat
     6961 catggtcata gctgtttcct gtgtgaaatt gttatccgct cacaattcca cacaacatac
     7021 gagccggaag cataaagtgt aaagcctggg gtgcctaatg agtgagctaa ctcacattaa
     7081 ttgcgttgcg ctcactgccc gctttccagt cgggaaacct gtcgtgccag ctgcattaat
     7141 gaatcggcca acgcgcgggg agaggcggtt tgcgtattgg gcgctcttcc gcttcctcgc
     7201 tcactgactc gctgcgctcg gtcgttcggc tgcggcgagc ggtatcagct cactcaaagg
     7261 cggtaatacg gttatccaca gaatcagggg ataacgcagg aaagaacatg tgagcaaaag
     7321 gccagcaaaa ggccaggaac cgtaaaaagg ccgcgttgct ggcgtttttc cataggctcc
     7381 gcccccctga cgagcatcac aaaaatcgac gctcaagtca gaggtggcga aacccgacag
     7441 gactataaag ataccaggcg tttccccctg gaagctccct cgtgcgctct cctgttccga
     7501 ccctgccgct taccggatac ctgtccgcct ttctcccttc gggaagcgtg gcgctttctc
     7561 atagctcacg ctgtaggtat ctcagttcgg tgtaggtcgt tcgctccaag ctgggctgtg
     7621 tgcacgaacc ccccgttcag cccgaccgct gcgccttatc cggtaactat cgtcttgagt
     7681 ccaacccggt aagacacgac ttatcgccac tggcagcagc cactggtaac aggattagca
     7741 gagcgaggta tgtaggcggt gctacagagt tcttgaagtg gtggcctaac tacggctaca
     7801 ctagaagaac agtatttggt atctgcgctc tgctgaagcc agttaccttc ggaaaaagag
     7861 ttggtagctc ttgatccggc aaacaaacca ccgctggtag cggtggtttt tttgtttgca
     7921 agcagcagat tacgcgcaga aaaaaaggat ctcaagaaga tcctttgatc ttttctacgg
     7981 ggtctgacgc tcagtggaac gaaaactcac gttaagggat tttggtcatg agattatcaa
     8041 aaaggatctt cacctagatc cttttaaatt aaaaatgaag ttttaaatca atctaaagta
     8101 tatatgagta aacttggtct gacagttacc aatgcttaat cagtgaggca cctatctcag
     8161 cgatctgtct atttcgttca tccatagttg cctgactccc cgtcgtgtag ataactacga
     8221 tacgggaggg cttaccatct ggccccagtg ctgcaatgat accgcgagac ccacgctcac
     8281 cggctccaga tttatcagca ataaaccagc cagccggaag ggccgagcgc agaagtggtc
     8341 ctgcaacttt atccgcctcc atccagtcta ttaattgttg ccgggaagct agagtaagta
     8401 gttcgccagt taatagtttg cgcaacgttg ttgccattgc tacaggcatc gtggtgtcac
     8461 gctcgtcgtt tggtatggct tcattcagct ccggttccca acgatcaagg cgagttacat
     8521 gatcccccat gttgtgcaaa aaagcggtta gctccttcgg tcctccgatc gttgtcagaa
     8581 gtaagttggc cgcagtgtta tcactcatgg ttatggcagc actgcataat tctcttactg
     8641 tcatgccatc cgtaagatgc ttttctgtga ctggtgagta ctcaaccaag tcattctgag
     8701 aatagtgtat gcggcgaccg agttgctctt gcccggcgtc aatacgggat aataccgcgc
     8761 cacatagcag aactttaaaa gtgctcatca ttggaaaacg ttcttcgggg cgaaaactct
     8821 caaggatctt accgctgttg agatccagtt cgatgtaacc cactcgtgca cccaactgat
     8881 cttcagcatc ttttactttc accagcgttt ctgggtgagc aaaaacagga aggcaaaatg
     8941 ccgcaaaaaa gggaataagg gcgacacgga aatgttgaat actcatactc ttcctttttc
     9001 aatattattg aagcatttat cagggttatt gtctcatgag cggatacata tttgaatgta
     9061 tttagaaaaa taaacaaata ggggttccgc gcacatttcc ccgaaaagtg ccacctgacg
     9121 tcgacggatc gggagatctc ccgatcccct atggtgcact ctcagtacaa tctgctctga
     9181 tgccgcatag ttaagccagt atctgctccc tgcttgtgtg ttggaggtcg ctgagtagtg
     9241 cgcgagcaaa atttaagcta caacaaggca aggcttgacc gacaattgca tgaagaatct
     9301 gcttagggtt aggcgttttg cgctgcttcg cgatgtacgg gccagatata cgcgtt
//
