LOCUS       sequence-29314-e         610 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 610)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKACA
FEATURES             Location/Qualifiers
     source          1..610
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    9..108
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gctcgggccc aataatgatt ttattttgac tgatagtgac ctgttcgttg caacaaattg
       61 atgagcaatg cttttttata atgccaactt tgtacaaaaa agttggcacc atgggcaacg
      121 ccgccgccgc caagaagggc agcgagcagg agagcgtgaa agaattctta gccaaagcca
      181 aagaagattt tcttaaaaaa tgggaaagtc ccgctcagaa cacagcccac ttggatcagt
      241 ttgaacgaat caagaccctc ggcacgggct ccttcgggcg ggtgatgctg gtgaaacaca
      301 aggagaccgg gaaccactat gccatgaaga tcctcgacaa acagaaggtg gtgaaactga
      361 aacagatcga acacaccctg aatgaaaagc gcatcctgca agctgtcaac tttccgttcc
      421 tcgtcaaact cgagttctcc ttcaaggaca actcaaactt atacatggtc atggagtacg
      481 tgcccggcgg ggagatgttc tcacacctac ggcggatcgg aaggttcagt gagccccatg
      541 cccgtttcta cgcggcccag atcgtcctga cctttgagta tctgcactcg ctggatctca
      601 tctacaggga
//
