LOCUS       sequence-29417-e         613 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 613)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 613)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-SH3BP5
FEATURES             Location/Qualifiers
     source          1..613
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    75..99
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
     regulatory      573..582
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 caataatgat tttattttga ctgatagtga cctgttcgtt gcaacaaatt gatgagcaat
       61 gcttttttat aatgccaact ttgtacaaaa aagttggcat ggagcagggg ctggaggagg
      121 aagaagaggt ggatccccgg atccagggag aactggagaa gttaaatcag tccacggatg
      181 atatcaacag acgggagact gaacttgagg atgctcgtca gaagttccgc tctgttctgg
      241 ttgaagcaac ggtgaaactg gatgaactgg tgaagaaaat tggcaaagct gtggaagact
      301 ccaagcccta ctgggaggca cggagggtgg cgaggcaggc tcagctggaa gctcagaaag
      361 ccacgcagga cttccagagg gccacagagg tgctccgtgc cgccaaggag accatctccc
      421 tggccgagca gcggctgctg gaggatgaca agcggcagtt cgactccgcc tggcaggaga
      481 tgctgaatca cgccactcag agggtcatgg aggcggagca gaccaagacc aggagcgagc
      541 tggtgcataa ggagacggca gccaggtaca atgccgccat gggccgcatg cgacagctgg
      601 agaagaaact caa
//
