LOCUS       sequence-29294-e         709 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 709)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 709)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAP3K5
FEATURES             Location/Qualifiers
     source          1..709
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    11..110
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 tcagctggag gcaataatga ttttattttg actgatagtg acctgttcgt tgcaacaaat
       61 tgataagcaa tgctttctta taatgccaac tttgtacaag aaagttggca aagtctgttt
      121 gtttcgaaag tcaatgatag ccttccacag tgtgcacagc atccctcccc ttagtctcaa
      181 gcattttaag tcatcacgtg taacatagta gagaacatcc aatagtgtat aatcttcagc
      241 caaaaaccgg cttatagtgt cttcatcagc tccattcact ctcagccagt cggtaagttc
      301 agaatcttca gtatttgtgc cagaagaatt tagatgaaat acaggcaatt caggaatttc
      361 tatgggttgg gacttaagct tcaggtgttt aatttcttgg tctttttctt caatagctcg
      421 atgaaggagt gcttgtaatt ctttctcttt ccgaaccaat tcttccagta atctattggt
      481 ttctattttc atccttccaa gctgtacatt cagtgaccgg tgagcactct gggaatcatg
      541 agacacagta gaactgagcg tgctcacgcc tgaggtagcc acagcatctt caatgacagc
      601 ctgaggtctt cggacagttt gatttgaagg ctgttcctca tggtcatctt ctacatccaa
      661 gtcttcttga tcagcagtat cactctcaga tgcaaggctg aaatgtggc
//
